IP10 and interleukin combined cytokine for diagnosis of tuberculosis and kit thereof
A cytokine and IP-10 technology, applied in the field of disease diagnosis, can solve problems such as low accuracy of tuberculosis, sensitivity and specificity that cannot meet clinical requirements, and insufficient detection performance of IFN-γ, so as to improve diagnostic ability and high Effects of Sensitivity and Specificity
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Embodiment 1
[0042] In this study, the plasma levels of five cytokines including IFN-γ, IL-6, IP-10, Eotaxin and RANTES were detected in the plasma of newly diagnosed tuberculosis patients and healthy persons.
[0043] IFN-γ, IL-6, Eotaxin, IP-10 and RANTES five cytokines in plasma levels (mean ± standard deviation) of 213 cases of newly diagnosed pulmonary tuberculosis patients and plasma of 29 healthy persons (see Table 1). Make a scatterplot of the two groups based on the data. The levels of IL-6, Eotaxin, IP-10 and RANTES in the plasma of tuberculosis patients were significantly higher than those of healthy people (Pfigure 1 B. figure 1 C. figure 1 D and figure 1 E), the difference of IFN-γ between the two groups was not statistically significant ( figure 1 A).
[0044] Table 1 The levels of cytokines in the plasma of patients with newly diagnosed pulmonary tuberculosis and healthy subjects (mean ± standard deviation)
[0045]
[0046] ROC curve of plasma cytokines in patients ...
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Description
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Application Information
- IPC
- G01N33/68
- CPC
- G01N33/6893; G01N2333/522; G01N2333/5412; G01N2333/7155; G01N2333/7158; G01N2800/12
- Inventors
- 冯晓燕; 张贺秋