Chinese patent medicine for treating laryngitis and preparation method thereof

A kind of Chinese patent medicine, the technology of laryngopharynx, it is applied in the Chinese patent medicine I in the treatment of larynx and its preparation field, can solve the problems such as lack of systematic, scientific clinical research data, not to collect adverse reactions etc.

Inactive Publication Date: 2019-06-25
EYE & ENT HOSPITAL SHANGHAI MEDICAL SCHOOL FUDAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chinese patent medicine I has been in clinical use for more than 30 years. Patients respond well and the curative effect is positive, and no adverse reactions caused by this medicine have been collected.
However, although doctors and patients affirm the drug, there is no systematic and scientific clinical research data of the drug

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] A Chinese patent medicine for treating sore throat (including acute and chronic laryngitis), comprising the following Chinese medicinal materials in parts by weight: 562.5 g of Scrophulariae Radix Scrophulariae, 187.5 g of Bean Root, 375 g of Honey Aster, 375 g of Phellodendron Phellodendri, 187.5 g of Platycodon grandiflorum, and 187.5 g of Cicada slough , licorice 187.5g. Add distilled water to decoct the Qiwei herbs twice, add 8 times the amount of water for the first time, add 6 times the amount of water for the second time, filter each time for 1.5 hours, combine the filtrates, let stand overnight, take the supernatant, and concentrate To the extract with a relative density of 1.13-1.15 (70°C), take the extract and add an appropriate amount of dextrin, stir evenly, spray dry, granulate, dry below 80°C, make 1000g, pack it separately, and get it. The patient took it with boiled water, 8g each time, twice a day. 14 days is a course of treatment. During the period of...

Embodiment 2

[0022] A Chinese patent medicine for treating sore throat (including acute and chronic laryngitis), comprising the following Chinese medicinal materials in parts by weight: 750 g of Scrophulariae Radix Scrophulariae, 375 g of Bean Root, 562.5 g of Honey Aster, 375 g of Cortex Phellodendri, 375 g of Platycodon grandiflorum, 375 g of Cicada slough, and 375 g of Licorice . Add distilled water to decoct the Qiwei herbs twice, add 8 times the amount of water for the first time, add 6 times the amount of water for the second time, filter each time for 1.5 hours, combine the filtrates, let stand overnight, take the supernatant, and concentrate To the extract with a relative density of 1.13-1.15 (70°C), take the extract and add an appropriate amount of dextrin, stir evenly, spray dry, make tablets, dry below 80°C, make 1000g, pack it separately, and get it.

Embodiment 3

[0024] A Chinese patent medicine for treating laryngitis (including acute and chronic laryngitis), comprising the following Chinese medicinal materials in parts by weight: 937.5 g of Scrophulariae Radix Scrophulariae, 375 g of Bean Root, 562.5 g of Honey Aster, 562.5 g of Phellodendron Phellodendri, 375 g of Platycodon grandiflorum, and 187.5 g of Cicada slough , licorice 375g. Add distilled water to decoct the Qiwei herbs twice, add 8 times the amount of water for the first time, add 6 times the amount of water for the second time, filter each time for 1.5 hours, combine the filtrates, let stand overnight, take the supernatant, and concentrate To the extract with a relative density of 1.13-1.15 (70°C), take the extract and add an appropriate amount of dextrin, stir evenly, spray dry, make capsules, dry below 80°C, make 1000g, and pack it separately.

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PUM

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Abstract

The invention discloses a Chinese patent medicine for treating laryngitis (including acute and chronic laryngitis), wherein the Chinese patent medicine is composed of radix scrophulariae, subprostratesophora, honeyed aster, golden cypress, platycodon grandiflorum, cicada slough and liquorice. Through randomized, open and positive medicine parallel controlled clinical experiments, the change of hoarseness assessment GRBSA (the total score of total hoarseness grade, asthenia and breathiness) scores and the change of subjective perception scores are analyzed after 143 patients with laryngitis (including acute and chronic laryngitis) take the Chinese patent medicine I or a control medicine randomly, and the validity of the Chinese patent medicine I is determined. The safety of the Chinese patent medicine I is determined by laboratory examination, electrocardiogram examination and analysis of adverse reaction conditions before and after the tests on the patients. The results show that theChinese patent medicine I has remarkable curative effect on laryngitis, is obviously superior to the control group, has good safety, and is worth popularizing and using in clinic.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, in particular to a Chinese patent medicine I for treating laryngitis (including acute and chronic laryngitis) and a preparation method thereof. Background technique [0002] Throat pain (including acute and chronic laryngitis) is mostly caused by wind-heat, wind-cold attack, lung insufficiency, damp-heat obstruction, phlegm-qi intertwined, guest in the glottis, or loss of veins after throat surgery, stagnation of qi and blood, Manifested as hoarseness or even aphonia, accompanied by burning pain in the throat, examination shows redness and swelling of vocal cords, hypertrophy or formation of polyp nodules, etc. [0003] Western medicine often adopts local nebulization inhalation anti-inflammatory treatment or oral antibiotic treatment. Local aerosol inhalation anti-inflammatory treatment is gentamicin + dexamethasone. Oral antibiotic therapy is oral levofloxacin or amoxicillin. How...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/808A61P11/04A61P29/00
Inventor 陈念祖吴海涛黄滔敏闫晶超沈剑文
Owner EYE & ENT HOSPITAL SHANGHAI MEDICAL SCHOOL FUDAN UNIV
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