Traditional Chinese medicine formula for treating hypertension and product thereof

A high blood pressure and traditional Chinese medicine technology, applied in the field of medicine, can solve the problems that need to be improved, the effect is not durable, and the blood pressure is small, and the effect of reducing blood pressure, lasting blood pressure, and reducing systolic blood pressure and diastolic blood pressure can be achieved.

Active Publication Date: 2018-02-02
谭元生 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The patent ZL201010125992.2 authorized by the inventor of the present application also discloses a traditional Chinese medicine composition for treating hypertension, which is made of the following traditional Chinese medicine raw materials in proportions by weight: 1-2 parts of Rhizoma Chuanxiong, 1.5-2 parts of Uncaria, Ophiopogon japonicus 1-1.5 parts, but the effect of this traditional Chinese medicine composition in nourishing yin, softening the liver and calming the wind, promoting blood circulation, dredging the meridian and stopping dizziness, and lasting drug eff

Method used

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  • Traditional Chinese medicine formula for treating hypertension and product thereof
  • Traditional Chinese medicine formula for treating hypertension and product thereof
  • Traditional Chinese medicine formula for treating hypertension and product thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] The granule dosage form of embodiment 1 pharmaceutical composition of the present invention

[0019] Using the conventional method of preparing granules, take 4 parts of Gastrodia elata, 3 parts of Uncaria, 6 parts of Rauwolfia, 4 parts of Chuanxiong, and 4 parts of Pinellia chinensis, soak in water for 0.5 hours and extract twice, adding water respectively 10 times, 8 times times, the first extraction for 2 hours, the second extraction for 1.5 hours, filtering, combining the filtrates, concentrating, drying, pulverizing, adding appropriate amount of excipients, mixing, granulating, sieving, and drying to obtain a pharmaceutical composition in the form of granules preparation.

Embodiment 2

[0020] Tablet dosage form of embodiment 2 pharmaceutical composition of the present invention

[0021] Using the conventional method for preparing tablets, take 0.5 parts of Gastrodia elata, 0.8 parts of Uncaria, 0.8 parts of Rauwolfia, 1 part of Rhizoma Chuanxiong, and 0.5 parts of Pinellia chinensis, add 70% ethanol to soak for 0.5 hours, and then extract twice. The amount of water added is respectively 6 times, 4 times, extract for 2 hours for the first time, extract for 1 hour for the second time, filter, combine the filtrate, concentrate, dry, crush, add appropriate amount of auxiliary materials, mix, granulate, sieve, dry, and the obtained The granules are further compressed into tablets and dried to obtain a pharmaceutical composition preparation in the form of tablets.

Embodiment 3

[0022] The capsule dosage form of embodiment 3 pharmaceutical compositions of the present invention

[0023] Using the conventional method for preparing capsules, take 1 part of Gastrodia elata, 2 parts of Uncaria, 2 parts of Rauwolfia, 1 part of Chuanxiong, 0.8 parts of Pinellia chinensis, 1 part of wild chrysanthemum, 1 part of Poria cocos, 1 part of tangerine peel, add 60% After soaking in ethanol for 0.5 hours, extract twice, add water 7 times and 5 times respectively, extract for 2 hours for the first time, extract for 1 hour for the second time, filter, combine the filtrates, concentrate, dry, crush, add appropriate amount of excipients, and mix well , granulating, sieving, drying, and filling the prepared granules into capsule shells to make capsules, that is, to make a pharmaceutical composition preparation in the form of capsules.

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PUM

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Abstract

The invention discloses compound traditional Chinese medicine for treating hypertension. The compound traditional Chinese medicine is prepared from the raw materials of rhizoma gastrodiae, uncariae ramulus cum uncis, rhizoma chuanxiong, rauwolfia root, rhizoma pinelliae praeparatum and the like, and the raw materials are extracted and separated by a 0 to 75% ethanol water solution to be prepared into certain dosage forms. The compound traditional Chinese medicine has the effects of suppressing hyperactive liver for calming endogenous wind and eliminating phlegm by cooling and can be applied toprimary hypertension or refractory hypertension liver fire hyperactivity and phlegm heat accumulation patients. Pharmacodynamic study shows that the compound traditional Chinese medicine can obviously reduce systolic pressure and diastolic pressure of spontaneous hypertension and renal hypertension model animals and has a durable blood pressure lowering effect. Clinical research results show thatthe medicine disclosed by the invention can effectively improve all traditional Chinese medicine symptoms of the hypertension liver fire hyperactivity and phlegm heat accumulation patients, can effectively reduce blood pressure of the patient and has no obvious adverse drug reaction. The compound traditional Chinese medicine can be applied to treating hypertension, is safe and effective and has convenience in use; clinical effects and pharmacodynamic study prove that the compound traditional Chinese medicine disclosed by the invention has the functions of suppressing hyperactive liver for calming endogenous wind and eliminating phlegm by cooling and is effective dedicated medicine for treating hypertension.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a compound traditional Chinese medicine for treating hypertension. Background technique [0002] Hypertension is a clinical syndrome characterized by elevated systemic arterial systolic blood pressure (SBP) and / or diastolic blood pressure (DBP). Its high disability rate and death rate have brought serious material and spiritual damage to society and families. In my country, the prevalence rate of people over 15 years old is 11.2%, and the prevalence rate of people over 60 years old is as high as 43.7%. It is estimated that among the 1.3 billion people in my country, the total number of hypertensive patients is about 120 million, and hypertensive patients have lifelong characteristics of medication. [0003] At present, the six major types of drugs used in the treatment of hypertension by western medicine are still the main antihypertensive drugs in clinical applicat...

Claims

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Application Information

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IPC IPC(8): A61K36/8988A61P9/12
CPCA61K36/076A61K36/236A61K36/24A61K36/287A61K36/74A61K36/752A61K36/8888A61K36/8988A61K2236/331A61K2236/333A61K2300/00
Inventor 王宇红谭元生
Owner 谭元生
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