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A traditional Chinese medicine composition for preventing and treating chicken colibacillosis and its preparation method and application

A technology for chicken colibacillosis and composition, which is applied in the field of traditional Chinese medicine compositions and achieves the effects of rational formulation, convenient use and low toxicity

Active Publication Date: 2020-03-27
LUOYANG HUIZHONG ANIMAL MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Aiming at the current problem of bacterial resistance to western medicine and drug residues, the invention provides an effective traditional Chinese medicine composition, which can treat poultry diarrhea caused by pathogens such as Escherichia coli and environmental factors such as feeding and management. The traditional Chinese medicine composition is made Oral liquid or spray-dried to make powder or tablet to make granule dosage form, which is convenient for administration

Method used

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  • A traditional Chinese medicine composition for preventing and treating chicken colibacillosis and its preparation method and application
  • A traditional Chinese medicine composition for preventing and treating chicken colibacillosis and its preparation method and application

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Effect test

Embodiment 1

[0020] Embodiment 1: the preparation of Chinese medicine composition oral liquid of the present invention

[0021] The formula of Chinese medicine composition of the present invention is shown in Table 1.

[0022] Table 1 Concrete formula of traditional Chinese medicine composition

[0023] traditional Chinese medicine Composition 1 (serving) Composition 2 (parts) Composition 3 (parts) Pulsatilla 15 30 30 coptis 15 30 20 Scutellaria baicalensis 15 30 20 Myrobalan 15 15 15

[0024] 1. Weigh the traditional Chinese medicine according to the specific formula of the traditional Chinese medicine composition in Table 1, and see Table 2 for the weight of the ingredients.

[0025] Table 2 The weight of each component of the traditional Chinese medicine prescription

[0026] traditional Chinese medicine Composition 1 (g) Composition 2 (g) Composition 3 (g) Pulsatilla 100 115 141.2 coptis 100 115 94.1 ...

Embodiment 2

[0032] Embodiment 2: the preparation of Chinese medicine composition powder

[0033] 1. Weigh the traditional Chinese medicine according to the specific formula of the traditional Chinese medicine composition in Table 1.

[0034] 2. Pulsatilla, Coptidis, Scutellaria and Myrobalan are crushed and passed through a 60-mesh sieve.

[0035] 3. The above composition was soaked in a beaker of 2000ml distilled water for 6 hours, then placed in a water bath at 80°C for 12 hours, and then filtered.

[0036] 4. Add 2000ml of distilled water to the residue, put it in a water bath at 80°C for 6 hours, and concentrate to 800ml. Put it in an environment of 4°C, add 2400ml of 90% ethanol to the concentrated solution for ethanol precipitation for 24 hours, filter it with 6 layers of gauze, and take the supernatant.

[0037] 5. Concentrate the supernatant under reduced pressure and recover ethanol, and concentrate to 400ml.

[0038] 7. Spray-dry with a vacuum spray dryer, sub-package,.

Embodiment 3

[0039] Embodiment 3: the preparation of Chinese medicine composition granule

[0040] 1. Weigh the traditional Chinese medicine according to the specific formula of the traditional Chinese medicine composition in Table 1.

[0041] 2. Pulsatilla, Coptidis, Scutellaria and Myrobalan are crushed and passed through a 60-mesh sieve.

[0042] 3. The above composition was soaked in a beaker of 2000ml distilled water for 6 hours, then placed in a water bath at 80°C for 12 hours, and filtered through 4 layers of gauze.

[0043] 4. Add 2000ml of distilled water to the residue, put it in a water bath at 80°C for 6 hours, and concentrate to 800ml. Put it in an environment of 4°C, add 2400ml of 90% ethanol to the concentrated solution for ethanol precipitation for 24 hours, filter it with 6 layers of gauze, and take the supernatant.

[0044] 5. Concentrate the supernatant under reduced pressure and recover ethanol, and concentrate to 400ml.

[0045] 6. Add 2% gelatin and 2% β-cyclodextr...

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Abstract

The invention provides a traditional Chinese medicine composition, which comprises 10-30 parts of pasque flower, 3-30 parts of coptis, 3-30 parts of root of large-flowered skullcap and 5-15 parts of fructus chebulae. The traditional Chinese medicine composition has good treatment effect for intestinal infectious diseases due to pathogenic escherichia coli, salmonella and pasteurella multocida.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating poultry bacterial diseases, as well as its preparation method and application. Background technique [0002] As my country's breeding industry gradually develops towards scale, intensification, and modernization, there are still some problems at the same time, such as the incidence of livestock and poultry diseases is increasing year by year, and new diseases are increasing, especially diseases that endanger the safety of livestock and poultry. The trend of spreading has become an important obstacle that plagues my country's aquaculture industry. In particular, bacterial infections such as Escherichia coli, Salmonella, Pasteurella, and Staphylococcus are currently the most serious bacterial diseases that endanger aquaculture production, especially broiler production. Morbidity and mortality remain high, causing s...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/756A61K9/08A61K9/14A61K9/16A61P1/12A61P31/04
CPCY02A50/30
Inventor 张许科刘兴金张晓会
Owner LUOYANG HUIZHONG ANIMAL MEDICINE
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