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A kind of tooth desensitization agent containing regenerative medicine material and preparation method thereof

A technology of medical materials and desensitizers, applied in medical science, pharmaceutical formulations, dental preparations, etc., to achieve the effects of eliminating dentin hypersensitivity, improving the oral environment, and enhancing biological activity

Active Publication Date: 2022-04-08
北京幸福益生高新技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] The main purpose of the present invention is to overcome the defects of existing tooth desensitizer products, and provide a new tooth desensitizer containing regenerative medical materials, preparation method and use method

Method used

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  • A kind of tooth desensitization agent containing regenerative medicine material and preparation method thereof
  • A kind of tooth desensitization agent containing regenerative medicine material and preparation method thereof
  • A kind of tooth desensitization agent containing regenerative medicine material and preparation method thereof

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preparation example Construction

[0080] The present invention also provides the preparation method of above-mentioned tooth desensitizing agent product, and described method is the technique of anhydrous vacuum high-speed shear dispersion, comprises the following steps:

[0081] Under the conditions of vacuum and high-speed shear dispersion, add matrix material, dispersant and gelling agent according to the formula, shear dispersion for 10-120 min, and stand for 60-120 min to obtain mixture A, and then add regenerative medical materials according to the formula and other ingredients, disperse under high-speed shearing for 10-120 minutes under vacuum conditions, and stand still for 10-60 minutes to obtain a tooth desensitizer product containing regenerative medical materials.

[0082] It should be noted that the vacuum and high-speed shear dispersing equipment used in the present invention are commonly used equipment in this field, and it is enough to realize the purpose of the present invention. The present in...

Embodiment 1-5

[0085] Weigh each raw material according to the formula of Example 1-5 in Table 1, with the raw material weighed, add matrix material, dispersant and gelling agent according to formula, shear and disperse, leave standstill, obtain mixture A, then according to formula Add regenerative medical materials and other ingredients, disperse under high-speed shearing under vacuum conditions, and let stand to obtain a tooth desensitizer product containing regenerative medical materials.

[0086]

Embodiment

[0087] Embodiment technical effect test:

[0088] In order to verify whether the tooth desensitizer product of the present invention reaches the expected inventive effect, the stability, pH, and tooth desensitization effect of the product prepared by the present invention are experimentally verified:

[0089] (1) Stability experiment

[0090] In order to verify the safety performance of the product of the present invention, the product of the present invention has been verified by a stability experiment.

[0091] Experimental method: Store in an oven at 50°C for 2 months, store at 4°C for two months, and store at room temperature for 6 months, and test the performance indicators of the products in Examples 1-5 respectively;

[0092] Table 2 Stability experiments in different environments

[0093]

[0094] It can be seen from Table 2 that after being stored in an oven at 50°C for 2 months, at 4°C for two months and at room temperature for 6 months, the tooth desensitizer p...

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Abstract

The present invention provides a tooth desensitizer product containing regenerative medicine material and a preparation method thereof; the tooth desensitizer product of regenerative medicine material is mainly made of the following raw materials: regenerative medicine material, matrix material, dispersant, gelling agent and Others; prepared by anhydrous vacuum high-speed shearing dispersion process. The present invention provides a tooth desensitizer product containing regenerative medical materials. The main functional components of the product are regenerative medicine materials, which can prevent and treat tooth hypersensitivity, and can also improve the oral environment. Caries has certain therapeutic and preventive effects.

Description

technical field [0001] The invention relates to the technical field of biomedical materials, in particular to a tooth desensitizer containing regenerative medical materials and a preparation method thereof. Background technique [0002] Dentin sensitivity refers to the short and sharp pain of exposed dentin to external stimuli, which cannot be attributed to other specific causes of tooth defects or lesions. Typical stimuli include thermal stimuli (hot and cold), chemical stimuli (acid sweet), mechanical stimulation (rubbing or biting hard objects), osmotic pressure, etc., which are characterized by rapid onset, sharp pain, and short duration. Dental hypersensitivity is not an independent disease, but a common symptom of various dental diseases. In 2008, the "Epidemiological Survey on Adult Dentin Sensitivity in my country" found that 29.7% of adults aged 20-69 had suffered from dentin hypersensitivity, and the highest incidence age was 50-59 years old, with a prevalence rat...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K6/831A61K6/838A61K6/80A61P1/02A61P31/02A61P37/08
Inventor 仇越秀胡方王菲刘小畅王健郭创洲许海华郑海霞殷昊
Owner 北京幸福益生高新技术有限公司
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