Traditional Chinese medicine composition for treating hypertension and preparation method of traditional Chinese medicine composition

Abstract

The invention discloses a traditional Chinese medicine composition for treating hypertension and a preparation method thereof. The traditional Chinese medicine composition is composed of the following raw materials in parts by weight: 10-20 parts of peach kernel, 9-20 parts of safflower, 5-15 parts of red peony root, Danpi 8‑23 parts, Motherwort 9‑23 parts, Achyranthes bidentata 5‑13 parts, Salvia miltiorrhiza 10‑30 parts, Curcuma 5‑16 parts, Puhuang 10‑25 parts, Panax notoginseng 10‑25 parts, Scutellaria baicalensis 6‑17 parts Coptidis 9‑20 parts, Anemarrhena 10‑20 parts, Prunella vulgaris 10‑24 parts, chrysanthemum 6‑13 parts, Sophora japonica 5‑19 parts. The traditional Chinese medicine composition for treating hypertension provided by the invention has remarkable effect on treating hypertension, has little side effects on human body, and has a simple preparation method.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating hypertension and a preparation method thereof. Background technique [0002] At present, there are more than 100 million hypertensive patients in my country, most of which have unknown causes and are a lifelong disease. Long-term and effective implementation of antihypertensive drug therapy is one of the main ways to improve the quality of life and survival rate of hypertensive patients. It has become a consensus in the academic community that hypertensive patients need to use antihypertensive drugs for life. The good control of blood pressure mainly depends on the effect of drugs, adverse drug reactions, patient compliance and treatment costs. At present, several types of drugs commonly used in clinical treatment of hypertension are mainly diuretics, heatstroke α-receptor stimulants and pe...

AI Technical Summary

Problems solved by technology

This single drug can generally only control the blood pressure of 40%-60% or less patients, and the dose-effect curve of commonly used drugs is low and flat, and the effect is not good. When the dose is increased, the curative effect does not increase much, and the side effects can increase logarithmically. After antihypertensive drugs, the body's compensatory mechanism can produce counter-regulation, which can reduce or offset the antihypertensive effect

[0003] In view of the shortcomings of single preparations in the treatment of hypertension, although clinicians can prescribe a combination of two or more different medicines according to the treatment needs of patients, the following treatment defects still exist: (1) the above-mentioned medicines for the treatment of hypertension A considerable part of the drugs have a large hepatic first-pass effect, and oral administration requires a large dose to reach the effective blood concentration, which increases the cost of treatment, but the treatment efficiency is low; (2) drug absorption is greatly affected by gastrointestinal factors, and drug absorption There are large individual differences in metabolism and metabolism in the body, and the curative effect is uncertain and uncontrollable; (3) frequent administration is required, and the treatment of hypertension is a long-term behavior, which usually requires life-long medication, and the patient's treatment remains unchanged and the compliance is low; (4) based on unilateral Due to the low and flat dose-effect curve of the drug, the effective therapeutic effect is usually achieved by increasing the dose of the drug, but this usually causes relatively large toxic and side effects and increases the incidence of adverse reactions

(5) It is inconvenient to use combined medication