Device and synthesis method for continuously synthesizing 4-bromo-2-p-chloro-5-trifluoromethyl pyrrole-3-nitrile

Abstract

The invention provides a device for continuously synthesizing 4-bromo-2-p-chloro-5-trifluoromethyl pyrrole-3-nitrile, which comprises a first circulating pump, a first plate type heat exchanger, a second circulating pump, a second plate type heat exchanger and an oscillating flow spiral baffle reactor which are sequentially communicated, wherein the oscillating flow spiral baffle reactor comprisesa shell with an accommodating space, a raw material inlet and a raw material outlet provided in the shell and a baffle plate erected in the accommodating space; the baffle plate is a baffle board; two ends of the baffle plate are respectively communicated with the raw material inlet and the raw material outlet; the baffle plate cuts the accommodating space into a continuous bending structure. Compared with the related art, the device for continuously synthesizing 4-bromo-2-p-chloro-5-trifluoromethyl pyrrole-3-nitrile has the advantages that the reaction time is short; the reaction process iseasy to control with less by-products and high product yield.

Description

【Technical field】 [0001] The invention relates to a reactor, in particular to a device and a synthesis method for continuously synthesizing 4-bromo-2-p-chloro-5-trifluoromethylpyrrole-3-carbonitrile. 【Background technique】 [0002] 4-Bromo-2-p-chloro-5-trifluoromethylpyrrole-3-carbonitrile is an important intermediate of arylpyrrole insecticides and acaricides chlorfenapyr and chlorfenapyr, the main synthesis method is 2 -(4-Chlorophenyl)-5-trifluoromethylpyrrole-3-carbonitrile and bromine are synthesized by bromination reaction. [0003] Batch synthesis is generally adopted in industry. This process has the advantages of simple operation and low cost, but at the same time, it has disadvantages such as slow reaction speed, excessive raw material bromine required, more waste acid produced, and greater safety risks. [0004] Therefore, it is necessary to provide a new device and synthesis method for continuously synthesizing 4-bromo-2-p-chloro-5-trifluoromethylpyrrole-3-carbo...

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Problems solved by technology

[0005] The technical problem to be solved in the present invention is that the reaction speed in the batch synthesis of 4-bromo-2-p-chloro-5-trifluoromethylpyrrole-3-carbonitrile in the prior art is relatively slow, the raw material bromine needs to be excessive, and waste acid is produced. The present invention provides a device for continuously synthesizing 4-bromo-2-p-chloro-5-trifluoromethylpyrrole-3-carbonitrile

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