Preparation method for plaster for promoting blood circulation to remove meridian obstruction

A technique of promoting blood circulation, dredging collaterals, and pasting plasters, which is applied to medical preparations containing no active ingredients, medical preparations containing active ingredients, and medical formulas. It can solve problems such as low prices, restrictions on wide application, and adverse reactions. Accurate dosage, good transdermal absorption and good compatibility

Inactive Publication Date: 2017-03-29
周益铭
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

While western medicine treats pain efficiently, oral anti-inflammatory and analgesic drugs are often used, but because of the strong gastrointestinal reactions, it brings many adverse reactions and brings new pain to patients, and the social and economic costs of treatment are relatively high , which limits its wide application to some extent
The treatment of muscle and joint pain with traditional Chinese medicine has the characteristics of flexible methods, significant curative effect, relatively small adverse reactions, and relatively low price. The use of traditional Chinese medicine, acupuncture and other treatments has certain curative effects and advantages, but some patients still cannot accept the taste of traditional Chinese medicine and acupuncture

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0016] Weigh 8g Guiwei, 8g Chishao, 8g peach kernel, 10g safflower, 8g Cyperus cyperi, 9g Qingpi, 9g Wang Buliuxing, 8g madder, 9g Zeilan, 10g Achyranthes bidentata, add 600mL deionized water, heat and cook for 1h After filtration, the filtrate was collected, and the filter residue was added to 600mL deionized water to continue cooking for 1h, then filtered, the filtrate was combined, and evaporated to dryness in a rotary evaporator to obtain the blood circulation agent; weigh 6.0g sodium polyacrylate NP-700 , 0.24g of aluminum dihydroxyaminoacetate, 5g of nano-aluminum hydroxide, 0.10g of disodium ethylenediaminetetraacetate, added to 30mL of glycerin, stirred at 300r / min for 15min, then added 5g of the above blood-activating and dredging agent, and continued to stir for 20min, Obtain the oil phase; weigh 0.10 g of carbomer, add 50 mL of 40% propylene glycol solution in mass fraction, stir at 300 r / min for 10 h, then add 2.0 g of povidone and 0.20 g of tartaric acid, and conti...

example 2

[0019] Weigh 9g Guiwei, 9g Radix Paeoniae Rubra, 9g peach kernel, 11g safflower, 9g Cyperus cyperi, 9g Qingpi, 9g Wangbuliuxing, 9g madder, 9g Eupatorium, 10g Achyranthes bidentata, add 700mL deionized water, heat and cook for 1.5 After h, filter, collect the filtrate, and add the filter residue to 700mL deionized water to continue cooking for 1.5h, then filter, combine the filtrate, and evaporate to dryness in a rotary evaporator to obtain blood circulation agent; weigh 6.5g sodium polyacrylate NP -700, 0.25g aluminum dihydroxyaminoacetate, 5.5g nano-aluminum hydroxide, 0.11g disodium ethylenediaminetetraacetate, add to 35mL glycerin, stir at 350r / min for 18min, then add 5.5g of the above-mentioned promoting blood circulation agent, Continue to stir for 25 minutes to obtain the oil phase; weigh 0.11g of carbomer, add 55mL of 40% propylene glycol solution in mass fraction, stir at 360r / min for 11h, then add 2.2g of povidone, 0.22g of tartaric acid, and continue to stir for 35mi...

example 3

[0022] Weigh 10g Guiwei, 10g Radix Paeoniae Rubra, 10g peach kernel, 12g safflower, 10g Cyperus cyperi, 10g Qingpi, 10g Wangbuliuxing, 10g madder, 10g Eupatorium, 12g Achyranthes bidentata, add 800mL deionized water, heat and cook for 2 hours After filtration, the filtrate was collected, and the filter residue was added to 800mL deionized water to continue cooking for 2h, then filtered, the filtrate was combined, and evaporated to dryness in a rotary evaporator to obtain a blood-activating agent; weigh 7.2g of sodium polyacrylate NP-700 , 0.28g of aluminum dihydroxyaminoacetate, 6g of nano-aluminum hydroxide, 0.12g of disodium edetate, added to 40mL of glycerin, stirred at 400r / min for 20min, then added 6g of the above blood-activating and dredging agent, and continued to stir for 30min, Obtain the oil phase; weigh 0.12g of carbomer, add 60mL of 40% propylene glycol solution in mass fraction, stir at 400r / min for 12h, then add 2.4g of povidone, 0.24g of tartaric acid, and conti...

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PUM

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Abstract

The invention relates to a preparation method for a plaster for promoting blood circulation to remove meridian obstruction, and belongs to the technical field of externally used plasters. The preparation method comprises the following steps that prescriptions of traditional Chinese medicine are adopted; decoction is conducted through water to extract effective components, and an agent for promoting blood circulation to remove meridian obstruction is prepared; the agent for promoting blood circulation to remove meridian obstruction, sodium polyacrylate, dihydroxy aluminum aminoacetate, nano aluminum hydroxide and the like are added to glycerine and mixed evenly, and an oil phase is obtained; a water phase is prepared from carbomer, tartaric acid, polyvinylpyrrolidone and the like; the water phase is added in the oil phase, a cross-linked network structure is formed, and cohesive strength is improved; and finally the cross-linked network structure is smeared on a non-woven fabric, silicone oil paper is laid to serve as an anti-sticking film, still standing is conducted until solidifying and molding are achieved, and the plaster for promoting blood circulation to remove meridian obstruction is obtained. According to the plaster for promoting blood circulation to remove meridian obstruction, the drug loading capacity is high; the administration dose is accurate and controllable; drug transdermal absorption is good; the biocompatibility of the plaster and the skin is good; and ventilation, sweat resistance, moisturizing, no clothes polluting, no fine hair pulling, repeated sticking, no allergy and no irritation are achieved.

Description

technical field [0001] The invention relates to a preparation method of a plaster for promoting blood circulation and dredging collaterals, and belongs to the technical field of plasters for external use. Background technique [0002] Muscle soreness and joint pain are one of the diseases that people often face in modern urban life. In recent years, the incidence of neck, shoulder, waist and leg pain has increased year by year, and the treatment of muscle and joint pain has become a public health problem. . While western medicine treats pain efficiently, oral anti-inflammatory and analgesic drugs are often used, but because of the strong gastrointestinal reactions, it brings many adverse reactions and brings new pain to patients, and the social and economic costs of treatment are relatively high , which limits its wide application to some extent. The treatment of muscle and joint pain with traditional Chinese medicine has the characteristics of flexible methods, significan...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8905A61K9/70A61K47/32A61P21/00A61P29/00A61P19/02
CPCA61K36/232A61K9/7023A61K36/21A61K36/286A61K36/36A61K36/53A61K36/65A61K36/71A61K36/736A61K36/74A61K36/752A61K36/8905A61K47/32A61K2236/331A61K2236/39A61K2300/00
Inventor 周益铭张潇
Owner 周益铭
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