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Traditional Chinese medicine composition for resisting liver cancer and preparation method of traditional Chinese medicine composition

A composition and anti-liver cancer technology, which can be used in drug combinations, anti-tumor drugs, pharmaceutical formulations, etc., can solve problems such as incompletely clear molecular mechanisms, and achieve improved anti-tumor effects, improved stability and bioavailability, and low cost. Effect

Inactive Publication Date: 2019-03-08
FOSHAN UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Western medicine is not completely clear about the etiology and exact molecular mechanism of primary liver cancer. At present, it is believed that its pathogenesis is a multi-factor and multi-step complex process, which is affected by environmental and therefore dual factors.

Method used

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  • Traditional Chinese medicine composition for resisting liver cancer and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for resisting liver cancer and preparation method of traditional Chinese medicine composition
  • Traditional Chinese medicine composition for resisting liver cancer and preparation method of traditional Chinese medicine composition

Examples

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Effect test

Embodiment 1

[0040] An anti-liver cancer traditional Chinese medicine composition, its raw material formula comprises the following components by weight:

[0041]

[0042] A preparation method of an anti-liver cancer Chinese medicine composition, the preparation method comprising the following steps:

[0043] 1) Wash and dry each raw material component as mentioned above to constant weight, and set aside;

[0044] 2) Take Selaginella sinensis washed and dried to constant weight, crush through a 40-mesh sieve, soak for 1 hour with 6 times the mass fraction of 75% ethanol aqueous solution, heat and reflux for extraction twice, each time for 1 hour, filter, and combine Extract solution, sonicate at 40°C for 10 minutes, add compound enzyme into the extract solution, heat in water bath at 55°C for 1 hour, inactivate enzyme at 90°C for 10 minutes, filter, use severag method to remove protein, and concentrate the solution to one-third of the original volume One, freeze-drying, drying, pulveri...

Embodiment 2

[0051] An anti-liver cancer traditional Chinese medicine composition, its raw material formula comprises the following components by weight:

[0052]

[0053] A preparation method of an anti-liver cancer Chinese medicine composition, the preparation method comprising the following steps:

[0054] 1) Wash and dry each raw material component as described in any item above to constant weight, and set aside;

[0055] 2) Take Selaginella sinensis washed and dried to constant weight, crush through a 50-mesh sieve, soak in 85% ethanol aqueous solution with 10 times the mass fraction for 2 hours, heat and reflux extraction 3 times, 2 hours each time, filter, and combine Extract solution, sonicate at 40°C for 10 minutes, add compound enzyme into the extract solution, heat in water bath at 55°C for 1 hour, inactivate enzyme at 90°C for 10 minutes, filter, use severag method to remove protein, and concentrate the solution to one-third of the original volume One, freeze-drying, drying...

Embodiment 3

[0062] An anti-liver cancer traditional Chinese medicine composition, its raw material formula comprises the following components by weight:

[0063]

[0064]

[0065] A preparation method of an anti-liver cancer Chinese medicine composition, the preparation method comprising the following steps:

[0066] 1) Wash and dry each raw material component as described in any item above to constant weight, and set aside;

[0067] 2) Take Selaginella sinensis washed and dried to constant weight, crush through a 50-mesh sieve, soak in 80% ethanol aqueous solution with 8 times the mass fraction for 2 hours, heat and reflux extraction 3 times, each time for 1.5 hours, filter and combine Extract solution, sonicate at 40°C for 10 minutes, add compound enzyme into the extract solution, heat in water bath at 55°C for 1 hour, inactivate enzyme at 90°C for 10 minutes, filter, use severag method to remove protein, and concentrate the solution to one-third of the original volume One, freez...

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Abstract

The invention discloses traditional Chinese medicine composition for resisting liver cancer. The composition comprises the following raw materials in parts by weight: 250-400 parts of herba selaginellae, 100-200 parts of ginseng, 50-100 parts of radix astragali, 20-80 parts of rhizoma curcumae longae and 50-100 parts of rhizoma anemarrhenae. Pure natural plant medicinal materials are adopted, andthe components are reasonably compatible, so that the anti-tumor effect is effectively improved, toxic and side effects are reduced, and immunity is improved; a very good anti-tumor effect can be realized by reasonable compatibility of the components, and the total effective rate is as high as 98%. The invention further provides a preparation method. The preparation method comprises the followingsteps: cleaning and drying the raw material components to constant weight, extracting the components one by one to obtain corresponding dry powder, and finally performing mixing to obtain a finished product. By extracting the effective components of the traditional Chinese medicine composition, stability and bioavailability of the composition are improved, absorption of the effective components inthe composition is facilitated, and various dosage forms can be prepared with a conventional traditional Chinese medicine preparation method. The composition has the advantages of good treatment effect, pure nature, low cost and the like, is safe and reliable, and can be taken by liver cancer patients for a long time.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for resisting liver cancer and a preparation method thereof. Background technique [0002] Liver cancer is a malignant tumor of the liver. It is a common and frequently-occurring disease in surgical diseases. Liver cancer can be divided into two categories: primary and secondary. Primary malignant tumors of the liver originate from the epithelial or mesenchymal tissues of the liver. The former is called primary liver cancer, which is a malignant tumor with a high incidence in my country and is extremely harmful; rare. Secondary or metastatic liver cancer refers to malignant tumors originating from multiple organs throughout the body and invading the liver. Generally, it is more common in liver metastases of malignant tumors in stomach, biliary tract, pancreas, colorectum, ovary, uterus, lung, breast and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P35/00
CPCA61K36/11A61K36/258A61K36/481A61K36/8964A61K36/9066A61P35/00A61K2300/00
Inventor 谢海青谢君毅
Owner FOSHAN UNIVERSITY
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