An in vitro simulated digestion box

An in vitro simulation and box technology, applied in teaching models, instruments, educational appliances, etc., can solve the problems of expensive instruments, complicated operations, and huge instruments, and achieve the effects of simple equipment, good reproducibility, and easy control of conditions.

Active Publication Date: 2022-03-18
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the instrument is very large and requires a large number of samples to carry out related experiments, and the instrument is expensive and complicated to operate

Method used

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  • An in vitro simulated digestion box
  • An in vitro simulated digestion box
  • An in vitro simulated digestion box

Examples

Experimental program
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Embodiment Construction

[0019] Such as figure 1 , the present invention provides an in vitro simulated digestion box, comprising sequentially connected stomach digestion parts, small intestine digestion parts and large intestine digestion parts; Digestive fluid inlet 1, gastric digestive fluid inlet 2, sampling port 3, and gastric digestion sample outlet 4; the intestinal digestive fluid inlet 1 and gastric digestive fluid inlet 2 are arranged on one side of the gastric digestive component, and the sampling port 3 and gastric The digestion sample outlet 4 is set on the other side of the gastric digestion part; the gastric digestive liquid inlet 1 and the sampling port 3 are located on the lower assembly of the gastric digestion part, and the gastric digestive liquid inlet 2 and gastric digestion sample outlet 4 are located on the stomach digestion part. On the upper assembly of the component; a polycarbonate film is provided between the upper assembly and the lower assembly of the gastric digestion c...

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Abstract

The invention discloses an in vitro simulated digestion box, which comprises sequentially connected stomach digestion parts, small intestine digestion parts and large intestine digestion parts; the stomach digestion parts are riveted and connected by an upper assembly and a lower assembly; liquid inlet, stomach digestive juice inlet, sampling port and stomach digestion sample outlet; the small intestine digestion part is connected by riveting of the first component and the second component, and the small intestine digestion part includes a sample inlet, a stomach digestion sample inlet, an intestinal digestion sample Outlet and intestinal digestion sample sampling port, the large intestine digestion part is riveted connection by the third component and the fourth component, and the large intestine digestion part includes an intestinal digestion sample inlet, a cell culture medium inlet, a digestion and absorption sample outlet, and a metabolic digestion sample outlet and polycarbonate film. The in vitro simulated digestion box has a stable structure and good reproducibility; the equipment is simple and the conditions are easy to control.

Description

technical field [0001] The invention belongs to the technical field of in vitro complete digestive tract simulation, and in particular relates to an in vitro simulated digestion box, which reflects the digestion of soluble nutrients by the human digestive tract. Background technique [0002] The ingredients in food are complex. In the process of digestion, different nutritional ingredients have different changes. Different nutritional ingredients have different mechanisms for producing physiological activities. The mechanism by which physiological activity is produced will change. Polyphenols, carotenoids, vitamins and polysaccharides will all change during digestion, thereby affecting the expression of their physiological activities (Food Chemistry, 2006, 102(3), 865-874; FoodHydrocolloids, 2016, 58, 171-178; British Food Journal, 2008 110(3), 296-309; Journal of Agricultural & Food Chemistry, 2006, 54(23), 8749-8755). [0003] In order to detect the changes of nutrients ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G09B23/28
CPCG09B23/28
Inventor 叶兴乾陶文扬陈士国
Owner ZHEJIANG UNIV
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