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A kind of traditional Chinese medicine compound preparation for treating diabetes and its preparation method and application

A compound preparation, diabetes technology, applied in pharmaceutical formulas, urinary system diseases, medical preparations containing active ingredients, etc. Sensitivity index, composition ratio of traditional Chinese medicine is scientific and reasonable, and the effect of high content of active ingredients

Active Publication Date: 2021-04-09
LANZHOU UNIVERSITY OF TECHNOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Astragalus, mulberry leaf, mulberry and lotus leaf, the prescription Qisang Jiangtang Fang, which is a combination of four traditional Chinese medicines, has shown a good hypoglycemic effect as a folk prescription, but it lacks scientific support, and the specific hypoglycemic mechanism has not been found. any reports

Method used

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  • A kind of traditional Chinese medicine compound preparation for treating diabetes and its preparation method and application
  • A kind of traditional Chinese medicine compound preparation for treating diabetes and its preparation method and application
  • A kind of traditional Chinese medicine compound preparation for treating diabetes and its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] 1. Formula (in parts by weight):

[0028] 12 parts of astragalus, 12 parts of mulberry, 10 parts of mulberry leaves, 10 parts of lotus leaves

[0029] 2, preparation method, comprises the following steps:

[0030] (1) Take 12 parts of astragalus, 12 parts of mulberry, 10 parts of mulberry leaves, and 10 parts of lotus leaves, decoct twice with 10 times the amount of water, decoct for 40 minutes for the first time, and 30 minutes for the second time, and combine The decocting solution is filtered and concentrated to obtain a concentrated solution for subsequent use;

[0031] (2) Get 12 parts of astragalus, 12 parts of mulberry fruit, 10 parts of mulberry leaves, and 10 parts of lotus leaves, and use 8 times the concentration of 60% ethanol to reflux extract twice, each time for 1 hour, combine the extracts, and decompress Concentrate to obtain a concentrated solution for subsequent use;

[0032] (3) Mix the concentrated solution obtained in step (1) and step (2) evenl...

Embodiment 2

[0034] 1. Formula (in parts by weight):

[0035] 12 parts of astragalus, 12 parts of mulberry, 10 parts of mulberry leaves, 10 parts of lotus leaves

[0036] 2, preparation method, comprises the following steps:

[0037] (1) Take 12 parts of astragalus, 12 parts of mulberry, 10 parts of mulberry leaves, and 10 parts of lotus leaves, decoct twice with 10 times the amount of water, decoct for 40 minutes for the first time, and 30 minutes for the second time, and combine The decocting solution is filtered and concentrated to obtain a concentrated solution for subsequent use;

[0038] (2) Get 12 parts of astragalus, 12 parts of mulberry fruit, 10 parts of mulberry leaves, and 10 parts of lotus leaves, and use 8 times the concentration of 60% ethanol to reflux extract twice, each time for 1 hour, combine the extracts, and decompress Concentrate to obtain a concentrated solution for subsequent use;

[0039] (3) Add appropriate amount of starch and xylitol to the concentrated solu...

Embodiment 3

[0041] 1. Formula (in parts by weight):

[0042] 12 parts of astragalus, 12 parts of mulberry, 10 parts of mulberry leaves, 10 parts of lotus leaves

[0043] 2, preparation method, comprises the following steps:

[0044] (1) Take 12 parts of astragalus, 12 parts of mulberry, 10 parts of mulberry leaves, and 10 parts of lotus leaves, decoct twice with 10 times the amount of water, decoct for 40 minutes for the first time, and 30 minutes for the second time, and combine The decocting solution is filtered and concentrated to obtain a concentrated solution for subsequent use;

[0045] (2) Get 12 parts of astragalus, 12 parts of mulberry fruit, 10 parts of mulberry leaves, and 10 parts of lotus leaves, and use 8 times the concentration of 60% ethanol to reflux extract twice, each time for 1 hour, combine the extracts, and decompress Concentrate to obtain a concentrated solution for subsequent use;

[0046] (3) Add appropriate amount of starch and xylitol to the concentrated solu...

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Abstract

The invention relates to a traditional Chinese medicine compound preparation for treating diabetes and its preparation method and application. It is prepared from the following raw materials in parts by weight: 6-18 parts of astragalus, 6-18 parts of mulberry, 5-15 parts of mulberry leaves, lotus root leaves 5-15 parts; the preparation method of the Chinese medicine compound preparation is decocting, filtering, and concentrating to obtain a concentrated solution for subsequent use; after extraction and concentration under reduced pressure, a concentrated solution is obtained for subsequent use; the decocted concentrated solution and the extracted The concentrated solution obtained and the pharmaceutically acceptable carrier are prepared into oral liquid, granules, capsules, and tablet dosage forms; the Chinese medicine compound provided by the present invention achieves Reduce blood sugar, blood lipid, BUN and SCr content, and reduce the expression of NF‑κB and ICAM‑1 in renal tissue, improve insulin sensitivity index, and finally achieve the purpose of improving diabetic renal function.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a compound traditional Chinese medicine preparation for treating diabetes and its preparation method and application. Background technique [0002] In recent years, with changes in various factors such as the economy, environment, and lifestyle, the prevalence of diabetes has shown an accelerated upward trend. Currently, more than 100 million people in China suffer from diabetes. The disease can occur at any age, and As the course of the disease prolongs, it will lead to complications of blood vessels, heart, kidneys and other organs. If active treatment measures are not taken in the early stage of diabetes, diabetic patients will not receive good treatment and management, and the number of diabetic patients in my country will increase significantly. This will bring heavy mental pressure and economic burden to the healthy development of our society...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/62A61P3/10A61P13/12
CPCA61K36/481A61K36/605A61K36/62A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 蒲秀瑛李海兵李浩文马建忠张伟杰李晓玥任菁刘璐马小龙续文君
Owner LANZHOU UNIVERSITY OF TECHNOLOGY
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