Fast Calculation Method and System of Plaque Stability Index Based on Medical Image Sequence

A medical imaging and stability technology, applied in the field of medical devices, can solve the problems of heavy workload, complex realization, accumulation of errors, etc., and achieve the effect of comprehensive observation, high calculation efficiency, and better observation.

Active Publication Date: 2020-08-11
PULSE MEDICAL IMAGING TECH (SHANGHAI) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, based on the in vivo 4D vascular deformation behavior after 3D reconstruction at multiple times, there is a large workload and complex implementation, and there are certain errors or multiple times due to spatial transformations caused by multiple 3D reconstructions at different times. Disadvantages such as error accumulation
[0007] In addition, there is currently no rapid calculation method and system for obtaining two-dimensional lumen deformation parameters and corresponding plaque stability assessment based on medical image sequences

Method used

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  • Fast Calculation Method and System of Plaque Stability Index Based on Medical Image Sequence
  • Fast Calculation Method and System of Plaque Stability Index Based on Medical Image Sequence
  • Fast Calculation Method and System of Plaque Stability Index Based on Medical Image Sequence

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Embodiment 1

[0062] The present invention provides a fast calculation method for plaque stability indicators based on medical image sequences. The following uses a specific example to illustrate the rapid calculation method for plaque stability indicators in the present invention when coronary angiography image sequences are used as medical image sources. In this embodiment, taking the acquired sequence images of the anterior descending coronary artery as an example, those skilled in the art should understand that the blood vessel image data of a specific part is used here only as an example, and this specific part should not be taken as an example. Or blood vessels are understood as limiting the protection scope of the present invention.

[0063] In a specific embodiment, the method includes: using the image receiving module to read a two-dimensional contrast image sequence of the anterior descending coronary artery including a complete cardiac cycle; determining the starting and ending po...

Embodiment 2

[0086] In another specific embodiment, an algorithm for judging and evaluating plaque stability in the present invention is described in a specific application scenario.

[0087] Using the method of the present invention to analyze the periodic deformation of two-dimensional blood vessels to obtain the plaque stability index, that is, to calculate the data for judging the plaque stability, specifically, the method can be realized by the following steps:

[0088] In a specific embodiment, the maximum principal strain among the strain parameters of the diameter sequence of the stenotic segment of the lesion lumen is used as the specific index, and preferably, the maximum value and the average value reflect the dynamic periodic characteristics as the secondary result parameters. Of course, the specific indicators and secondary result parameters here can be adjusted and selected. For example, the maximum principal strain in the strain parameters can also be changed to the minimum p...

Embodiment 3

[0095] In yet another specific embodiment, the present invention also provides a rapid calculation system based on plaque stability indicators of medical image sequences provided by the present invention, the system comprising:

[0096] The image acquisition module is mainly used for image acquisition and generates dynamic image sequences;

[0097] The image receiving module is used to receive the image sequence generated by the image acquisition module and transmit it to the image processing module;

[0098] The image processing module processes the received image sequence; including the segmentation and registration of the lumen contour: the segmentation of the lumen contour includes the rapid segmentation of the normal lumen and the narrow lumen, and the lumen registration specifically refers to At different times, the displacement field function is generated by registering according to the feature space of the same vessel segment;

[0099] The plaque stability calculation...

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Abstract

The present invention provides a fast calculation method and system for plaque stability indexes based on medical image sequences. The system includes: an image collection and reception module, an image processing module, a plaque stability calculation module, and a result visualization module. The image acquisition and receiving module is used for the acquisition, reception and transmission of dynamic two-dimensional blood vessel image sequences; the image processing module is used for obtaining spatial transformation based on the dynamic information of the real-time deformation of the artery under the two-dimensional images, using local features or global images as registration The displacement field function; the plaque stability calculation module uses the above displacement field function to obtain the time-varying blood vessel diameter sequence, lumen centerline and contour deformation parameters and mechanical indicators through calculation. Based on the existing medical imaging functions, the present invention directly adds information such as time-varying blood vessel diameter sequence, lumen contour, and area strain and stress to the two-dimensional image, thereby simplifying and effectively realizing plaque stability. In vivo assessment.

Description

technical field [0001] The invention is applied in the field of medical devices, and in particular relates to an accurate, fast and non-invasive calculation method and system for the deformation behavior of the two-dimensional blood vessel lumen based on the medical image sequence, and the instantaneously variable lumen geometry and boundary contour strain parameters. Background technique [0002] At present, the commonly used clinical evaluation of vascular plaque mainly includes intravascular ultrasound, optical tomographic coherence imaging, X-ray contrast, CT contrast imaging and other imaging methods to determine the degree of stenosis of the two-dimensional lumen, plaque size and location and other information. However, many studies have shown that there is no direct relationship between the morphological indicators of plaque and the high risk of rupture. For example, the higher the narrowing rate of coronary artery diameter, the higher the incidence of plaque rupture. ...

Claims

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Application Information

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Patent Type & AuthorityPatents(China)
IPC IPC(8): G06T7/00G06T7/12G06T7/30
CPCG06T7/0012G06T7/12G06T7/30G06T2207/30101G06T7/33G06T2207/30104G06T2207/10016G06T2207/30172A61B5/02007A61B5/0037A61B5/7285G06T7/251G06T7/149G06T11/003
Inventor涂圣贤吴信雷张素黄佳悦
OwnerPULSE MEDICAL IMAGING TECH (SHANGHAI) CO LTD