31 results about "Periodontal Disorder" patented technology

The invention provides genetic markers of periodontal disorders and/or periodontal diseases. The present invention provides methods and compositions to aid in the detection, diagnosis, treatment and monitoring of periodontal disorders and/or periodontal diseases.

The invention relates to sushuang (a brand) bioactivity mineral powder as well as a preparation method and application of the sushuang bioactivity mineral powder, and aims at solving the problems of unsatisfactory effect, tooth injury, high price and inconvenience for use in the conventional method for preventing decayed teeth and treating dentin hypersensitivity. The mineral powder is prepared by part or all of the following components: 35-55 parts of SiO2, 10-30 parts of CaO, 0.1-35 parts of K2O, 3-8 parts of P2O5, 0-20 parts of CaF2 and 0-30 parts of Na2O. The preparation method comprises the following steps of: melting the components at the temperature of 1350 DEG C, cooling, dewatering, and grinding. The mineral powder serves as an active constituent to be used for treating tooth and periodontal diseases to promote bone growth, and is convenient to use, good in treatment effect and moderate in price.

The present invention provides a novel composition of matter comprised of a mixture of two specific classes of compounds --Free-B-Ring flavonoids and flavans-- for use in the prevention and treatment of diseases and conditions associated with mouth, gums and teeth. This composition of matter simultaneously inhibits cyclooxygenase (COX) and lipoxygenase (LOX) enzymatic activity and reduces cytokine production at the mRNA level in normal, aged and damaged periodontal cells and tissues. This invention further provides a method for the prevention and treatment of diseases and conditions of the mouth, gums and teeth. The method for preventing and treating diseases and conditions of the mouth, teeth and gums is comprised of administering to a host in need thereof a therapeutically effective amount of a composition comprising a mixture of Free-B-Ring flavonoids and flavans synthesized and/or isolated from a single plant or multiple plants, preferably in the Scutellaria, Oroxylum, Acacia or Uncaria genus of plants and pharmaceutically and/or cosmetically acceptable carriers. Finally the present invention provides a method for the prevention and treatment of diseases and conditions of the mouth, teeth or gums, including but not limited to periodontal diseases, such as gingivitis, periodontitis, pulpitis, periodontal conditions caused by the physical implantation of oral dentures, trauma, injuries, bruxism, neoplastic and other degenerative processes; material alba, pellicles, dental plagues, calculus, and stains. Use of the composition described herein also affords the benefit of maintaining optimum saliva production and pH, minimizing bacterial growth, reducing the formation of pellicles and plague, inhibiting tooth decalcification and tooth caries (decay), promoting remineralization, which yields healthy gums, whitening teeth, maintaining healthy oral hygiene and reducing oral malodour (halitosis).

The invention relates to a production method and application of a nutgall effective part used for preventing and treating periodontal disease and inflammatory bowel disease. The production method is characterized by carrying out the following steps: taking a nutgall medicinal material; smashing the nutgall medicinal material; refluxing and extracting the smashed nutgall for 1-5 times in the presence of solvents (ethanol water and ethyl acetate), wherein extraction is carried out for 1-5 hours every time; mixing extract; carrying out column chromatography on the obtained mixed extract with polyamide resin or macroporous adsorption resin on exchange equipment; carrying out liquid chromatography-mass spectrometry determination and collecting fraction with the mass-to-charge ratio of 321 +/- 1and 635 +/- 1, and drying to thus obtain the nutgall effective part. The obtained nutgall effective part can strengthen teeth and gingival and is used for alleviating sore and weak teeth, chewing disability, looseness and displacement, gingival bleeding, mouth and tongue sores as well as swelling and pain in throat which are caused by the periodontal disease; and the nutgall effective part also can alleviate diarrhea and abdominal pain, mucus and bloody purulent stool as well as intestinal mucosal injury which are caused by the inflammatory bowel disease.

The invention relates to a functional toothpaste. The toothpaste contains natural plant active ingredients including bamboo leaf flavone, a thamnolia vermicularia extract, a snow lotus herb extract, arhodiola rosea extract and a lucid ganoderma extract, and natural mineral active ingredients including alabaster, edible salt, limonitum powder, turtleback gypsllill powder and limonite powder. According to the invention, due to addition of various active ingredients of natural medicinal plants/minerals, various oral and periodontal diseases can be prevented; meanwhile, the toothpaste enables teeth to be whiter under the condition that the tooth axis is not damaged, so bacteria on the surfaces of the teeth are effectively cleaned, and the situation that the bacteria and products of the bacteria endanger the health of surrounding organs is reduced; and experiment results prove that the functional toothpaste provided by the invention can well prevent and treat decayed teeth compared with common toothpaste.

The invention discloses manuka honey toothpaste for pregnant women. The toothpaste consists of the following components in parts by mass: 20-30 parts of water, 2-4 parts of coco-glucoside, 1-3 parts of manuka honey, 0.1-0.5 parts of borneol, 0.1-0.3 parts of an echinacea purpurea extract, 0.01-0.03 parts of tea tree oil and 30-60 parts of glycine. The invention further discloses a preparation method of the manuka honey toothpaste. The toothpaste disclosed by the invention contains New Zealand manuka honey, and with UMF in the manuka honey, the toothpaste has effects of resisting bacteria, resisting inflammation and preventing decayed teeth; the natural manuka honey, as a unique biological substance, is capable of preventing and repairing periodontal diseases; and the toothpaste disclosed by the invention, with the echinacea purpurea extract, fresh ginger oil and the tea tree oil which have an effect of sterilizing, can also improve immunity.

The invention provides application of magnesium hydride in preparation of a composition for preventing and treating chronic periodontitis, and magnesium hydride toothpaste. The weight percentage of magnesium hydride in the composition or the magnesium hydride toothpaste is 1-3%. The toothpaste has the effects of sterilizing, resisting inflammation, resisting oxidation, removing tooth stains, improving breath or halitosis, relieving redness, swelling and bleeding of gingiva and gingival recession, and improving periodontitis symptoms. The invention also discloses application of magnesium hydride in preparation of a composition for preventing and treating chronic periodontitis. According to the invention, a proper amount of magnesium hydride fine particles are added into the toothpaste body;and the magnesium hydride particles can be hydrolyzed into hydrogen and magnesium ions with an anti-inflammatory effect, and also can inhibit alveolar bone absorption. The composition containing magnesium hydride is safe to use, and can effectively prevent the occurrence and development of periodontal diseases after long-term use.

The invention belongs to the field of oral care products and concretely relates to toothpaste and a preparation technology thereof. According to the preparation technology, an oral care product is prepared by mixing a plurality of anti-inflammatory components, antibacterial ingredients and base ingredients, and by adding hydrogen peroxide and lysozyme, the bacterial microorganisms in the oral cavity can be fully killed. The oral care product has effects of preventing oral bacterium breeding and preventing and treating periodontal diseases. The anti-inflammatory components can solve oral problems of a user suffering from oral diseases to a certain extent.

A novel peptide and a composition including the peptide are disclosed. The composition may be a pharmaceutical composition, a quasi-drug composition, a dietary supplement, or a food composition. A polynucleotide encoding the peptide and an expression vector including the polynucleotide are also disclosed. The peptide promotes regeneration of hard tissue and is useful for treating dentin-dental pulp diseases or periodontal diseases.

The invention discloses a traditional Chinese medicine for preventing and treating periodontal diseases and a preparation process thereof. Through the direct action of the medicine and the combinationwith the medicine channel tropism and body meridian theory, pathological products which are accumulated around the periodontium and caused by pathogenic factors and other factors such as blood stasis, pathogenic fire and pathogenic cold can be completely discharged out of the body, thereby overcoming the defect that the existing symptomatic treatment method can realize temporary relief but can not achieve a prevention effect, and avoiding the dental discomfort caused by irritation of hot feeling, cold feeling, sour taste, sweet taste and the like. The traditional Chinese medicine disclosed bythe invention has the characteristics of simple preparation, convenient use, sufficient medicine source, low cost, high effect taking speed and no toxic and side effects, and is suitable for industrialized production.

The invention discloses a compound metronidazole tablet for pets, and a preparation method of the compound metronidazole tablet. The compound metronidazole tablet mainly comprises the following components in parts by weight: 20 parts of metronidazole, 15 parts of fenbufen, 40-60 parts of diluent, 3-10 parts of disintegrating agents, 2-5 parts of adhesives, 5-15 parts of phagostimulant and 0.25-2.0 parts of lubricants. The compound metronidazole tablet is suitable for the periodontal diseases, including gingivitis, periodontitis, gingival abscess, acute dental infection caused by clostridium and the like, of pets, has a good prevention and treatment effect and safe quality, is convenient for clinical medication of the pets, and has a good curative effect for the periodontal diseases caused by anaerobic infection of pets. After being used, the compound metronidazole tablet is good in oral absorption, and the bioavailability is 80% or above.

The invention relates to a traditional Chinese medicine composition for treating canine periodontal disease, which comprises the following components according to parts by weight: 1-50 parts of Chloranthus glaber, 1-50 parts of ophiopogon root, 1-50 parts of dandelion, 1-50 parts of umbellate pore furgus, 1-50 parts of dried orange peel, and 1-50 parts of Herba Oldenlandiae. The traditional Chinese medicine composition for treating canine periodontal disease has the beneficial effects that Chloranthus glaber has the effects of being anti-inflammatory, expelling wind and removing dampness, promoting blood circulation and stopping pain; ophiopogon root has the effects of nourishing yin and promoting production of body fluid; dandelion has the effects of clearing away heat and toxic material and removing swelling and stasis; and Herba Oldenlandiae has the effects of clearing away heat and toxic material, eliminating carbuncle and removing stasis and inducing diuresis to alleviate edema. According to combined action of Chloranthus glaber, ophiopogon root, dandelion, umbellate pore furgus, dried orange peel and Herba Oldenlandiae, the traditional Chinese medicine composition has the effects of clearing away heat and toxic material, nourishing yin and restoring qi; and the traditional Chinese medicine composition is capable of treating ngivitis and periodontitis, has good cleaning action on oral cavity, and is capable of treating and preventing canine periodontal disease.

The invention discloses a production process of toothpaste with functions of cleaning teeth, resisting inflammation and sterilizing. The toothpaste is prepared from the following raw materials: sorbitol, water, hydrated silica and polyethylene glycol-8; and the radix puerariae extract is added, and as many as 13 isoflavone substances contained in radix puerariae have a very good regulating effect on a human body, wherein the daidzein, daidzein, puerarin and other active substances have the functions of promoting blood flow of heart and cerebral vessels and retinas, relaxing smooth muscles, relieving spasm, resisting and promoting cancer, inducing cancer cell differentiation, reducing blood sugar, reducing blood pressure, resisting oxidation, clearing heat, dispelling the effects of alcohol, improving memory, enhancing immunity and the like, so that the dipotassium glycyrrhizinate has remarkable anti-inflammatory activity and can be used as a safe and efficient natural sweetening agent to replace sodium saccharin in the toothpaste, the sweetness of the dipotassium glycyrrhizinate is three hundred times that of sucrose, and the dipotassium glycyrrhizinate is healthier to use.