Traditional Chinese medicine composition for treating leukoencephalopathy and application thereof

Abstract

The invention discloses a traditional Chinese medicine composition for treating leukoencephalopathy and application thereof. The traditional Chinese medicine composition is prepared from the followingraw material medicines in parts by weight: 8-30 parts of wine-processed rhizoma polygonati, 10-50 parts of radix puerariae, 10-30 parts of poria cocos, 6-15 parts of processed radix polygalae and 0.2-1.0 part of calculus bovis factitius. The invention further discloses the application of the traditional Chinese medicine composition in preparation of medicines for treating leukoencephalopathy. Thetraditional Chinese medicine composition aims to tonify kidney and spleen, reduce phlegm and activate blood circulation, detoxify and dredge collaterals, treat ischemic leukoencephalopathy and effectively treat cognitive decline, depression, dizziness, insomnia and the like caused by ischemic leukoencephalopathy.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine. More specifically, it relates to a traditional Chinese medicine composition for treating leukoencephalopathy and its application. Background technique [0002] Ischemic leukoencephalopathy is caused by chronic cerebral insufficiency leading to damage to the myelin sheath of central nerve cells in the white matter of the brain. Its clinical manifestations are mainly emotional and cognitive disorders, such as anxiety, depression, cognitive decline and even dementia. It is now generally believed that white matter lesions (WML), leukoaraiosis (LA), mild cognitive impairment (MCI), vascular dementia (VD), vascular Depression (vascular depression, VD) and cerebral small vessel disease (cerebral small vessel disease, SVD) all belong to the category of this disease. The disease mostly occurs in middle-aged and elderly people, and the incidence rate increases with age. Studies have ...

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Problems solved by technology

[0003] At present, Western medicine is not completely clear about the pathogenesis of this disease, and there is no clear treatment method, mainly from changing living habits, controlling the risk factors of cerebral small vessel disease, and applying cholinesterase inhibitors, serotonin reuptake inhibitors, etc. Drugs and other drugs to improve mental and emotional disorders, etc.

TCM scholars have reported a lot of studies on the etiology and pathogenesis of the disease, treatment principles, and TCM treatment. Most TCM scholars advocate whether TCM can improve the common clinical symptoms caused by ischemic leukoencephalopathy, such as cognitive dysfunction, Depression, etc., are the research content. Various related scoring scales are used as the evaluation criteria for symptom improvement, or whether various indicators related to blood rheology can be reduced as the standard for the effectiveness of treatment. There are few research reports on whether treatment methods can improve the microscopic pathological structure of leukoencephalopathy

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