Systems, devices, and methods for delivery of pulsed electric field ablative energy to endocardial tissue

A technique of grouping pulses and pulse waveforms is applied in the field of systems, devices and methods for delivering pulsed electric field ablation energy to endocardial tissue, and can solve the problem of not satisfying damage prevention devices and the like

Active Publication Date: 2020-01-07
BOSTON SCI SCIMED INC
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] While pulsed DC voltages can drive electroporation under appropriate circumstances, there remains an unmet need for thinner, flexible atraumatic devices that efficiently deliver high DC voltage electroporation ablation therapy selectively to endocardial tissue in the area of ​​interest while minimizing damage to healthy tissue

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  • Systems, devices, and methods for delivery of pulsed electric field ablative energy to endocardial tissue
  • Systems, devices, and methods for delivery of pulsed electric field ablative energy to endocardial tissue
  • Systems, devices, and methods for delivery of pulsed electric field ablative energy to endocardial tissue

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Embodiment Construction

[0057]Described herein are systems, devices, and methods for the selective and rapid application of pulsed electric fields to ablate tissue by irreversible electroporation. In general, the systems, devices, and methods described herein can be used to generate large electric field magnitudes in desired regions of interest and reduce peak electric field values ​​elsewhere to reduce unnecessary tissue damage and arcing. The irreversible electroporation system described herein may comprise a signal generator and a processor configured to apply one or more voltage pulse waveforms to a selected set of electrodes of an ablation device to induce the Energy is delivered regionally (eg, ablative energy for a group of tissues in the ostia of the pulmonary veins). The pulse waveforms disclosed herein can aid in the treatment of various cardiac arrhythmias (eg, atrial fibrillation). To deliver the pulse waveform generated by the signal generator, one or more electrodes of the ablation dev...

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Abstract

Systems, devices, and methods for electroporation ablation therapy are disclosed, with the device including a set of splines coupled to a catheter for medical ablation therapy. Each spline of the setof splines may include a set of electrodes formed on that spline. The set of splines may be configured for translation to transition between a first configuration and a second configuration. Each spline of the set of splines in the second configuration may be petal shaped.

Description

[0001] Cross References to Related Applications [0002] This application is part of U.S. Patent Application Serial No. 15 / 874,721, filed January 18, 2018, and entitled "SYSTEMS, DEVICES, AND METHODS FOR FOCAL ABLATION" Continuation of application claiming the benefit of US Provisional Application Serial No. 62 / 529,268, filed July 6, 2017, and entitled "Systems, Apparatus, and Methods for Focal Ablation." This application is also required to be filed on September 21, 2017 and is entitled "SYSTEMS, DEVICES, AND METHODS FOR DELIVERY OF PULSED ELECTRIC FIELD ABLATIVE ENERGY TOENDOCARDIAL TISSUE)" U.S. Patent Application No. 15 / 711,266 filed January 4, 2017 and entitled "System for Delivery of Pulsed Electric Field Ablation Energy to Endocardial Tissue , Apparatus and Methods" PCT Application No. PCT / US2017 / 012099, filed January 5, 2016 and entitled "For the Delivery of Pulsed Electric Field Ablation Energy to Endocardial Tissue System, Apparatus, and Apparatus for ” U.S. Provisio...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00A61B5/042A61B5/0432
CPCA61B18/12A61B18/1492A61N1/056A61N1/327A61N1/362A61B2018/00351A61B2018/00357A61B2018/1407A61B2018/0016A61B2018/00375A61B2018/00613A61B2018/00267A61B2018/00839
Inventor R·维斯瓦纳萨安A·齐恩格勒尔G·朗J-L·帕雅尔B·哈谢伊
Owner BOSTON SCI SCIMED INC
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