Anticancer pharmaceutical composition and preparation method thereof
A composition and drug technology, applied in the field of medicine, can solve the problems of insignificant therapeutic effects of chemical drugs, easy to produce drug resistance, and large toxic and side effects, and achieve the effects of regulating tumor immune metabolism, changing the growth microenvironment, and reducing toxic and side effects
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[0053] The embodiment of the present invention also provides a preparation method of an anticancer pharmaceutical composition, comprising the following steps:
[0054] S10. Obtain the Chinese herbal medicine in the formula amount, pulverize it, and obtain the Chinese herbal medicine powder;
[0055] S20. Add the fermented vinegar in the formula amount to the Chinese herbal medicine powder for soaking treatment, and then stir-fry with a slow fire to obtain a stir-fried product with a slow fire;
[0056] S30. The fermented fermented unstrained spirits and vinegar paste obtained in the formula amount are added to the product stir-fried with slow fire and mixed, and then fermented to obtain a fermented product;
[0057] S40. Adding water with a ratio of 3 to 9 times the weight of raw materials to the fermentation product, extracting and processing to obtain an anti-cancer pharmaceutical composition, the anti-cancer pharmaceutical composition comprising: an anti-cancer extract and ...
Embodiment 1
[0073] An embodiment of the present invention provides an anticancer pharmaceutical composition, which specifically includes the following steps:
[0074] 1. Preparation of fermented product
[0075] 1) Mix, grind, and soak raw materials sorghum and rice, and steam the raw materials that have fully absorbed water for 120 minutes, then add 180% water of raw materials to the steamed raw materials, stew for 60 minutes, and stew at a temperature of 100°C;
[0076] 2) Grind Moutai Daqu, add 50% of the weight of the raw materials into the raw materials and mix well, then add 60% of the raw materials in water, ferment in tanks for 3 days at a fermentation temperature of 15-40°C, seal and age for 360 days after preliminary fermentation, Obtain primary fermented product;
[0077] 3) Add 150% of the weight of raw materials to the first-stage fermentation product, mix evenly, divide it into shallow tanks, cover it with straw mats, ferment for 10 days, turn it layer by layer every day, a...
Embodiment 2
[0099] An embodiment of the present invention provides an anticancer pharmaceutical composition, which specifically includes the following steps:
[0100] 1. Preparation of fermented seed grains
[0101] 1) Mix, grind, and soak the raw materials sorghum and rice, and steam the raw materials that have fully absorbed water for 180 minutes, then add 150% water by weight of the raw materials to the steamed raw materials, and stew for 30 minutes at a temperature of 100°C;
[0102] 2) Pulverize Luzhou Daqu, add 40% of the weight of the raw materials into the raw materials and mix well, then add 70% of the raw materials in water, ferment in tanks for 3 days at a fermentation temperature of 15-40°C, seal and age for 180 days after preliminary fermentation, Obtain primary fermented product;
[0103] 3) Add 120% of the raw material weight of grain leather to the primary fermentation product, mix evenly, divide it into shallow tanks, cover it with a straw mat, ferment for 15 days, and t...
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