12 results about "Osteoarthroses" patented technology

The invention provides a composition for improving bone joint health as well as a preparation method and application thereof, and relates to the technical field of bone joint health products. The composition for improving bone joint health is prepared from the following components in parts by mass: 0.5 to 5 parts of collagen peptide, 5 to 30 parts of mangosteen extract, 0.5 to 3 parts of non-denatured II type collagen peptide, 0.1 to 2 parts of milk mineral salt, 0.3 to 3 parts of bone collagen peptide, 0.1 to 2 parts of cartilage extract, 0.1 to 2 parts of N-acetylglucosamine, 0.1 to 2 parts of sodium hyaluronate and 0.3 to 3 parts of turmeric extract. The composition obtained by repeatedly compounding the mangosteen extract, the turmeric extract, the cartilage extract and the sodium hyaluronate has the advantages of low cost and high safety, and has a better effect on preventing or improving osteoarthrosis.

The invention provides a bone joint lesion recognition method and device based on multi-modal information fusion, electronic equipment and a computer readable storage medium. The bone joint lesion recognition method based on multi-modal information fusion comprises the following steps: acquiring a bone joint part image and text information; wherein the text information comprises bone joint questionnaire information and historical case information, and the bone joint questionnaire information comprises patient identity information and bone joint function evaluation information; performing image coding layer feature extraction on the bone joint part image to obtain image feature information; performing text coding layer feature extraction on the text information to obtain text feature information; performing multi-modal information fusion on the image feature information and the text feature information to obtain fused feature information; and bone joint lesion recognition is carried out based on the fusion feature information. According to the embodiment of the invention, the osteoarthropathy can be identified more accurately.

The invention discloses a plaster for treating osteoarthrosis and a preparation method thereof, and relates to the field of plasters for treating osteoarthrosis, and the plaster is prepared from the following raw materials: 14-18 parts of rhizoma atractylodis, 58-62 parts of garden balsam stem, 14-18 parts of cyathula officinalis, 8-12 parts of radix aucklandiae, 8-12 parts of gentiana macrophylla, 48-52 parts of clove root, 14-18 parts of cortex acanthopanacis, 8-12 parts of fructus cnidii, 98-102 parts of native copper, 14-18 parts of acorus gramineus, 8-12 parts of cinnamon, 48-52 parts of angelica sinensis and 48-52 parts of gastrodia elata. , 8-12 parts of Sichuan monkshood, 8-12 parts of pinellia ternate, 48-52 parts of myrrh, 48-52 parts of lycopodium clavatum, and 8-12 parts of dendrobe. The prepared plaster can be conveniently attached to the joint of a patient, stimulation of operations, anesthesia and the like is avoided, injury of the operations to the body is avoided, a series of toxic and side effects of oral medicines and the like are avoided, and the plaster is simple and effective to use; the cut plaster can be used for conveniently, simply, safely and effectively treating various osteoarthropathy such as cervical spondylosis, hyperostosis, lumbar disc herniation, rheumatism, rheumatoid, scapulohumeral periarthritis, arthritis, ankylosing spondylitis, fracture, traumatic injury and the like.

The present invention relates to a joint repair protein composition, and its preparation comprises the following steps: adding 20U / mL-35U / mL of any one or combination of nuclease or universal nuclease to a cell protein extract, placing it under 37°C±1°C for enzymolysis for 15min-40min, and separating and purifying the obtained enzymolysis solution. The cell protein composition obtained by the present invention has the effects of cell repair, joint repair, and cartilage repair, and is used for preventing and treating any one or complications of joint traumatic lesions, degenerative osteoarthritis, joint injuries, refractory wound lesions, knee osteoarthritis, and cartilage damage.

The invention relates to a tendon-stretching pain-relieving plaster, which is prepared by soaking a plurality of Chinese herbal medicines such as Aristolochia delavayi, Chinese actinidia root, herba aristolochiae, kadsura pepper stem, pseudo-ginseng and yellow lead in clear sesame oil and decocting into the plaster for external use, and the tendon-stretching pain-relieving plaster is mainly prepared from traditional Chinese medicines, has the effects of clearing away heat and toxic materials, diminishing inflammation and relieving pain, is low in cost, has the effects of dredging tendons and activating blood, dispelling wind and eliminating dampness, and stretching tendons and relieving pain, and is suitable for rheumatoid arthritis. The traditional Chinese medicine composition is free of side effects and good in curing effect, and can be used for treating osteoarthropathy such as rheumatic arthritis, osteoproliferation and traumatic injury.

The invention belongs to the technical field of medical instruments, and particularly relates to a knee osteoarthropathy AI acupoint electric diagnosis and treatment system which comprises a software architecture and a hardware architecture, the software architecture is composed of a medical platform, an applet and an equipment architecture, the software architecture further comprises a server, a front-end architecture, a background architecture, a data storage unit, a communication security unit, a data backup unit and a network connection unit, the hardware architecture comprises a system principle unit, a power management module, a man-machine interaction module, a driving algorithm unit and a structural design unit, and the software architecture is connected with the hardware architecture. According to the invention, a diagnosis and treatment scheme conforming to the patient is generated through the basic information and the disease information by using the independently researched and developed AI algorithm, and intelligent medical treatment is realized. All diagnosis and treatment schemes, patient information and disease features can be remotely stored, data information can be screened according to needs, doctors are helped to provide more comprehensive and detailed patient information, and therefore the treatment schemes can act on patients more directly and accurately, and efficiency is improved.

The utility model relates to a traditional Chinese medicine fumigating and washing device, in particular to an external traditional Chinese medicine fumigating and washing device for treating rheumatic osteoarthropathy, which comprises a boiling fumigating instrument, a movable connecting arm, a steam hose, a fumigating and washing cover, a mounting frame, an interactive clamping block and an elastic piece, the fumigation and washing cover is connected to the end, away from the boiling fumigation instrument, of the movable connecting arm, a steam hose is fixed to the movable connecting arm, one end of the steam hose is inserted and fixed into the boiling fumigation instrument, the other end of the steam hose is inserted and fixed to the fumigation and washing cover, and four mounting frames are symmetrically connected to the two sides of the top of the fumigation and washing cover. The two mounting frames on each side are each connected with an interaction clamping block in a sliding mode, and elastic pieces are connected between the mounting frames and the interaction clamping blocks. By designing the interactive clamping blocks and the elastic pieces, the towel is ensured to be stably fixed on the fuming and washing cover, and the problem that the towel is easy to fall off is effectively solved.

This invention discloses a neutralizing nanobody targeting soluble interleukin-17 receptor D (sIL-17RD), its preparation method, and its applications. The heavy chain variable region (VHH) of this nanobody contains a heavy chain complementarity-determining region 3 (CDR-H3) that specifically binds to sIL-17RD, with a length of 10 amino acids and containing 2–6 lysine residues. This invention provides four nanobodies: CQ5, CQ13, CQ11, and CQ6, corresponding to well-defined CDR-H1, CDR-H2, and CDR-H3 sequence combinations. This nanobody can specifically bind to and neutralize the biological activity of sIL-17RD, reducing chondrocyte death, promoting proliferation, and maintaining extracellular matrix homeostasis by inhibiting the P2rx7-NLRP3 inflammasome-mediated chondrocyte pyroptosis pathway. This invention also protects the nucleic acid encoding this nanobody, the recombinant expression vector, the host cell, the pharmaceutical composition, and the preparation method. The nanobodies described can be used to prepare drugs for the prevention and treatment of inflammatory osteoarthritis and other osteoarthritis. They can inhibit synovitis, reverse cartilage and subchondral bone degeneration, and relieve pain, showing promising application prospects.

The present invention discloses a traditional Chinese medicine composition, preparation, and preparation method for treating acute soft tissue injuries. The composition comprises the following raw materials: Chuanxiong, dried bone drynourish rhizome, clematis root, turmeric, earthworm, calcined copper, Panax notoginseng, Achyranthes bidentata, Zanthoxylum bungeanum, Sappan wood, safflower, vinegar frankincense, vinegar myrrh, dragon's blood, white mustard, borneol, menthol, and liquorice tablets. The composition has the effects of promoting blood circulation, dispersing blood stasis, reducing swelling and relieving pain. It can be applied externally to directly treat the affected area, rapidly penetrates the body, and quickly eliminates swelling and pain. It is an excellent topical analgesic ointment for treating swelling and pain caused by tendon and soft tissue injuries and osteoarthritis.

The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for improving osteoarthropathy and a preparation method and application thereof. The invention discloses a traditional Chinese medicine with the effects of tonifying liver and kidney, expelling wind-damp, dredging channels and collaterals and strengthening muscles and bones. The traditional Chinese medicine is mainly prepared from the following raw medicinal materials: radix puerariae, astragalus membranaceus, rhizoma drynariae, ginseng, Chinese yam, bighead atractylodes rhizome, pawpaw, eucommia ulmoides, angelica sinensis, ligusticum wallichii, notopterygium root, radix angelicae pubescentis, prepared rehmannia root, cistanche, zaocys dhumnade and radix achyranthis bidentatae. The channel tropism of the medicines in the formula is basically and directly related to the liver and the kidney, and the medicines are combined to achieve a good function of strengthening tendons and bones. Clinical research proves that the compound has a remarkable effect on dysfunction caused by osteoarthrosis, stasis-accumulating swelling and pain or muscle and bone injury and the like.

The present invention relates to a composition for intra-articular use in the treatment of osteoarthropathy (OA) comprising cross-linked hyaluronic acid or a salt or derivative thereof, clodronate or an equivalent salt thereof, and an acetate buffer.

The invention discloses an acupoint positioning model for osteoarthropathy traditional Chinese medicine suitable technology training, and particularly relates to the technical field of medical models.The acupoint positioning model comprises a base, a rotating mechanism and a fixing frame are sequentially arranged on the base, a moving mechanism is arranged on one side of the fixing frame, a lifting mechanism is installed above the fixing frame, and an inner supporting assembly is connected between the moving mechanism and the lifting mechanism; the leg joint model is covered outside the inner support assembly, through cooperation of the lifting mechanism and the moving mechanism, the leg joint model can bend and stretch, changes of knee acupuncture points in different stretching states of leg joints are simulated, multi-angle display is achieved in combination with the rotating mechanism, training of the angle and depth of needle application and acupuncture point explanation is facilitated, the leg joint model is made of a silica gel material, and the sense of reality is improved. The stability and the safety are enhanced through the design of the supporting plates and the flanges of the base. The model effectively improves the training effect of the traditional Chinese medicine suitable technology for osteoarthropathy.