Compound extracted from buerger lespedeza root as well as extraction process and application of compound

A compound, the technology of blood ginseng, which is applied in the field of extraction of active ingredients in blood ginseng, can solve the problems of insufficient, limited development and quality control of blood ginseng medicinal materials and their preparations, few types of active ingredients, etc.

Active Publication Date: 2018-07-13
贵州汉方药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For the research on the chemical components of blood ginseng, there are still relatively few active ingredients extracted from blood ginseng, mainly blood ginsenosides, blood ginseng subsides, etc. However, the active ingredients of blood ginseng are very complicated, and only these kinds of ingredients are Insufficient, still need to conduct in-depth research on the extraction process of blood ginseng to extract more active ingredients
Therefore, the active ingredients extracted by the existing blood ginseng extraction process are few, which limits the development and quality control of blood ginseng medicinal materials and their preparations

Method used

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  • Compound extracted from buerger lespedeza root as well as extraction process and application of compound
  • Compound extracted from buerger lespedeza root as well as extraction process and application of compound
  • Compound extracted from buerger lespedeza root as well as extraction process and application of compound

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Experimental program
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Embodiment 1

[0090] A compound extracted from blood ginseng, said compound is blood ginsenoside, and its structural formula is:

[0091]

[0092] The extraction method of described compound comprises the following steps:

[0093] (1) Blood ginseng roots are dried, crushed, and extracted twice with 6-8 times of 85-95% ethanol under reflux, each time for 2-4 hours, and the dregs are extracted with 5-6 times of 55-65% ethanol under reflux for 1.5-2.5 h, combine the three extracts, recover the solvent under reduced pressure until there is no ethanol smell, add 1-2 times the amount of water to the obtained concentrated solution to dilute and disperse, and obtain product A;

[0094] (2) Product A is extracted with ethyl acetate, and the solvent is recovered under reduced pressure to obtain ethyl acetate extract, and product B is obtained;

[0095] (3) Take the ethyl acetate extract, add 1.2-1.5 times the amount of 40-80 mesh silica gel to mix the sample, separate the mixed sample by 200-300 ...

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Abstract

The invention discloses a compound extracted from a buerger lespedeza root as well as an extraction process and application of the compound. The compound disclosed by the invention is separated from the buerger lespedeza root for the first time. The compound has anti-inflammatory action, can be used for preparing anti-inflammatory drugs, and is favorable for development and quality control of buerger lespedeza root medicines and preparations thereof.

Description

technical field [0001] The invention relates to an extraction method and application of effective components in blood ginseng, in particular to a compound extracted from blood ginseng and its extraction process and application. Background technique [0002] Blood ginseng is the root of Indigofera stachyodes Lindl, a plant of the leguminous family Indigo, which is a Miao medicine in Guizhou. It is also called iron brush, snow ginseng, mountain safflower, and red bitter thorn. Sweet, slightly bitter, warm in nature. It has the effects of nourishing yin and tonifying deficiency, regulating menstruation and taking blood, promoting blood circulation and relaxing tendons. Cure mainly metrorrhagia, chronic dysentery due to physical weakness, bleeding caused by intestinal wind, unrestrained ulcer, wind-damp arthralgia, bruises, liver cirrhosis, malnutrition, etc. It is a variety recorded in the "Quality Standards for Traditional Chinese Medicinal Materials and Ethnic Medicinal Mat...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07H15/18C07H1/08A61K31/7032A61P29/00
CPCC07H1/08C07H15/18
Inventor 张永萍傅建段丽梁光义张仕林姚厂发刘莉葛秋平
Owner 贵州汉方药业有限公司
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