Endoscopic optical fiber Raman probe and detection device

Abstract

The invention discloses an endoscope fiber Raman probe and a detection device. The endoscope fiber Raman probe comprises a lens, a circular ring lens, a filtering layer, a circular ring filtering layer, a center optical fiber bundle, a Raman collection optical fiber, an optical fiber cable, a connecting piece, a center optical fiber bundle branch and a Raman collection optical fiber branch; the Raman collection optical fiber annually surrounds the center optical fiber bundle; the lens and the filtering layer are arranged at the front end of the center optical fiber bundle; the circular ring lens and the circular ring filtering layer are arranged at the front end of the Raman collection optical fiber; the combined optical fiber bundle of the Raman collection optical fiber and the center optical fiber bundle extends through the optical fiber cable; the other end of the optical fiber cable is divided into a Raman collection optical fiber bundle and an excitation / endoscope optical fiber bundle by the connecting piece. According to the endoscope fiber Raman probe disclosed by the invention, integrated design of optical fiber Raman and optical fiber endoscope is realized; the device hasthe advantages of small volume, low price, high flexibility and accurate detection, and is more applicable to biological in-vivo and in-situ Raman detection, and is relatively easy and convenient to maintain.

Description

technical field [0001] The invention belongs to the technical field of Raman spectrum detection, and in particular relates to a Raman spectrum measurement probe for in-situ detection of biological tissues and their lesions, and flexible monitoring of chemical reactions. Background technique [0002] Raman spectroscopy (Raman Spectroscopy) has been proved by theory and practice to be a powerful tool for medical detection and diagnosis from the molecular structure level. The molecular information carried by Raman spectroscopy can be used to distinguish cell and tissue types, as well as diseased and healthy tissues, and has begun to be more applied to the biomedical field. Raman spectroscopy also plays a complementary role with infrared spectroscopy, which can identify special molecular structure features or characteristic groups, so Raman spectroscopy is also widely used in chemistry, physics, materials science, environmental science and archaeology, etc. It has important sci...

AI Technical Summary

Problems solved by technology

The combined use of fiber optic Raman probes and endoscopes partially solves the problem that macroscopic and microscopic Raman systems cannot be directly used in in situ detection in the fields of biology and medicine

However, the combination of the probe and the endoscope increases the overall volume, which limits its application range; the actual Raman collection area of ​​the probe does not coincide with the endoscopic imaging area, which reduces the pertinence and accuracy of Raman spectrum collection

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