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Blood collection tube for medical clinical examinations and preparation method thereof

A technology for clinical testing and blood collection, which is applied in the field of medical clinical testing and can solve problems such as environmental pollution, poor anticoagulation effect, and poor bacteriostatic effect.

Pending Publication Date: 2020-05-05
湖北金杏科技发展有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Aiming at the deficiencies of the prior art, the present invention provides a blood collection tube for medical clinical examination and its preparation method, which solves the problem that the blood collection tube is generally made of non-degradable materials, and the degradation speed is slow, causing pollution to the environment and There are problems of poor antibacterial effect and poor anticoagulant effect

Method used

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  • Blood collection tube for medical clinical examinations and preparation method thereof
  • Blood collection tube for medical clinical examinations and preparation method thereof
  • Blood collection tube for medical clinical examinations and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] S1. Preparation of the first mixture: 10 parts of sodium citrate, 14 parts of sodium citrate, 20 parts of glyceraldehyde and 15 parts of magnesium stearate were put into the stirring tank, and the temperature inside the stirring tank was raised to 160°C. Stirring under conditions, uniform stirring at a speed of 350r / min for 1h, when stirring until there is no precipitation or crystallization, turn off the power switch of the stirring tank to stop stirring, and then adjust the pH to 5 to obtain the first mixture and wait for standby;

[0029] S2. Preparation of the second mixture: put 14 parts of polyvinyl alcohol and 12 parts of diquaternary ammonium salt into the mixer, mix evenly for 20 minutes, then add 16 parts of polylactic acid and 20 parts of ethanol, and heat the mixer to 80°C. Then stir and mix for 5 minutes, so that 20 parts of ethanol and the mixed material are fully dissolved and evenly formed into a milky mixture, and the pH value is adjusted to 5 to obtain ...

Embodiment 2

[0034] S1. Preparation of the first mixture: 11 parts of sodium citrate, 15 parts of sodium citrate, 21 parts of glyceraldehyde and 16 parts of magnesium stearate were put into the stirring tank, and the temperature inside the stirring tank was raised to 180°C. Stirring under the same conditions, uniformly stirring at a speed of 400r / min for 1.2h, when stirring until there is no precipitation or crystallization, turn off the power switch of the stirring tank to stop stirring, and then adjust the pH to 5.5 to obtain the first mixture and wait for standby;

[0035] S2. Preparation of the second mixture: put 15 parts of polyvinyl alcohol and 14 parts of diquaternary ammonium salt into the mixer, and mix uniformly for 25 minutes, then add 18 parts of polylactic acid and 22 parts of ethanol, and heat the mixer to 90°C. Then stir and mix for 6 minutes, so that 22 parts of ethanol and the mixed material are fully dissolved and evenly formed into a milky mixture, and the pH value is ad...

Embodiment 3

[0040] S1. Preparation of the first mixture: 12 parts of sodium citrate, 16 parts of sodium citrate, 22 parts of glyceraldehyde and 18 parts of magnesium stearate were put into the stirring tank, and the temperature inside the stirring tank was raised to 200°C. Stir under the same conditions, uniformly stir at a speed of 450r / min for 1.5h, when stirring until there is no precipitation or crystallization, turn off the power switch of the stirring tank to stop stirring, and then adjust the pH to 6 to obtain the first mixture and wait for standby;

[0041] S2. Preparation of the second mixture: put 16 parts of polyvinyl alcohol and 15 parts of diquaternary ammonium salt into the mixer, and mix uniformly for 30 minutes, then add 18 parts of polylactic acid and 25 parts of ethanol, and heat the mixer to 100 ° C. Then stir and mix for 8 minutes, so that 25 parts of ethanol and the mixed material are fully dissolved and evenly formed into a milky mixture, and the pH value is adjusted ...

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Abstract

The invention discloses a blood collection tube for medical clinical examinations, and relates to the technical field of medical clinical examinations. The blood collection tube comprises a tube body,wherein the top of the tube body is movably connected with a safety cap, a rubber plug is fixedly connected between two sides of the inner wall of the safety cap, and the bottom of the rubber plug runs through the tube body and extends to the inside the tube body. According to the invention, through adopting polylactic acid and polyvinyl alcohol as the main materials for the preparation of the blood collection tube, the biodegradable ability of the blood collection tube can be accelerated, and the blood collection tube is much faster in degradation speed than conventional blood collection tubes on the market, causing no pollution to environment after the blood collection tube is abandoned; meanwhile, the antibacterial ability of the blood collection tube can be greatly improved by using anti-bacterial agents and bis-quaternary ammonium salts, and a cooperated use of sodium citrate and sodium citrate can play a good anti-coagulation role; the above-mentioned materials adopted in the invention are common materials on the market, so that the economic cost is lower; and the invention establishes a basis for the accuracy of subsequent blood test results.

Description

technical field [0001] The invention relates to the technical field of medical clinical testing, in particular to a blood collection tube for medical clinical testing and a preparation method thereof. Background technique [0002] Vacuum blood collection tube is a disposable negative pressure vacuum glass tube that can realize quantitative blood collection. It needs to be used together with venous blood collection needle. The principle of vacuum blood collection tube is to pre-pump the blood collection tube with a cap to different vacuum , using its negative pressure to automatically and quantitatively collect venous blood samples. One end of the blood collection needle is inserted into the human vein and the other end is inserted into the rubber plug of the vacuum blood collection tube. The human venous blood is drawn into the vacuum blood collection tube under the action of negative pressure. The blood sample container can realize multi-tube collection without leakage unde...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/154B29B7/00B29B9/06B29C43/02B29C43/58
CPCA61B5/154A61B5/15003B29B7/002B29B9/06B29C43/02B29C43/58B29C2043/5816B29L2031/712
Inventor 杨柯
Owner 湖北金杏科技发展有限公司
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