11 results about "Dentin hypersensitivity" patented technology

A dental varnish composition for promoting enamel remineralization may comprise nano-hydroxyapatite particles dispersed in a biocompatible resin matrix that forms an adhesive film on tooth enamel. The composition may include a solvent to facilitate uniform dispersion and one or more additives. The resin matrix may be hydrophilic to enhance adhesion and wetting of enamel microstructures. Contact with saliva triggers controlled, gradual release of nano-hydroxyapatite, providing sustained remineralization benefits and protection against demineralization over an extended period. The nano-hydroxyapatite may penetrate enamel microstructures and repair microlesions, while optionally reducing dentin hypersensitivity. The composition may be fluoride-free and formulated with defined weight ratios of resin, particles, and solvent. A method of treatment includes applying the varnish to tooth surfaces, forming the adhesive film, and allowing slow release of nano-hydroxyapatite to strengthen enamel.

The invention discloses a buccal element as well as a preparation method and application thereof, and belongs to the technical field of oral cleaning supplies. The method comprises the following steps: firstly, adding 2.8 to 3.5 parts of glacial acetic acid, 0.005 to 0.015 part of sodium benzoate, 0.005 to 0.015 part of sodium cyclamate, 0.08 to 0.12 part of lactic acid and 0.04 to 0.06 part of citric acid into 100 parts of water, and mixing to form acetic acid mother liquor; then, putting 3.7-4.6 parts of sodium bicarbonate and 0.08-0.12 part of calcium carbonate into a container, adding the acetic acid mother solution into the container, and stirring to form a mixed solution; adjusting the pH value of the mixed solution to 6.8-7.2, then sequentially adding 0.08-0.12 part by weight of lovastatin, 0.02-0.04 part by weight of peppermint water and 0.08-0.12 part by weight of a clove extracting solution, and uniformly stirring, so as to obtain the traditional Chinese medicine composition. The method disclosed by the invention is simple, and the prepared buccal essence is non-toxic and non-irritant, is high in decayed tooth inhibition rate and can quickly relieve decayed tooth pain and dentin hypersensitivity.

A composition for treating dentin hypersensitivity, comprising: a first component comprising: (i) a first rheology modifying polymer; (ii) a calcium ion source; (iii) a positively charged basic amino acid; and (iv) an acidifying agent, wherein the first component has a pH in the range of about 2.0 to about 7.0; a second component comprising: (i) a second rheology modifying polymer; (ii) a phosphate ion source; and (iii) an alkalizing agent, wherein the second component has a pH in the range of about 7.0 to about 14.0; wherein the first component and the second component are combined into a mixture such that a cationic amorphous calcium phosphate gel composition is created instantly when the pH of the mixture reaches a pH range of about 7.0 to about 9.5.

This invention discloses a highly antibacterial oral sealant for treating dentin hypersensitivity, its preparation method, and its application. The sealant's raw materials include calcium oxalate, diammonium hydrogen phosphate, tetraethyl orthosilicate, and cerium nitrate hexahydrate. It is a bioactive material that can generate hydroxyapatite in a short time and exhibits good biocompatibility. This sealant regulates and stabilizes Ce... 3+ Ce 4+ The ratio of these components results in high antibacterial properties, making it suitable for use as an oral sealant. It primarily works by sealing the gaps between the pits and fissures of teeth to block bacterial invasion, thereby improving the acid resistance of tooth enamel and preventing cavities. At the same time, this material has good bactericidal properties, allowing for deeper bacterial removal and ensuring a clean oral environment.

The invention discloses an integrated measuring system for evaluating the curative effect of dentin hypersensitivity. The integrated measuring system comprises a first applying module, a second applying module and a third applying module, the application force of the tactile stimulus is incremented at a preset gradient, and recording a tactile threshold of the patient representing an uncomfortable time; the second applying module applies cold air stimulation to the teeth of the patient; the temperature and the pressure of the cold air stimulation are controlled within a preset range, and the reaction score of the patient according to the Schiff cold air sensitivity scale is recorded; the association module associates the touch threshold with the reaction score to obtain comprehensive evaluation data; the acquisition module takes an initial touch threshold value and an initial reaction score obtained by measuring teeth of a patient for the first time or before treatment as baseline data; and the evaluation module obtains an evaluation result of the curative effect of the dentin hypersensitivity according to the comprehensive evaluation data and the baseline data. By simultaneously applying tactile stimulation and cold air stimulation, the one-sidedness of single stimulation evaluation is avoided, and the accuracy of evaluation of the curative effect of dentin hypersensitivity is improved.

This invention belongs to the field of biomaterials technology, specifically an antibacterial magnesium and strontium-reinforced bioactive glass ceramic and its applications. Its composition, by weight percentage, is as follows: SiO2: 30-50; P2O5: 5-20; CaO: 10-35; Na2O: 10-20; SrO: 5-20; MgO: 2-10; ZnO: 5-15; B2O3: 0-10; K2O: 3-10; CuO: 0.05-5; F: 1.5-5; Ag: 0.05-0.9. It possesses good biocompatibility, is non-toxic and harmless to the human body, and effectively inhibits and kills bacteria. It can be used as a special additive in oral care products such as toothpaste, mouthwash, tooth powder, tooth gel, and chewing gum, promoting tooth surface mineralization and reducing dentin hypersensitivity during the teeth cleaning process.

The present invention provides a composition useful for reducing dentin hypersensitivity, alleviating periodontitis, inhibiting halitosis, and promoting gingival recovery, the oral composition having an effect of inhibiting tooth sensitivity, improving periodontitis (decayed tooth), and can be effectively used in oral hygiene-related fields since it has an excellent effect of inhibiting halitosis.

This invention relates to a pharmaceutical composition for reducing dentin hypersensitivity and its preparation method, belonging to the field of biomedical technology. The pharmaceutical composition includes *Candida chinensis* extract, *Candida pubescens* leaf extract, eggshell membrane protein peptides, and *Bifidobacterium thermophilum* fermentation extract. The *Candida chinensis* extract is obtained by sequentially hydrolyzing *Candida chinensis* with a complex enzyme, ginger protease, and serrata peptides, followed by purification of the hydrolysate using an AB-8 macroporous resin column. The *Candida pubescens* leaf extract is obtained by ultrasonic extraction of *Candida pubescens* leaves with an ethanol-water solution, followed by purification of the extract using a composite packing adsorption column. The eggshell membrane protein peptides are obtained by co-hydrolyzing the eggshell membrane with ginger protease and fig protease, followed by purification of the hydrolysate using a G-25 dextran gel column. The *Bifidobacterium thermophilum* fermentation extract is obtained by purifying the fermentation broth of *Bifidobacterium thermophilum* using an SP agarose gel FF column. The components are combined in specific proportions for synergistic effects, achieving multi-functional and safe relief of dentin hypersensitivity.

This invention relates to the field of oral care, and particularly to an anti-dentin hypersensitivity mineralizing solution, its preparation method, and its application. The anti-dentin hypersensitivity mineralizing solution provided by this invention, on the one hand, due to the ultra-small size of the ions and ion clusters in the solution and its fluidity, ensures effective diffusion into the dentinal tubules after being coated on the dentin surface; on the other hand, when the mineralizing solution comes into contact with saliva or bodily fluids, it produces a biocompatible mineral—strontium-containing calcium phosphate stable by polyphosphate—which can block exposed dentinal tubules; moreover, the introduced strontium ions can passivate the nerve conduction of external stimuli, thereby alleviating the symptoms of tooth sensitivity; polyphosphate also provides certain antibacterial properties; strontium ions and polyphosphate can jointly regulate the mineralization properties of the mineralizing solution. Therefore, the anti-dentin hypersensitivity mineralizing solution provided by this invention can effectively prevent and treat dentin hypersensitivity and other symptoms related to tooth demineralization.

The present specification discloses a stabilized liquid composition of a peptide comprising an amino acid sequence represented by SEQ ID NO: 1. In particular, the present invention provides a composition that exhibits improved storage stability and handleability through adjustment of a pH range so that purity and the content of related substances meet the standards even under refrigerated and room-temperature conditions in a liquid state. Such a liquid composition is applied as a cosmetic, a quasi-drug, or a pharmaceutical product, and thus can provide a long-term shelf life while maintaining the original functionality of peptides for treating dentin hypersensitivity.

The present invention relates to compositions for use in oral care and various methods of their use. In particular, it relates to compositions comprising phosphoproteins and their use in the treatment and prevention of dentine hypersensitivity and the treatment and prevention of xerostomia. Preferred compositions comprise osteopontin and derivatives thereof.