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Fiber having cell affinity and fiber product produced using same

A kind of affinity and fiber technology, applied in the field of fiber products, can solve the problems of insufficient biocompatibility, artificial ligaments cannot be implanted for a long time, and high cost, so as to improve the compatibility of cells and tissues, and improve the quality of cells and/or materials Adhesiveness, the effect of increasing the surface area of ​​fibers

Pending Publication Date: 2020-12-04
TAIWAN TEXTILE RESEARCH INSTITUTE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Artificial ligaments cannot be implanted for a long time, and are prone to wear and loosening
In addition, existing products also have the disadvantages of insufficient biocompatibility, such as poor hydrophilicity of the PET surface, which is unfavorable for cell attachment, etc.
On the other hand, product technology needs to be imported, which leads to high cost

Method used

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Examples

Experimental program
Comparison scheme
Effect test

experiment example

[0023] In order to prove that the fiber with cell affinity proposed by the present invention and the fiber products made by using it can increase the surface area of ​​the fiber, improve the adhesion of cells and / or materials and improve the compatibility of cells and tissues, the following experiment is specially done example.

[0024] It must be noted that since the preparation method of the cell-affinity fiber has been described in detail above, the description of the preparation details for the preparation of the cell-affinity fiber will be omitted for the sake of convenience.

[0025] fiber preparation

[0026] The polyethylene terephthalate fibers with circular cross-section, cross-section and straight cross-section were treated with collagen surface respectively, and the reaction concentration and collagen content of collagen are shown in Table 1 below.

[0027] Table 1

[0028] Collagen reaction concentration (wt%) Collagen content (wt%) Round secti...

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Abstract

Provided are: a fiber having cell affinity, which is a polyethylene terephthalate fiber surface-treated with collagen, and which has a profiled cross-section; and a fiber product produced using the fiber.

Description

technical field [0001] The invention relates to a fiber and a fiber product made by using it, in particular to a fiber with cell affinity and a fiber product made by using it. Background technique [0002] For the rupture and reconstruction of tendon or ligament, the current clinical operation is mainly based on autologous tendon or ligament with soft tissue fixation device, and the implant of tendon or ligament needs to be strengthened to overcome clinical problems. For example, taking autologous tissue for repair has a certain impact on the patient's transplant site. Artificial ligaments cannot be implanted for a long time, and are prone to wear and loosening. In addition, the existing products also have the disadvantages of insufficient biocompatibility, such as poor hydrophilicity of the PET surface, which is not conducive to cell attachment. On the other hand, product technology needs to be imported, which leads to high costs. [0003] Based on the above, it is an im...

Claims

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Application Information

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IPC IPC(8): D06M15/15A61L27/24A61L27/18D06M101/32
CPCD06M15/15A61L27/24A61L27/18A61L2430/10D06M2101/32C08L67/02
Inventor 陈奕村李瑞生
Owner TAIWAN TEXTILE RESEARCH INSTITUTE
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