Combination product containing limonoid and alpha-glucosidase inhibitor

A technology of glycosidase inhibitors and limonoids, which is applied in the field of medicine and can solve problems such as elevated liver enzymes, aggravated diseases, and injuries
CN110327356AActive Publication Date: 2019-10-15NATURAL MEDICINE INST OF ZHEJIANG YANGSHENGTANG
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
NATURAL MEDICINE INST OF ZHEJIANG YANGSHENGTANG
Publication Date
2019-10-15

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Abstract

The invention relates to a combination product containing limonoid (and a derivative, ester, a stereoisomer, salt or prodrug acceptable in pharmacy of the limonoid) and an alpha-glucosidase inhibitor(such as acarbose, acarbose derivative, voglibose, miglitol and the like). The invention further relates to application of the combination product containing the limonoid and the alpha-glucosidase inhibitor in treating and / or preventing diabetes-related diseases.
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Description

technical field

[0001] The invention belongs to the technical field of medicine, in particular to a limonoid compound (and pharmaceutically acceptable derivatives, esters, stereoisomers, salts or prodrugs thereof) and an alpha-glucosidase inhibitor (or its Combination products of pharmaceutically acceptable derivatives). The present invention also relates to the use of the combined product in treating and / or preventing diabetes and diseases related to metabolic syndrome. Background technique

[0002] According to IDF statistics, there were about 425 million people with diabetes worldwide in 2017, and 1 in every 11 people has diabetes. The number of diabetic patients in China is about 110 million, ranking first in the world. It is predicted that by 2040, there will be 642 million people with diabetes worldwide, and 151 million people with diabetes in China. Diabetes requires lifelong monitoring and treatment. If it is not well controlled, it will lead to secondary cardiova...

Claims

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