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Pharmaceutical composition for treatment of hepatic cirrhosis and preparation method thereof

A composition and drug technology, applied in the direction of drug combination, pharmaceutical formula, medical raw materials derived from mollusks, etc., can solve the problems of many kinds of raw materials of traditional Chinese medicine composition, uncertain clinical efficacy, increased treatment cost, etc., and achieve significant therapeutic effect. , The curative effect is exact, the effect of eliminating discomfort symptoms

Inactive Publication Date: 2018-04-20
HENAN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many types of raw materials for the traditional Chinese medicine composition for the treatment of liver cirrhosis in this invention, which increases the cost of treatment, and the clinical efficacy is uncertain at the same time, which needs a lot of practical verification

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] Example 1: A pharmaceutical composition for the treatment of liver cirrhosis, made of the following raw materials in parts by weight: 15 parts of peach kernels, 15 parts of gerbera, 13 parts of Adenophora, 11 parts of Nanling Dalbergia, 11 parts of Jiangzhenxiang 9 parts of torreya snails, 9 parts of plantain seed, 7 parts of mountain branch kernel, 7 parts of orange leaf, 7 parts of root of Pinellia chinensis, and 7 parts of agarwood.

[0036] The preparation method of the above-mentioned pharmaceutical composition for liver cirrhosis treatment comprises the following steps:

[0037]Step S1: Weigh the dried peach kernels, gerbera, Adenophora, Nanling Dalbergia, Jiangzhenxiang, Torreya snails, Plantaginaceae, Shanzhiren, orange leaves, Pinellia chinensis roots and Agarwood, crush them, and pass 20 Mesh sieve, and the under-sieve is mixed to obtain a mixture;

[0038] Step S2: Put the mixture into an open container, slowly add an ethanol solution with a volume fraction ...

Embodiment 2

[0043] Example 2: A pharmaceutical composition for the treatment of liver cirrhosis, made of the following raw materials in parts by weight: 12 parts of peach kernels, 12 parts of gerbera, 10 parts of Adenophora japonicus, 10 parts of Dalbergia chinensis, 10 parts of Jiangzhenxiang 8 parts of torreya snails, 8 parts of plantain seed, 5 parts of mountain branch kernel, 5 parts of orange leaf, 5 parts of root of Pinellia chinensis, and 5 parts of agarwood.

[0044] The preparation method of the above-mentioned pharmaceutical composition for liver cirrhosis treatment comprises the following steps:

[0045] Step S1: Weigh the dried peach kernels, gerbera, Adenophora, Nanling Dalbergia, Jiangzhenxiang, Torreya snails, Plantaginaceae, Shanzhiren, orange leaves, Pinellia chinensis roots and Agarwood, crush them, and pass 10 Mesh sieve, and the under-sieve is mixed to obtain a mixture;

[0046] Step S2: Put the mixture into an open container, slowly add an ethanol solution with a vol...

Embodiment 3

[0050] Example 3: A pharmaceutical composition for the treatment of liver cirrhosis, made of the following raw materials in parts by weight: 16 parts of peach kernels, 16 parts of gerbera, 15 parts of Adenophora, 12 parts of Dalbergia chinensis, 12 parts of Jiangzhenxiang 10 parts of torreya snails, 10 parts of plantain seed, 8 parts of shanzhiren, 8 parts of orange leaves, 8 parts of Pinellia chinensis root, and 8 parts of agarwood.

[0051] The preparation method of the above-mentioned pharmaceutical composition for liver cirrhosis treatment comprises the following steps:

[0052] Step S1: Weigh the dried peach kernels, gerbera, Adenophora, Nanling Dalbergia, Jiangzhenxiang, Torreya snails, Plantaginaceae, Shanzhiren, orange leaves, Pinellia root and Agarwood, crush them, and pass 30 Mesh sieve, and the under-sieve is mixed to obtain a mixture;

[0053] Step S2: Put the mixture into an open container, slowly add ethanol solution, mix evenly, and fully infiltrate until the e...

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PUM

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Abstract

The invention provides a pharmaceutical composition for treatment of hepatic cirrhosis and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 10-20 parts of peach kernel, 10-20 parts of herba gerberae piloselloidis, 9-17 parts of radix glehniae, 8-15 partsof dalbergia balansae, 8 to 15parts of dalbergia wood, 6 to 12 parts of olive shell, 6 to 12 parts of semen plantaginis, 3 to 10 parts of glabrousleaf pittosporum seed, 3 to 10 parts of tangerine leaf, 3 to 10 parts of elaeagnus multiflora root and 3 to 10 parts of agilawood. The pharmaceutical composition has the effects of relieving liver and regulating qi, clearing away heat and dampness, promoting blood circulation, removing stasis, reducing swelling and detoxifying, is suitable for the treatment of patients with the hepatic cirrhosis of liver qi stagnation and retention of damp-heat in the interior, and can significantly improve or eliminate many uncomfortable symptoms of the patients with the hepatic cirrhosis, including abdominal distension, oliguria, swelling after eating, pale tongue, thin tongue fur, slimy tongue fur, abdominal pain, yellowish skin and eyes, loose stools, and fatigue and the like.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and in particular relates to a pharmaceutical composition for treating liver cirrhosis and a preparation method thereof. Background technique [0002] Cirrhosis is a common chronic, progressive, diffuse liver disease caused by different etiologies, and it is the final stage in the development of liver fibrosis. The symptoms of early liver cirrhosis are mild, such as poor appetite, nausea, vomiting, right upper quadrant pain, diarrhea and other symptoms; late stage is characterized by a series of complications induced by portal hypertension and liver insufficiency, including ascites, esophagogastric vein Variceal hemorrhage, hepatic encephalopathy, spontaneous peritonitis, hepatorenal syndrome and liver cancer. [0003] The scope of "hypochondriac pain" and "accumulation" of traditional Chinese medicine in the early stage of liver cirrhosis. Late often belongs t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/835A61P1/16A61K35/618
CPCA61K35/618A61K36/185A61K36/23A61K36/28A61K36/48A61K36/68A61K36/736A61K36/752A61K36/835A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 赵长普党中勤李鲜尹金磊袁帅强谢莉
Owner HENAN UNIV OF CHINESE MEDICINE
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