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Use of mistletoe extract in preparing traditional Chinese medicine products for improving the activity of ovarian granulosa cells

A technology of granulosa cells and mistletoe, which is applied in the field of preparing traditional Chinese medicine products to improve the activity of ovarian granulosa cells by mistletoe extract

Active Publication Date: 2022-04-01
INST OF BOTANY JIANGSU PROVINCE & CHINESE ACADEMY OF SCI +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no report on the use of mistletoe extract in the preparation of ovary nourishing preparations to improve the activity of ovarian granulosa cells

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Example 1: Preparation of aqueous extract

[0015] Will mever alert to the sieve, add 8 times water soaked, heat reflow to extract 2-4 hours, and the solid dry powder obtained by concentrating the reduced pressure of the extract is a mistletoe extract.

Embodiment 2

[0016] Example 2: Preparation of sunlet extract

[0017] Will mever and pulverize the sieve, add 10 times water soaking, heat reflow to extract 2-4 hours, and the solid drying powder obtained by concentrating the reduced pressure under reduced pressure is a mistletoe extract.

Embodiment 3

[0018] Example 3: Preparation of sunlet extract

[0019] Watching the parasitic drying herbal material and crushed the sieve, adding 12 times water soaking, heat reflowing for 2-4 hours, and the solid dry powder obtained by concentrating concentrated under reduced pressure is a mistletoe extract.

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PUM

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Abstract

The invention discloses the use of mistletoe extract in the preparation of traditional Chinese medicine products for improving the activity of ovarian granulosa cells. According to the pathogenesis of ovarian dysfunction and insufficient growth of ovarian granulosa cells, the present invention makes full use of traditional Chinese medicine resources, and on the basis of preparing mistletoe extract, through pharmacological experiments, develops the effect of mistletoe extract on treating ovarian dysfunction and improving ovarian granulosa. A new use in cell activity, the extract can be added to products of different dosage forms to achieve the activity of nourishing the ovary by promoting the proliferation of ovarian granulosa cells and increasing the secretion level of estrogen and progesterone in ovarian granulosa cells. It is clinically used to treat ovarian cancer It has the advantages of good curative effect, small side effects, and convenient use.

Description

Technical field [0001] The present invention belongs to the field of traditional Chinese medicine, and specific involves new uses of mistletoe extracts in the preparation of the addition of ovarian pellet cell active Chinese medicine products. Background technique [0002] The physiological functions of ovaries include ovulation and endocrine function, which is of great significance for women's reproductive function, physical and mental health and quality of life. Ovarian dysfunction can cause ovulation dysfunction, abnormal yellow body function and endocrine disorders, thereby causing a variety of gynecological diseases, such as uterine development, infertility, ovarian failure, peripheral syndrome, etc., and can affect all other dirty The physiological function of the device. [0003] The ovarian is an important source of reproductive organs in the female animal reproductive system. It has two important roles. One is to produce ripe eggs, and the second is secreted steroid horm...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/185A61K36/815A61K36/232A61K36/638A61K36/39A61K36/43A61P15/08A61K135/00A61K127/00
CPCA61K36/185A61K36/815A61K36/232A61K36/638A61K36/39A61K36/43A61P15/08A61K2236/331A61K2236/51A61K2300/00
Inventor 宋萍萍毛艳韦敏姜晓雁吕晔钱怡云颜露
Owner INST OF BOTANY JIANGSU PROVINCE & CHINESE ACADEMY OF SCI
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