A detection kit for non-small cell lung cancer and its application

A non-small cell lung cancer and detection reagent technology, which is applied in the direction of measuring devices, microbial determination/inspection, instruments, etc., can solve the problems of complex detection mechanism, false positive, high sample requirements, etc., to overcome cumbersome operation and high specificity , good sensitivity
CN109722480BActive Publication Date: 2022-04-26SHANGHAI JIAOTONG UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
SHANGHAI JIAOTONG UNIV
Publication Date
2022-04-26

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Abstract

The invention belongs to the field of tumor biomarkers and tumor diagnosis, and in particular relates to a non-small cell lung cancer detection kit and application thereof. The present invention finds for the first time that FGF19 and β-klotho can be used individually or in combination as biomarkers for early diagnosis, selection of treatment options, and prognosis assessment of non-small cell lung cancer, with high specificity and good sensitivity. It can realize the early in vitro diagnosis of non-small cell lung cancer, overcome the limitation that most of the original non-small cell lung cancer detection is biopsy detection, and overcome the shortcomings of the existing non-small cell lung cancer serum detection that is cumbersome and has many false positives.
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Description

technical field

[0001] The invention belongs to the field of tumor biomarkers and tumor diagnosis, and in particular relates to a non-small cell lung cancer detection kit and application thereof. Background technique

[0002] Lung cancer can be divided into multiple tissue types according to different pathological characteristics. Different types of lung cancer have different treatment measures and prognosis effects. The histopathological classification of common lung cancer is divided into non-small cell carcinoma (NSCLC) and small cell carcinoma (SCLC). Non-small cell carcinoma is divided into squamous cell carcinoma (SCC), adenocarcinoma (AC) and large cell carcinoma (LCC), among which non-small cell lung cancer is the most common type of lung cancer, accounting for 80-85% of primary lung cancer . Once discovered, non-small cell lung cancer is generally in the middle and late stage, and the surgical treatment effect is not good. Therefore, the early diagnosis of non-sm...

Claims

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