A kind of nano silicon dioxide coated quaternary ammonium salt chitosan composite antibacterial agent and preparation method thereof

A quaternary ammonium salt chitosan, nano-silica technology, applied in the directions of botanical equipment and methods, biocides, disinfectants, etc., can solve the problems of antibacterial application limitation, insufficient thermal performance, difficult to add, etc., to achieve antibacterial properties, inhibiting bacterial growth, reducing the effect of degradation

Active Publication Date: 2022-04-08
LIMING VOCATIONAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, as an organic polymer material, quaternary ammonium chitosan itself has insufficient thermal properties and is difficult to add to plastic substrates, and its antibacterial application is limited.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] The raw material ratio (parts by weight) of the nano-silica coated quaternary ammonium chitosan composite antibacterial agent of the present embodiment is as follows: 1 part of quaternary ammonium chitosan aqueous solution, 1 part of liquid paraffin, Span-80 emulsification 0.3 parts of agent, 5 parts of polyvinyl alcohol aqueous solution, and 5 parts of tetraethyl orthosilicate solution. Among them, the degree of substitution of quaternary ammonium chitosan is 50-90%, the relative molecular mass is 100,000-800,000, and the solid content of the quaternary ammonium chitosan solution is 2%; The solid content of the vinyl alcohol aqueous solution is 3%; the ratio by weight of tetraethyl orthosilicate, ethanol and deionized water in the tetraethyl orthosilicate solution is 3:10:10.

[0027] The nano silicon dioxide coated quaternary ammonium chitosan composite antibacterial agent of the present embodiment is prepared according to the following steps:

[0028] Step 1. Disper...

Embodiment 2

[0038] The raw material ratio (parts by weight) of the nano-silica coated quaternary ammonium chitosan composite antibacterial agent of the present embodiment is as follows: 1 part of quaternary ammonium chitosan aqueous solution, 2 parts of liquid paraffin, emulsified by Span-60 0.3 parts of agent, 5 parts of polyvinyl alcohol aqueous solution, and 5 parts of tetraethyl orthosilicate solution. Among them, the degree of substitution of quaternary ammonium chitosan is 50-90%, the relative molecular mass is 100,000-800,000, and the solid content of the quaternary ammonium chitosan solution is 5%; the relative molecular mass of polyvinyl alcohol is 100,000, and the polyvinyl alcohol The solid content of the vinyl alcohol aqueous solution is 5%; the ratio by weight of tetraethyl orthosilicate, ethanol and deionized water in the tetraethyl orthosilicate solution is 3:10:10.

[0039] The nano silicon dioxide coated quaternary ammonium chitosan composite antibacterial agent of the pr...

Embodiment 3

[0050] The raw material ratio (parts by weight) of the nano-silica coated quaternary ammonium chitosan composite antibacterial agent of the present embodiment is as follows: 1 part of quaternary ammonium chitosan aqueous solution, 2 parts of liquid paraffin, Span-80 emulsification 0.6 parts of agent, 10 parts of polyvinyl alcohol aqueous solution, and 8 parts of tetraethyl orthosilicate solution. Among them, the degree of substitution of quaternary ammonium chitosan is 50-90%, the relative molecular mass is 100,000-800,000, and the solid content of the quaternary ammonium chitosan solution is 10%; The solid content of the vinyl alcohol aqueous solution is 6%; the ratio by weight of tetraethyl orthosilicate, ethanol and deionized water in the tetraethyl orthosilicate solution is 3:10:10.

[0051] The nano silicon dioxide coated quaternary ammonium chitosan composite antibacterial agent of the present embodiment is prepared according to the following steps:

[0052] Step 1. Dis...

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Abstract

The invention discloses a nano-silica-coated quaternary ammonium chitosan composite antibacterial agent and a preparation method thereof. The antibacterial agent comprises the following components in parts by weight: 1-3 parts of quaternary ammonium chitosan aqueous solution , 1-4 parts of liquid paraffin, 0.1-1.0 parts of emulsifier, 5-15 parts of polyvinyl alcohol aqueous solution, and 5-15 parts of tetraethyl orthosilicate solution. Preparation method: add quaternary ammonium chitosan aqueous solution into liquid paraffin dissolved with emulsifier and mix to form water-in-oil emulsion, transfer the emulsion to polyvinyl alcohol aqueous solution and mix to form water / oil / water emulsion, then add orthosilicic acid The tetraethyl ester solution is mixed evenly, and then a certain amount of alkaline solution is added dropwise, so that the silica precipitates to form a gel and precipitates and adheres to the quaternary ammonium chitosan, and is crushed, washed, and dried to obtain nano-silica coating Quaternary ammonium chitosan compound antibacterial agent. The antibacterial agent has good antibacterial performance and thermal performance.

Description

technical field [0001] The invention relates to a composite antibacterial agent, in particular to a nano silicon dioxide-coated quaternary ammonium chitosan composite antibacterial agent and a preparation method thereof. Background technique [0002] Quaternary ammonium chitosan is a derivative of chitosan modified by quaternary ammonium salt. Compared with chitosan, its water solubility is greatly improved. With the increase of substitution degree, it can swell even in neutral water environment. Dissolved, the quaternary ammonium salt group in the molecule can exert antibacterial effect. However, quaternary ammonium chitosan, as an organic polymer material, has insufficient thermal properties and is difficult to add to plastic substrates, and its antibacterial application is limited. Contents of the invention [0003] The invention provides a method for preparing a nano-silica-coated quaternary ammonium chitosan composite antibacterial agent. Through the construction of ...

Claims

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Application Information

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Patent Type & AuthorityPatents(China)
IPC IPC(8): A01N25/08A01N25/22A01N43/16A01P1/00C08L29/04C08L5/08C08L91/06C08K3/36
CPCA01N25/08A01N25/22A01N43/16C08L29/04C08K2201/011C08L2205/03C08L5/08C08L91/06C08K3/36
Inventor曾安蓉林鸿裕汪扬涛曾安然
OwnerLIMING VOCATIONAL UNIV