A preparation method of three-dimensional porous graphene film and its microfluidic chip

Abstract

The invention relates to the technical field of microfluidic chips, and specifically discloses a preparation method of a three-dimensional porous graphene film and a microfluidic chip thereof. After dispersing carbon-doped titanium dioxide nanofibers in pure ethanol and ultrasonically treating them, they are combined with photosensitive Acrylate matrix and photoinitiator are added to the graphene oxide hydrosol after ultrasonic treatment, and after ultrasonic treatment again, the preparation of the required solid three-dimensional structure is produced by projection micro-stereolithography technology, graphene oxide It is imprisoned in the rigid long chain of acrylic polymer; the present invention uses projection micro-stereolithography technology to manufacture three-dimensional porous graphene film, which can assemble two-dimensional graphene nanosheets in a large range, and retain its original structure while forming a three-dimensional structure. Some physical and chemical properties, with a large specific surface area, three-dimensional conductive path and porous structure, can provide more active sites for the immobilization of immune proteins, facilitate the capture and immobilization of biological particles, and can significantly detect tumor biomarkers.

Description

technical field [0001] The invention relates to the technical field of microfluidic chips, in particular to a method for preparing a three-dimensional porous graphene film and a microfluidic chip. Background technique [0002] Microfluidic Chip (Microfluidic Chip) refers to a micro-dose fluid (10 -9 -10 -18 L) Excellent technique for performing various manipulation experiments. [0003] Electrochemical detection is a commonly used analytical detection method. Its principle is to use electrodes as sensors to directly convert the chemical signals of the components to be measured in the solution into electrical signals. [0004] An electrochemical microfluidic detection chip can be obtained by integrating the electrodes for electrochemical detection on the microfluidic chip. In the field of bioanalysis, people use chips to capture tumor cell-related protein markers. The detection requires less sample volume and low detection limit, which highlights good application value in ...

AI Technical Summary

Problems solved by technology

[0007] Aiming at the technical problem that the existing three-dimensional porous graphene layer is difficult to construct a controllable three-dimensional structure, and the three-dimensional structure is too simple and simple, the present invention provides a preparation method of a three-dimensional porous graphene film and its microfluidic chip, which can Scope of assembly of two-dimensional graphene nanosheets, which retains its original physical and chemical properties while forming a three-dimensional structure, with large specific surface area, three-dimensional conductive paths and porous structure

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