Chinese medicinal composition with hypoglycemic effect, preparation method and application thereof

A composition and a hypoglycemic technology, applied in the field of medicine, can solve the problems of exhaustion, disease, incurable, etc.

Active Publication Date: 2020-04-14
蔚龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinically, hyperglycemia is the main feature. In typical cases, symptoms such as polyuria, polydipsia, polyphagia, and weight loss may occur, namely "three excesses and one deficiency". Once diabetes (blood sugar) is not well controlled, it will cause complications and lead to , eyes, feet and other parts of the failure of the lesion, and can not be cured

Method used

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  • Chinese medicinal composition with hypoglycemic effect, preparation method and application thereof
  • Chinese medicinal composition with hypoglycemic effect, preparation method and application thereof
  • Chinese medicinal composition with hypoglycemic effect, preparation method and application thereof

Examples

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Comparison scheme
Effect test

Embodiment 1

[0034] A traditional Chinese medicine composition with hypoglycemic effect, which is made of the following components in parts by weight: 100g of watermelon, 30g of Fructus aurantii and 20g of willow fish;

[0035] The preparation method of the traditional Chinese medicine composition comprises the following steps: S1: Weigh the above-mentioned components and various ingredients in proportion, grind them into 300-mesh granules after fully cleaning; , Carry out reflux extraction at 50°C for 2 hours to obtain the ethanol extract, then recover the solvent from the ethanol extract under reduced pressure at 40°C until dry to obtain the extract; S3: Adsorb the extract on AB-8 macropores The resin was allowed to stand for 30 minutes, and then eluted with pure water, followed by gradient elution with 10%, 20%, 40%, and 60%, 75% and 90% aqueous ethanol, collecting 60%, 75% and 90% % ethanol aqueous solution eluted fractions, and after combining, the solvent was recovered under reduced ...

Embodiment 2

[0037] A traditional Chinese medicine composition with hypoglycemic effect, which is made of the following components in parts by weight: 200g of watermelon, 90g of Fructus aurantii and 60g of willow fish;

[0038] The preparation method of the traditional Chinese medicine composition comprises the following steps: S1: Weigh the above-mentioned components and various medicines in proportion, grind them into 500-mesh granules after fully cleaning; S2: add the above-mentioned granules to 90% v / v ethanol aqueous solution , Carry out reflux extraction at 70°C for 30min to obtain ethanol extract, then decompress the ethanol extract at 60°C to recover the solvent until dry to obtain the extract; S3: Adsorb the extract on AB-8 macropore The resin was allowed to stand for 2 hours, firstly eluted with pure water, and then sequentially eluted with 10%, 20%, 40%, and 60%, 75% and 90% ethanol aqueous solution to collect 60%, 75% and 90% The fractions eluted with % ethanol aqueous solution...

Embodiment 3

[0040] A traditional Chinese medicine composition with hypoglycemic effect, which is made of the following components in parts by weight: 120g of watermelon, 50g of Fructus aurantii and 30g of willow fish;

[0041] The preparation method of the traditional Chinese medicine composition comprises the following steps: S1: Weigh the above-mentioned ingredients and medicines in proportion, grind them into 400-mesh granules after fully cleaning; S2: add the above-mentioned granules with a concentration of 70% v / v ethanol aqueous solution 1. Carry out reflux extraction at 60°C for 1 hour to obtain an ethanol extract, then recover the solvent at 50°C from the ethanol extract and dry it under reduced pressure to obtain the extract; S3: Adsorb the extract on AB-8 macropores The resin was allowed to stand for 1 hour, and then eluted with pure water, followed by gradient elution with 10%, 20%, 40%, and 60%, 75% and 90% ethanol aqueous solution, collecting 60%, 75% and 90% % ethanol aqueous ...

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Abstract

The invention provides a Chinese medicinal composition with hypoglycemic effect, a preparation method and application thereof. The Chinese medicinal composition is prepared from the following drugs byweight: 10-20 parts of nymphoides peltatum, 3-9 parts of fructus aurantii and 2-6 parts of linaria vulgaris. The Chinese medicinal composition with hypoglycemic effect is prepared by he steps of cleaning, superfine grinding, ethanol reflux extraction, macroporous resin separation and the like, can significantly lower the blood glucose index and postprandial blood glucose of diabetic patients, andcan reach the effects of controlling illness state, delaying disease course development and preventing complications.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine composition with hypoglycemic effect, a preparation method and application thereof. Background technique [0002] Diabetes (diabetes) is a sugar, protein, Syndrome of a series of metabolic disorders including fat, water and electrolytes. Clinically, hyperglycemia is the main feature. In typical cases, symptoms such as polyuria, polydipsia, polyphagia, and weight loss may occur, namely "three excesses and one deficiency". Once diabetes (blood sugar) is not well controlled, it will cause complications and lead to , eyes, feet and other parts of the failure of the disease, and can not be cured. The long-term high blood sugar in diabetes leads to chronic damage and dysfunction of various tissues, especially the eyes, kidneys, heart, blood vessels, and nerves. [0003] Diabetes belongs to the category of "diabetes" in traditional Chinese ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/80A61P3/10
CPCA61K36/51A61K36/752A61K36/80A61P3/10A61K2236/333A61K2236/55A61K2300/00
Inventor 蔚龙
Owner 蔚龙
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