A traditional Chinese medicine composition for treating leukoencephalopathy and its application

Abstract

The invention discloses a traditional Chinese medicine composition for treating leukoencephalopathy and its application. The traditional Chinese medicine composition is made of raw materials in the following weight proportions: 8-30 parts of distiller's root, 10-50 parts of kudzu root, and 10-50 parts of poria cocos 30 parts, 6-15 parts of Polygala and 0.2-1.0 parts of artificial bezoar. The invention also discloses the application of the above-mentioned traditional Chinese medicine composition in the preparation of medicine for treating leukoencephalopathy. The traditional Chinese medicine composition of the present invention is aimed at invigorating the kidney and strengthening the spleen, resolving phlegm and promoting blood circulation, detoxifying and dredging collaterals, treating ischemic leukoencephalopathy, and effectively improving cognitive dysfunction, depression, dizziness and insomnia caused by ischemic leukoencephalopathy. .

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine. More specifically, it relates to a traditional Chinese medicine composition for treating leukoencephalopathy and its application. Background technique [0002] Ischemic leukoencephalopathy is caused by chronic cerebral insufficiency leading to damage to the myelin sheath of central nerve cells in the white matter of the brain. Its clinical manifestations are mainly emotional and cognitive disorders, such as anxiety, depression, cognitive decline and even dementia. It is now generally believed that white matter lesions (WML), leukoaraiosis (LA), mild cognitive impairment (MCI), vascular dementia (VD), vascular Depression (vascular depression, VD) and cerebral small vessel disease (cerebral small vessel disease, SVD) all belong to the category of this disease. The disease mostly occurs in middle-aged and elderly people, and the incidence rate increases with age. Studies have ...

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Problems solved by technology

[0003] At present, Western medicine is not completely clear about the pathogenesis of this disease, and there is no clear treatment method, mainly from changing living habits, controlling the risk factors of cerebral small vessel disease, and applying cholinesterase inhibitors, serotonin reuptake inhibitors, etc. Drugs and other drugs to improve mental and emotional disorders, etc.

TCM scholars have reported a lot of studies on the etiology and pathogenesis of the disease, treatment principles, and TCM treatment. Most TCM scholars advocate whether TCM can improve the common clinical symptoms caused by ischemic leukoencephalopathy, such as cognitive dysfunction, Depression, etc., are the research content. Various related scoring scales are used as the evaluation criteria for symptom improvement, or whether various indicators related to blood rheology can be reduced as the standard for the effectiveness of treatment. There are few research reports on whether treatment methods can improve the microscopic pathological structure of leukoencephalopathy

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