Application of 4-hydroxyl-2-pyridone alkaloid in preparing antitumor product

Abstract

The invention discloses application of 4-hydroxyl-2-pyridone alkaloid in preparing an antitumor product. The 4-hydroxyl-2-pyridone alkaloid is Sambutoxin, and a chemical structure of the 4-hydroxyl-2-pyridone alkaloid is shown in the description. Through researches of animal experiments, cell experiments and the like, the compound is shown to have very strong antitumor activity on varieties of tumor cells including lung cancer, cervical cancer, colon cancer and breast cancer; the compound has the advantages of obvious effects, safety, low toxin, convenience in use and rich and cheap raw material sources; a preparation technology has the advantages of simpleness, high yield, stable characters, convenience in quality control, lower production cost and convenience in application production; anovel medicine source and a safe raw material are provided for treating and researching antitumor and direct related diseases of the antitumor.

Description

technical field

[0001] The invention relates to the technical field of medicine, in particular to the application of a 4-hydroxy-2-pyridone alkaloid in the preparation of antitumor products. Background technique

[0002] Tumor is a frequently-occurring and common disease that seriously endangers human health and life. As early as 2000-3000 years ago, there were records about tumors in Egypt and my country. In many countries including China, especially in moderately developed countries, the death caused by cancer occupies the first or second place among all the causes of death, and the incidence rate is still on the rise worldwide. Tumor is an abnormal lesion formed by the body under the action of various carcinogenic factors when a certain cell in a local tissue loses its normal regulation of its growth at the gene level, resulting in its clonal abnormal proliferation. Generally divided into benign and malignant two categories. All malignant tumors are collectively called ...

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