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Prevention of endometrial carcinoma caused by endocrinotherapy after breast cancer operation by using radio frequency impedance

A technology of endocrine therapy and endometrial cancer, applied in parts of surgical instruments, surgery, medical science, etc., can solve problems that cannot be prevented in advance, achieve safe endocrine therapy, improve survival rate, reduce economic burden and psychological pressure Effect

Inactive Publication Date: 2019-02-22
嘉兴市妇幼保健院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most breast cancer postoperative patients who receive endocrine therapy regularly undergo uterine diagnostic dilatation and curettage, and then perform surgery after finding lesions, but it is often a passive treatment and cannot be prevented in advance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0012] The specific implementation of the present invention will be further described below in conjunction with the examples.

[0013] The endometrial ablation system formed by radio frequency impedance control technology, based on the principle of impedance control, uses radio frequency energy to vaporize the endometrium or the endometrium of the simulated uterus, the current flows through the tissue, and the impedance value between the electrode and the tissue changes with the treatment time. Increase, the elimination of endometrium continues to increase, as the tissue impedance continues to increase, when the impedance rises to 50Ω, that is, when the resection depth exceeds the superficial muscle layer, the device, that is, the radio frequency energy transmitter, automatically stops operating, indicating that the endometrium has been completely gasified , Elimination; In addition, the unique moisture transmission technology continuously removes the liquid and vaporized tissu...

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Abstract

The invention discloses prevention of endometrial carcinoma caused by endocrinotherapy after a breast cancer operation by using radio frequency impedance. Radio frequency energy is used to gasify theendometrium and gradually eliminate the endometrium; impedance measurement: the impedance value between an electrode and a tissue is measured, when the impedance rises to 50 omega, a signal is transmitted to a radio frequency energy emitter, and the radio frequency energy emitter stops emitting the radio frequency energy to complete elimination. Removing the endometrium by using the radio frequency impedance control technique can effectively prevent the risk of endometrial cancer of a breast cancer patient caused by long-term endocrine treatment after an operation. The results are verified bythe expression of tumor suppressor gene VHL, synuclein, and vascular endothelial growth factor and receptor thereof at home and abroad for the first time. Before long-term endocrine treatment is carried out on the breast cancer patient after the operation, carrying out a prevention scheme of removing the endometrium by using the radio frequency impedance control technique can effectively prevent the risk of endometrial cancer of the breast cancer patient caused by long-term endocrine treatment after the operation.

Description

technical field [0001] The invention relates to endometrial cancer, in particular to radio frequency impedance prevention of endometrial cancer caused by endocrine therapy after breast cancer surgery. Background technique [0002] In the past, when breast cancer patients were treated with endocrine drugs, for patients with obvious endometrium thickening or diagnostic curettage suggesting endometrial lesions, preventive hysterectomy was often taken, but data show that 30%-40% of hysterectomized women will Intraoperative complications or postoperative adverse reactions occur, 30% of hysterectomized women will suffer from psychosexual dysfunction and some other psychological diseases, not to mention the changes in the level of sex hormones in the body due to the loss of the uterus as the target organ of sex hormones, so , preventive hysterectomy has been difficult to be accepted by patients. [0003] Moreover, B-ultrasound monitoring and frequent diagnostic curettage are c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B18/12
CPCA61B18/12A61B2018/00559A61B2018/00595A61B2018/00702A61B2018/00875
Inventor 吴晓杰
Owner 嘉兴市妇幼保健院
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