Pharmaceutical composition and preparation method and application thereof

A composition and pharmaceutical preparation technology, applied in the field of pharmaceutical compositions and their preparation, can solve the problems of insignificant anti-inflammatory effect and the like, and achieve the effects of improving the anti-inflammatory treatment effect, shortening the fermentation process, and controlling the fermentation process

Inactive Publication Date: 2021-01-05
TIBET QIZHENG TIBETAN MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Therefore, the technical problem to be solved by the present invention is to overcome the shortcomings of the anti-inflammatory pharmaceutical compositio

Method used

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  • Pharmaceutical composition and preparation method and application thereof
  • Pharmaceutical composition and preparation method and application thereof
  • Pharmaceutical composition and preparation method and application thereof

Examples

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Effect test

Embodiment 1

[0069] This embodiment provides a kind of pharmaceutical composition and preparation method thereof, and the raw material of this pharmaceutical composition comprises 2.5kg imperina root, 2.5kg branch subchrysanthemum, 2.5kg juniper, 2.5kg strong fragrant rhododendron and 2.5kg water cypress branch ;

[0070] The preparation method of the above-mentioned pharmaceutical composition comprises,

[0071] Each raw material was pulverized into a fine powder with a particle diameter of 150 μm to obtain a powder.

Embodiment 2

[0073] This embodiment provides a pharmaceutical composition and a preparation method thereof. The raw materials of the pharmaceutical composition include 2.5kg of Imperata imperinae, 2.5kg of shrub chrysanthemum, 2.5kg of juniper, 2.5kg of rhododendron and 2.5kg of water cypress branch;

[0074] The preparation method of the above-mentioned pharmaceutical composition comprises,

[0075] (1) The preparation method of fermented bacterium liquid, comprises the step of bacterial classification activation and expanded cultivation (expanded cultivation), specifically as follows:

[0076] Strain activation: Select Rhizopus koji (one each of Rhizopus oryzae AS3.866 and Rhizopus oryzae AS3.851 freeze-dried powder), dissolve in sterile water, inoculate in 4 slant mediums, culture at 33°C for 48 hours, freeze Preservation, this step is carried out during the first production or when the strain is replaced; another piece of Rhizopus oryzae AS3.851 freeze-dried powder is selected, dissolv...

Embodiment 3

[0083] This embodiment provides a pharmaceutical composition and a preparation method thereof. The raw materials of the pharmaceutical composition include 2.5kg Imperata rhizome, 2.5kg branched Asia Chrysanthemum, 2.5kg Juniper, 2.5kg Lixiang Rhododendron, 2.5kg Shuiba branch And 0.4375kg alkali flower;

[0084] The preparation method of the above-mentioned pharmaceutical composition comprises the following steps,

[0085] Mix the rhizome of Imperata praecox, chrysanthemum chrysanthemum, juniper, Rhododendron japonica and water cypress branch, add 10 times the amount of water and Alkaline flower to extract twice, each extraction time is 1h, after filtering, combine and collect the filtrate, concentrate under reduced pressure, A concentrate with a density of 1.13 g / mL was obtained, which was spray-dried and fluidized-bed granulated to obtain granules.

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Abstract

The invention belongs to the technical field of medicine preparation and particularly relates to a pharmaceutical composition as well as a preparation method and application thereof. The pharmaceutical composition is prepared from lalang grass rhizome, chrysanthemum coronarium and/or chrysanthemum shrub, juniperus formosana, rhododendron anthopogonoide and myricaria germanica. The pharmaceutical composition has a relatively good anti-inflammatory effect. The pharmaceutical composition is prepared by compounding the lalang grass rhizome, the juniperus formosana, the chrysanthemum coronarium and/or the chrysanthemum shrub, the rhododendron anthopogonoide and the myricaria germanica; and when the pharmaceutical composition is applied to a patient, the tolerance and the compliance are improvedand the healing effect is obviously improved.

Description

technical field [0001] The invention belongs to the technical field of medicine preparation, and in particular relates to a medicine composition and its preparation method and application. Background technique [0002] One of the unique external treatment methods of Tibetan medicine in the bathroom of Tibetan medicine. It is created on the basis of hot spring bath therapy and based on the basic theory of traditional Tibetan medicine. It has wide indications, strong safety, and good curative effect. It is widely used in Tibetan areas. use. [0003] The rhizome of Imperata cylindrica (scientific name: Imperata cylindrica Beauv.var.major (Nees) C.E.Hubb.) is the dry rhizome of grass plant Imperata cylindrica Beauv.var.major(Nees) C.E.Hubb. Small handle; rhododendron is Rhododendron anthopogonoides Maxim., Rhododendron cephalanthum Franch. and Rhododendron primulaeflarum Bur.et Franch. Dried flowers and leaves, born in forest margins or forest gaps at an altitude of 2500-4200 ...

Claims

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Application Information

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IPC IPC(8): A61K36/899A61P29/00A61P19/02A61K33/00
CPCA61K33/00A61K36/14A61K36/185A61K36/28A61K36/45A61K36/899A61K2236/19A61P19/02A61P29/00A61K2300/00
Inventor 刘渊宏陈丽娟张樱山
Owner TIBET QIZHENG TIBETAN MEDICINE
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