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Preparation method of traditional Chinese medicine composition for treating depression

A composition and technology for depression, applied in the medical field, can solve the problems of low recognition rate of depression, high requirements for equipment and environment, etc., and achieve the effect of fast onset, low cost and definite curative effect

Inactive Publication Date: 2018-05-04
CHENGDU JINHUI TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Depression is the fourth largest disease in the world, and it is expected to become the second largest by 2020; however, the medical prevention and treatment of depression in my country is still in a situation of low recognition rate, and the recognition rate of hospitals above prefecture-level cities is less than 20%. Less than 10% of patients received relevant drug treatment; and, at the same time, the onset of depression (and suicide) has begun to appear younger (university, and even primary and secondary school students) trend
However, the current preparation method of drugs for treating depression has too high requirements for equipment and environment, and general pharmaceutical factories need to invest huge sums of money to improve and upgrade existing plant equipment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] A preparation method of a traditional Chinese medicine composition for treating depression, which is characterized in that: weighing Bupleurum, Magnolia officinalis, Citrus aurantii, Coptidis Rhizoma, Chuanxiong and Pinellia, adding 10-12 times the amount of 35%-60% ethanol to extract 2 -3 times, 1-2 hours each time, after filtering, combine the filtrates, recover ethanol under reduced pressure, and dry under reduced pressure below 40°C; then add gardenia, licorice and epimedium, stir together to form powder, and mix well to obtain active ingredient of the composition. The manufacturing method of the present invention is simple, and the process is not complicated, and the requirements for the process environment are not high, and domestic enterprises can easily manufacture it without additional investment and purchase of production equipment. The invention fully adopts the components of traditional Chinese medicines, has the functions of antidepressant and anti-anxiety,...

Embodiment 2

[0016] A method for preparing a traditional Chinese medicine composition for treating depression, comprising weighing Bupleuri, Magnolia officinalis, Citrus aurantii, Coptidis Rhizoma, Chuanxiong and Pinellia, adding 10-12 times the amount of 35%-60% ethanol to extract 2-3 times, Each time for 1-2 hours, filter and combine the filtrates, recover ethanol under reduced pressure, and dry under reduced pressure below 40°C; then add gardenia, licorice and epimedium, stir together into powder, and mix well to obtain the active ingredient of the composition. Element. 30-50 parts of Bupleurum bupleuri, 20-30 parts of Magnolia officinalis, 20-30 parts of Citrus aurantii, 5-25 parts of Coptidis rhizome, 12-20 parts of Chuanxiong, and 18-33 parts of pinellia. 15-20 parts of gardenia, 15-20 parts of licorice, 10-15 parts of epimedium. The manufacturing method of the present invention is simple, and the process is not complicated, and the requirements for the process environment are not h...

Embodiment 3

[0018] A method for preparing a traditional Chinese medicine composition for treating depression, comprising weighing Bupleuri, Magnolia officinalis, Citrus aurantii, Coptidis Rhizoma, Chuanxiong and Pinellia, adding 10-12 times the amount of 35%-60% ethanol to extract 2-3 times, Each time for 1-2 hours, filter and combine the filtrates, recover ethanol under reduced pressure, and dry under reduced pressure below 40°C; then add gardenia, licorice and epimedium, stir together into powder, and mix well to obtain the active ingredient of the composition. Element. 40 parts of Bupleurum bupleuri, 26 parts of Magnolia officinalis, 27 parts of Citrus aurantii, 13 parts of Coptidis rhizome, 14 parts of Chuanxiong, and 23 parts of pinellia. 17 parts of gardenia, 16 parts of licorice, 11 parts of epimedium. The manufacturing method of the present invention is simple, and the process is not complicated, and the requirements for the process environment are not high, and domestic enterpri...

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Abstract

The invention relates to the field of medicine, and specifically relates to a preparation method of a traditional Chinese medicine composition for treating depression. The preparation method comprisesthe following steps: weighing radix bupleuri, magnolia cortex, bitter orange, coptis, ligusticum wallichii, and pinellia ternate, adding ethanol (35-60%) into raw materials, wherein the ratio of ethanol to raw materials is 10-12:1; carrying out extraction for 2 to 3 times, wherein each extraction lasts for 1 to 2 hours; filtering, merging the filtrates, carrying out reduced pressure distillationto recover ethanol, carrying out reduced pressure drying at a temperature lower than 40 DEG C; then adding cape jasmine, licorice root, and epimedium, stirring, pulverizing the mixture, and evenly mixing to obtain the active component of the composition. The manufacturing method is simple, the technology is not complicated, the requirements on technology and environment are not high, the domesticenterprises can easily produce the traditional Chinese medicine composition, and extra investment on production equipment is not needed.

Description

technical field [0001] The invention relates to the medical field, in particular to a preparation method of a traditional Chinese medicine composition for treating depression. Background technique [0002] Depression, also known as depressive disorder, is the main type of mood disorder with significant and persistent low mood as the main clinical feature. It can be seen clinically that the mood is not commensurate with the situation. The depression of mood can range from gloomy to distraught, low self-esteem and depression, even pessimistic world-weariness, and there may be suicide attempts or behaviors; even stupor; some cases have obvious anxiety and motor agitation; In severe cases, psychotic symptoms such as hallucinations and delusions may appear. Each attack lasts for at least 2 weeks, or even several years in the elderly. Most cases have a tendency to recur. Most of each attack can be relieved, and some may have residual symptoms or become chronic. Depression is the...

Claims

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Application Information

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IPC IPC(8): A61K36/8888A61P25/24
CPCA61K36/8888A61K36/233A61K36/236A61K36/296A61K36/484A61K36/575A61K36/718A61K36/744A61K36/752A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 张一帆
Owner CHENGDU JINHUI TECH
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