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Sterilization composition for internal fistula puncture and application thereof

The technology of a composition and papaya extract, applied in the field of medicine, can solve the problems of inconvenience, long time, and long time consumption of medical staff, and achieve the effects of convenient operation, rapid absorption and onset of effect, and rapid absorption promotion.

Active Publication Date: 2019-03-08
ZHONGSHAN HOSPITAL XIAMEN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The process takes a long time, and the local anesthetic takes a long time to work, which brings great inconvenience to the medical staff

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] A kind of disinfectant solution for internal fistula puncture provided by the present embodiment comprises 1.95% of chlorhexidine gluconate, 2.4% of laurocapram, 3.2% of local anesthetic, 0.35% of borneol, and 2.8% of papaya extract according to weight percentage. %, ethanol 73%, water 16.3%.

Embodiment 2

[0039] A kind of disinfectant solution for internal fistula puncture provided by the present embodiment comprises 1.9% of chlorhexidine gluconate, 4.0% of laurocapram, 2.5% of local anesthetic, 0.4% of borneol, and 3.5% of papaya extract according to weight percentage. %, ethanol 70%, water 17.7%.

Embodiment 3

[0041]A kind of disinfectant solution for internal fistula puncture provided by the present embodiment comprises 2.1% of chlorhexidine gluconate, 3.0% of laurocapram, 3.0% of local anesthetic, 0.3% of borneol, and papaya extract 2% by weight percentage. %, ethanol 75%, water 14.6%.

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PUM

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Abstract

The invention provides a sterilization composition for internal fistula puncture and application thereof, and relates to the technical field of medicine. The sterilization composition for internal fistula puncture is prepared from the following ingredients in percentage by weight: 1.8 to 2.2 percent of chlorhexidine gluconate, 2.0 to 5.0 percent of laurocapam, 2.0 to 4.0 percent of local anesthetics, 0.1 to 0.5 percent of borneol, 1.2 to 3.8 percent of pawpaw extracts, 65 to 75 percent of ethanol and 10 to 25 percent of pharmacologically acceptable carriers. The sterilization composition contains chlorhexidine gluconate, ethanol and the like, and has the wide broad-spectrum bacteriostasis and sterilization effects; the added local anesthetics can achieve the surface anesthesia effect in the sterilization process; through the cooperated effect of borneol, laurocapam and pawpaw extracts, the adsorption of the skin to sterilization and narcotic ingredients can be accelerated; a good surface anesthesia effect can be achieved in 1 to 3 min; the adsorption effect taking speed is high; the composition can be used for the sterilization and anesthesia before the internal fistula puncture operation.

Description

technical field [0001] The invention relates to the field of medicine, and in particular to a disinfectant composition for internal fistula puncture and its application. Background technique [0002] Arteriovenous fistula is currently the most commonly used vascular access for maintaining hemodialysis, and it will bring different degrees of pain to patients during long-term puncture. The obvious pain of arteriovenous fistula puncture will not only bring great pain to patients, but also bring huge problems to clinical nursing work. Reducing the pain of internal fistula puncture can improve patients' treatment compliance and reduce the difficulty of post-care work. [0003] At present, local anesthetics are usually applied to patients to reduce pain during fistula puncture. The inventor found that when applying anesthesia, the puncture site needs to be sterilized first, then fixed on the puncture site with a sterile gauze block soaked in local anesthetic, and then disinfecte...

Claims

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Application Information

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IPC IPC(8): A61K36/732A61K9/08A61K47/22A61P23/02A61P31/02A61K31/045A61K31/155A61K31/167A61K31/191A61K31/245A61K31/445A61K31/4453
CPCA61K9/0014A61K9/08A61K31/045A61K31/155A61K31/167A61K31/191A61K31/245A61K31/445A61K31/4453A61K36/732A61K47/22A61P23/02A61P31/02A61K2300/00
Inventor 韩伟宗荣荣韩秋英杨小玲凌毅生关天俊
Owner ZHONGSHAN HOSPITAL XIAMEN UNIV
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