Application of VSM in preparation of medicine for treating rhabdomyosarcoma

A technology for rhabdomyosarcoma and drugs, applied in the field of medicine, can solve problems such as failure of treatment methods

Active Publication Date: 2021-02-12
SHANDONG ANALYSIS & TEST CENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in cases of advanced RMA and tumor recurrence, established treatments often fail, necessitating new therapeutic strategies

Method used

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  • Application of VSM in preparation of medicine for treating rhabdomyosarcoma
  • Application of VSM in preparation of medicine for treating rhabdomyosarcoma
  • Application of VSM in preparation of medicine for treating rhabdomyosarcoma

Examples

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Embodiment Construction

[0036] Below in conjunction with specific embodiment, further illustrate the present invention. It should be understood that these examples are only used to illustrate the present invention and are not intended to limit the scope of the present invention. For the experimental methods without specific conditions indicated in the following examples, usually follow the conventional conditions or the conditions suggested by the manufacturer.

[0037] Unless otherwise defined, all professional and scientific terms used herein have the same meanings as commonly understood by those skilled in the art. The reagents or raw materials used in the present invention can be purchased through conventional channels. Unless otherwise specified, the reagents or raw materials used in the present invention are used in accordance with conventional methods in the art or according to product instructions. In addition, any methods and materials similar or equivalent to those described can be applied...

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Abstract

The invention provides an application of VSM in preparation of a medicine for treating rhabdomyosarcoma. The VSM can be used for actin cytoskeleton, reducing motility, invasiveness, colony formation,growth and proliferation level of tumor cells and further causing metabolic closure, has effective actin silk stability and low side effect, and can be used for treating infantile alveolar rhabdomyosarcoma.

Description

technical field [0001] The invention relates to the field of medicine, in particular to the application of VSM in the preparation of medicines for treating rhabdomyosarcoma. Background technique [0002] The information disclosed in this background section is only intended to increase the understanding of the general background of the present invention, and is not necessarily taken as an acknowledgment or any form of suggestion that the information constitutes the prior art already known to those skilled in the art. [0003] Rhabdomyosarcoma (RMS) is the most common childhood soft tissue tumor, accounting for about 6-8% of all childhood malignancies. The RMS tumor type arises from skeletal muscle cells and results from a failure of the myogenic differentiation program. RMS can be histologically divided into several subtypes. The two most common subtypes are embryonic (RME; 70%) and alveolar (RMA; 20%). The most challenging issue in treating RMS patients is the prevention ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/24A61P35/00A61P35/04
CPCA61K36/24A61P35/00A61P35/04
Inventor 王岱杰娜嘉·恩格尔施树云崔莉伊夫蒂哈尔·阿里希达悦·侯赛因巴拉·西约林云良
Owner SHANDONG ANALYSIS & TEST CENT
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