The invention discloses an organic waste and animal excrement harmless treatment method. The method includes the first-stage fermentation step and the second-stage fermentation step. In the first-stage fermentation step, materials needing to be treated are continuously overturned and stirred, hot air is injected in the materials, ventilation is kept, and the materials are fermented for 3-7 days at high temperature under the action of high-oxygen-consumption microorganisms, so that the materials are deodorized and cured, and the water content is reduced to 35-45%. In the second-stage fermentation step, the materials are kept in the accumulated state for 5-8 days, and ventilation is continuous, so that the materials are fully cured, the water content is reduced to 20-30%, and the dried cured materials are formed. The aerobic fermentation mechanism of the microorganisms is used, the treated materials are overturned and subjected to oxygen adding, and ultrahigh temperature aerobic microorganism development is used, so that the temperature of the materials is over 70 DEG C, the materials can be quickly evaporated, dehydrated and cured, energy in organic matter is released, and various kinds of organic matter are oxidized. By means of the method, breeding waste, organic waste of agricultural product processing enterprises, waste of slaughter houses, organic waste generated in production, urban life waste, and farmer courtyard and farmland waste can be treated.