Application of a pharmaceutical composition in the preparation of antiviral drugs
A composition and drug technology, which can be used in drug combinations, antiviral agents, and resistance to vector-borne diseases, etc., can solve problems such as general antiviral efficacy, large side effects, and virus resistance.
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[0030] Further, the preparation method of the pharmaceutical composition comprises:
[0031] Mix the mixed medicinal materials formed by fennel fennel and spiny beans with 70-100% ethanol solution according to the ratio of solid to liquid: 1:15-25 and reflux extraction for 2-4 times, each time for 0.5-1.5h, concentrate the obtained extract, dry Dry.
[0032] Preferably, the temperature of reflux extraction is 60-80°C, or 65-75°C, or 70°C.
[0033] Preferably, the ratio of solid to liquid is 1:17~24, or 1:19~22, or 1:20.
[0034] Preferably, the concentration of the ethanol solution is 80-100%, or 90-100%, or 95%.
[0035] Preferably, extract 2~3 times, each time 0.8~1.2h; or extract 3 times, each time 1h.
[0036] This embodiment also provides a liquid preparation for treating viral upper respiratory tract infection, which is prepared by mixing the above pharmaceutical composition with sterile water to form a 5-500 g / L medicinal liquid and filtering it.
[0037] Preferably...
Embodiment 1
[0041] This embodiment provides a pharmaceutical composition, which comprises fennel fennel and Oxytropis falciparum at a mass ratio of 1:1.
[0042] The preparation method of this pharmaceutical composition comprises:
[0043] The fennel and Oxytropis falciparum were mixed at a mass ratio of 1:1, and mixed with 95% ethanol at a solid-to-liquid ratio of 1:20, and refluxed at 70°C for 3 times, 1 hour each time. The supernatant is recovered, concentrated, dried, and pulverized to obtain the obtained product.
Embodiment 2
[0045] The present embodiment provides a pharmaceutical composition, which comprises fennel and Oxytropis falciparum at a mass ratio of 1:5.
[0046] The preparation method of this pharmaceutical composition comprises:
[0047] Mix fennel and Oxytropis falciparum at a mass ratio of 1:5, and with absolute ethanol at a solid-to-liquid ratio of 1:15, and extract twice at 80°C under reflux, each time for 1.5h. The supernatant is recovered, concentrated, dried, and pulverized to obtain the obtained product.
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