Application of resveratrol to preparation of drugs for treating or relieving chronic airway inflammation
A technology of resveratrol and airway inflammation, which is applied in the field of resveratrol used in the preparation of medicines for treating or alleviating chronic airway inflammatory diseases, and can solve the problem that resveratrol cannot effectively use chronic airway inflammation Diseases and other problems, to achieve the effect of reducing drug dosage, obvious curative effect, and increasing drug concentration
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[0023] The technical solutions of the present invention will be further described below in conjunction with examples and accompanying drawings.
[0024] The preparation method of the nebulizer containing resveratrol:
[0025] The resveratrol monomer was purchased from selleck company, and the preparation instruction shows: resveratrol (3-4'-5-trihydroxystilbene) is a non-flavonoid polyphenol compound with a molecular formula of C14H12O3 and a molecular weight of 228.24, -20 Stored at ℃ for three years, the appearance is colorless needle-like crystals, odorless, insoluble in water and ethanol, easily soluble in dimethyl sulfoxide (DMSO), melting point 256-258 ℃, sublimation temperature 261 ℃.
[0026] Resveratrol powder was added to DMSO to prepare 40 μg / μl resveratrol stock solution and stored at -20°C. The high-dose group (30mg / kg / d) atomized liquid preparation method is: 4.8ml normal saline + 0.12ml resveratrol stock solution; the medium-dose group (3mg / kg / d) atomized liqui...
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