External application preparation containing tulobuterol pharmaceutical composition

A technology for external preparations and compositions, which is applied in the field of pharmaceutical preparations, and can solve problems such as the decrease in the solubility of synthetic rubber adhesives, the loss of active ingredients, and the impact on the efficacy of drugs
CN108403669AActive Publication Date: 2018-08-17BEIJING TIDE PHARMA
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
BEIJING TIDE PHARMA
Publication Date
2018-08-17

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Abstract

The present invention discloses an external application preparation containing a tulobuterol pharmaceutical composition, particularly a skin external application preparation containing a tulobuterol and crotamiton pharmaceutical composition. According to the present invention, by adding crotamiton, the solubility of tulobuterol is increased, the use of organic solvents is effectively avoided, theactive substance loss caused by the evaporation of the organic solvent is reduced, and the stability of the preparation is increased, such that the treatment effect of the drugs cannot be affected inthe case of the long-term storage while the environmental pollution is reduced, and the adverse reactions of the patient after the medication are reduced.
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Description

technical field

[0001] The invention relates to the field of pharmaceutical preparations, in particular to an external preparation for skin, in particular to an external preparation containing tulobuterol pharmaceutical composition and a preparation method thereof. Background technique

[0002] Tulobuterol (also known as clobuterol, Tulobuternl), is a selective beta 2 - Receptor agonist, which has a strong and long-lasting effect on dilating bronchial smooth muscle, but has a weak stimulating effect on the heart. It has certain anti-allergic effects, promotes bronchial cilia movement, and relieves cough and expectorant. It is used to relieve bronchial asthma, acute and chronic bronchitis, Emphysema, silicosis, pneumoconiosis

[0003] and other symptoms of respiratory obstruction. There has been great progress in the development of tulobuterol dosage forms. Aerosols, tablets, dry syrup, ointments, emulsions and patches of tulobuterol have been developed both at home and ab...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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