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Chlortetracycline premix

A technology of premix and chlortetracycline, which is applied in the direction of tetracycline active ingredients, digestive system, drug combination, etc., can solve problems such as difficult intestinal therapeutic effects and reduced drug efficacy, and achieve good application prospects and release of chlortetracycline The effect of less, high utilization rate

Inactive Publication Date: 2018-02-23
江苏昕宇药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Chlortetracycline is often used in the treatment of intestinal-related diseases due to its good effect, but the existing aureomycin premix is ​​quickly dissolved in the stomach by gastric juice after use, so that aureomycin is quickly dissolved before it reaches the intestinal tract. Absorbed, greatly reducing its original efficacy, it is difficult to play a good therapeutic effect on the intestinal tract, so further research is needed

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] A chlortetracycline premix comprises the following components in parts by weight: 20 parts of chlortetracycline hydrochloride, 17 parts of corn starch, 1.9 parts of N-trimethyl chitosan, 4 parts of sucrose and 7 parts of dextrin.

Embodiment 2

[0015] A chlortetracycline premix comprises the following components in parts by weight: 24 parts of chlortetracycline hydrochloride, 12 parts of corn starch, 2.3 parts of N-trimethyl chitosan, 4.9 parts of lactose and 8 parts of dextrin.

[0016] This kind of chlortetracycline premix, the quality of the chlortetracycline premix prepared by this prescription is stable, the utilization rate is high, the release of chlortetracycline in the gastric juice is less, it can well reach the intestinal tract and play a good role in medicine. It has a good application prospect and is worthy of popularization.

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PUM

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Abstract

The invention discloses a chlortetracycline premix, which consists of the following components in parts by weight: 15-25 parts of chlortetracycline hydrochloride, 10-20 parts of corn starch, 1-3 partsof N-trimethyl chitosan, 3-6 parts of a sweetening agent and 6-12 parts of a binding agent. The chlortetracycline premix, which is prepared in accordance with the prescription, is stable in quality and high in utilization rate; chlortetracycline, which is less released in gastric juice, can reach an intestinal tracts well so as to achieve good efficacy; and the chlortetracycline premix has a goodapplication prospect and is worthy of popularizing.

Description

technical field [0001] The invention relates to a chlortetracycline premix, which belongs to the technical field of pharmaceutical excipients. Background technique [0002] Chlortetracycline is often used in the treatment of intestinal-related diseases due to its good effect, but the existing aureomycin premix is ​​quickly dissolved in the stomach by gastric juice after use, so that aureomycin is quickly dissolved before it reaches the intestinal tract. Absorbed, greatly reducing its original efficacy, it is difficult to play a good therapeutic effect on the intestinal tract, so further research is needed. Contents of the invention [0003] In order to overcome the deficiencies in the prior art, the invention provides a kind of chlortetracycline premix, the quality of the chlortetracycline premix that is made by this prescription is stable, and utilization rate is high, and aureomycin releases relatively fast in gastric juice. less, can well reach the intestinal tract and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/65A61K47/36A61P1/00
CPCA61K31/65A61K47/36
Inventor 王俭
Owner 江苏昕宇药业有限公司
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