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A device and method for detecting social interaction decision-making behavior of mice

A social interaction and testing device technology, applied in the field of animal behavior, can solve problems such as the inability to study the brain circuit mechanism of social incentives, and achieve the effect of a clear behavior testing process

Active Publication Date: 2022-04-15
FOURTH MILITARY MEDICAL UNIVERSITY
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, there is no effective social motivation behavior paradigm, so it is impossible to study the brain circuit mechanism of social motivation

Method used

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  • A device and method for detecting social interaction decision-making behavior of mice
  • A device and method for detecting social interaction decision-making behavior of mice

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Experimental program
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Embodiment Construction

[0034] The present invention will be described in detail below in conjunction with the accompanying drawings.

[0035] refer to figure 1 , a device for detecting social interaction decision-making behavior of mice, comprising a translucent experimental box 1 and a signal input and output control module on the top of the experimental box 1, the signal input and output control module includes a controller, a memory, a lighting system, Infrared camera system and sound stimulation system; the controller and the memory are connected through the I / O interface, the switch control signal input end of the lighting system, sound stimulation system and reward delivery device is connected to the output end of the controller, and the signal input and output control module is set The power interface is used to connect the external power supply. The experimental box 1 is provided with ventilation holes. At least two fences 2 are arranged in the experimental box 1. Audio data for stimulating ...

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Abstract

The invention discloses a device and method for detecting social interaction decision-making behavior of mice. The device includes a translucent experimental box and a signal input and output control module on the top of the experimental box. The signal input and output control module includes a controller, a memory, The lighting system, the infrared camera system and the sound stimulation system; the controller and the memory are connected through the I / O interface, the switch control signal input terminals of the lighting system, the sound stimulation system and the reward delivery device are connected to the output terminals of the controller, and the signal input The output control module is set to connect to the power interface of the external power supply, vent holes are set on the experimental box, at least two fences are set in the experimental box, and the audio data in the memory; it can be used to study the latent period of each social decision-making of mice and the correct decision-making rate; it can automatically record the fine behavior, movement trajectory, speed and time ratio of mice in the experimental device, and provide data for evaluating the normal state of mice.

Description

technical field [0001] The invention belongs to the technical field of animal behavior, and in particular relates to a device and method for detecting the social communication decision-making behavior of mice. Background technique [0002] Social communication generally refers to the social activities in which individuals communicate with each other under certain conditions and carry out material and spiritual exchanges to promote the growth of individuals. Disorders in social interaction are more common in mental disorders such as autism, anxiety and depression. Taking autism as an example, autism, also known as autism, is a common pervasive neurodevelopmental disorder, and the analysis of its behavior records can further clarify the structural and functional abnormalities of the nervous system that lead to its social impairment. Based on the natural tendency of mice to explore new things, current behavioral studies on social interaction disorders in mice mostly use the re...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A01K29/00
CPCA01K29/005
Inventor 毛宏晖郭保霖王文挺刘海鹰武胜昔祁楚楚黄鑫莫辉明
Owner FOURTH MILITARY MEDICAL UNIVERSITY
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