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Cannula for minimizing dilution of dosing during nitric oxide delivery

一种氧化氮、套管的技术，应用在药物的器械、其他医疗器械、呼吸器等方向

Active Publication Date: 2018-08-03
MALLINCKRODT HOSPITAL PRODUCTS IP LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Delivering an accurate and consistent dose to a patient through a nasal cannula can be particularly challenging when the flow rate is pulsatile, for example, due to possible dose dilution

Method used

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  • Cannula for minimizing dilution of dosing during nitric oxide delivery
  • Cannula for minimizing dilution of dosing during nitric oxide delivery
  • Cannula for minimizing dilution of dosing during nitric oxide delivery

Examples

Experimental program
Comparison scheme
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Embodiment

[0292] refer to Figure 29 to Figure 30 , Figure 29 An example of reverse flow during inspiratory breathing and pulse delivery is shown, and Figure 30 An example of reverse flow during inhalation and exhalation breaths is shown.

[0293] refer to Figure 31 and Figure 32A , Figure 32B and Figure 32C , testing the reverse flow of various nasal cannula configurations. A typical nasal cannula delivered to both nostrils produced significant reverse flow, as shown in Test 1 of FIG. 31 . The nasal cannula configuration for Test 1 is shown in Figure 32A middle. For Test 2, the interconnection between the two nostrils was blocked to increase the distance between the nostrils to approximately 19 inches in an attempt to eliminate reverse flow. The nasal cannula configuration for Test 2 is shown in Figure 32B middle. Such as Figure 31 As shown in Test 2 of , although the overall volume of reverse flow can be reduced, it is not eliminated. Such as Figure 32C As sho...

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PUM

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Abstract

The present invention generally relates to, amongst other things, systems, devices, materials, and methods that can improve the accuracy and / or precision of nitric oxide therapy by, for example, reducing the dilution of inhaled nitric oxide (NO). As described herein, NO dilution can occur because of various factors. To reduce the dilution of an intended NO dose, various exemplary nasal cannulas, pneumatic configurations, methods of manufacturing, and methods of use, etc. are disclosed.

Description

[0001] This application is a PCT International Application with International Application No. PCT / US2013 / 073082, International Application Date December 4, 2013, and Invention Title "Cannula for Minimizing Dilution of Drug Administration During Nitric Oxide Delivery" A divisional application of the Chinese national phase patent application with the application number "CN 201380068828.4" after entering the Chinese national phase on June 29, 2015. technical field [0002] The present invention generally relates to improving the accuracy and / or precision of nitric oxide therapy, reducing dilution of inhaled nitric oxide, and / or ensuring intranasal mixing in a patient. Background technique [0003] Nitric oxide (NO) gas, when inhaled, dilates blood vessels in the lungs, oxygenating the blood and reducing pulmonary hypertension. Accordingly, some provide patients with pulmonary hypertension with nitric oxide in the form of an inhaled breathing gas containing a therapeutic gas. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M16/00
CPCA61M2202/0208A61M2202/0266A61M2202/0275A61M2202/0283A61M2205/75A61M2210/0618A61M16/101A61M16/122A61M16/125A61M16/204A61M2016/0021A61M2016/0027A61M16/0666A61M16/009A61M16/104A61M16/208A61M16/0672A61M16/0677A61M2205/3331A61M16/1005A61M2205/3303A61M2205/0216A61M16/10A61M16/0875
Inventor C·弗拉纳根S·弗里德J·克劳斯T·科尔曼M·D·麦格拉森M·奈杜P·沙阿
Owner MALLINCKRODT HOSPITAL PRODUCTS IP LTD
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