Focal cartilage defect repair body

A prosthetic and cartilage technology, applied in the direction of joint implants, joint implants, etc., can solve the problems of long functional recovery time and reoperation, and achieve the effect of high matching degree, short time and high efficiency

Active Publication Date: 2019-05-10
重庆凝骄生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In view of this, the purpose of the present invention is to provide a restoration of focal cartilage defects, which can be used for commercialization of scaffolds through individualized 3D printing or processing, without the need for cell proliferation, and can be operated directly, with short operation time and high efficiency , to solve the problems of long functional recovery time and risk of reoperation in the prior art

Method used

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  • Focal cartilage defect repair body
  • Focal cartilage defect repair body
  • Focal cartilage defect repair body

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] Such as figure 2 As shown, a focal cartilage defect restoration is composed of a body 1 and a fixing nail 2. Both the body and the fixing nail can be directly processed, without cell transplantation and proliferation, and can be customized individually. :

[0041] The body is a double-layer structure composed of a cartilage layer 3 and a fixed layer 4;

[0042] The material of the cartilage layer is not limited, as long as it can make the cartilage layer have mechanical properties similar to the cartilage around the defect, ensure a certain viscoelasticity and compression modulus, and will not produce stress shielding or excessive compression during load bearing. Polyethylene or materials similar in physical properties to polyethylene, or a mixture of collagen and proteoglycan, etc.

[0043] The internal structure and materials of the fixation layer and fixation nails are not limited, as long as the fixation layer can withstand the physical impact of various joint activities...

Embodiment 2

[0060] Such as Image 6 and Figure 7 As shown, the difference from the first embodiment is that the body of this embodiment has a three-layer structure, specifically including a cartilage layer 3, a calcified layer 5, and a fixed layer 4. At this time, the calcified layer is a dense layer that connects the cartilage layer and fixes it. The role of the fixed layer, the fixed layer is a porous network structure, the porous network structure is easy to form a growth chamber, cartilage cells can enter the chamber to grow and proliferate, so that the body and articular cartilage are embedded and fixed. Better results.

[0061] In this embodiment, in order to improve the fixation effect, the calcified layer is connected to the cartilage layer and the fixation layer with special-shaped surfaces, and the special-shaped surfaces may be wave-shaped, tooth-shaped, or square-shaped. The shape of the joint surface between the calcification layer and the cartilage layer and the joint surface...

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Abstract

The invention relates to a focal cartilage defect repair body and belongs to the technical field of cartilage repair prosthesis. The repair body is composed of a main body and a fixing nail; the mainbody has the shape matched with those of the cartilage defect lumen and a defect area and physical characteristics the same as or similar to those of the cartilage defect; one end of the fixing nail is fixed with the main body, and the other end of the fixing nail extends out of the main body and is fixed with the subchondral bone of the defect lumen. By productizing the repair body, the whole operation is completed at a time without cell colonization or proliferation, the time is short, the efficiency is high, the precision and the accuracy are high, the problems of long function recovery time and risk of secondary operation in the prior art are solved, and the repair body has high practical value.

Description

Technical field [0001] The invention relates to the technical field of cartilage repair prostheses, in particular to a prosthesis used for joint function repair at articular cartilage defects. Background technique [0002] Articular cartilage has no blood vessels, cartilage cells cannot migrate, mature cartilage cells cannot proliferate and change the way of synthesis, which limits the cartilage's ability to repair itself. Therefore, once a cartilage defect occurs, it is basically unable to repair itself and requires external surgery to implant a cartilage stent for repair. [0003] Articular cartilage defects are common clinically. According to statistics, more than 60% of knee arthroscopic surgery patients have cartilage defects, of which 42% are focal hyaline cartilage defects, that is, the depth of the defect does not exceed the calcified cartilage layer, and the area of ​​the defect is 2 to 4 cm2 between. Because hyaline cartilage has no blood vessels, nerves and lymphatic s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/30
Inventor 王富友张玲
Owner 重庆凝骄生物科技有限公司
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