Anesthesia dressing and preparation method thereof

A technology of drug and slow-release microspheres, which is applied in the field of medical supplies, can solve the problems of troublesome cleaning, concentrated onset of anesthesia drugs, and long onset of anesthesia, and achieve the goals of prolonging the duration, being simple and convenient to use, and shortening the onset of effect Effect

Active Publication Date: 2021-05-14
QIANFOSHAN HOSPITAL OF SHANDONG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Anesthesia ointment is easy to contaminate clothes, is easy to be wiped off and affects the anesthesia effect, and it is troublesome to clean up, and there are problems such as long anesthesia onset time, concentrated anesthesia drug onset, and shor

Method used

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  • Anesthesia dressing and preparation method thereof
  • Anesthesia dressing and preparation method thereof

Examples

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Effect test

preparation example Construction

[0093] The preparation method of anesthesia dressing provided by the invention comprises:

[0094] Mixing the anesthetic drug, the anesthetic drug slow-release microspheres and the gel matrix material uniformly to obtain an anesthetic mixture, and preparing the anesthetic mixture into a flake-like anesthetic layer;

[0095] Lay an isolation film on one side of the anesthesia layer, then spread a self-heating material on the side of the isolation film away from the anesthesia layer, and then lay a breathable film on the self-heating material to make an anesthesia dressing; spread the self-heating material Both the process and the laying of the breathable membrane are carried out in an anaerobic environment, and the anesthetic dressing is immediately sealed and packaged in an anaerobic environment after the preparation is completed.

[0096] Wherein, the thickness of the anesthetic layer may be 2-5mm. The thickness of the self-heating material may be 1-5 mm.

[0097] The weigh...

Embodiment 1

[0139] an anesthetic dressing, such as figure 1 As shown, it includes an anesthesia layer 1 and a heating layer, wherein the anesthesia layer 1 is a gel containing anesthesia drugs and anesthesia drug slow-release microspheres, and the heating layer includes an isolation film 2, a self-heating material 3 and a gas-permeable film 4 in sequence, and the isolation The membrane 2 is adjacent to the anesthesia layer 1, the thickness of the anesthesia layer 1 is 3 mm, and the thickness of the self-heating material 3 is 2 mm;

[0140] Preparation methods for anesthesia dressings include:

[0141] S1. Preparation of anesthesia sustained-release microspheres: Dissolve 200g of lidocaine in 1L of ethanol to form an inner oil phase, dissolve 300g of polylactic acid in 2L of ethyl acetate to form an outer oil phase, and inject the inner oil phase into the outer oil phase Mix evenly to form a mixed oil phase; add 200g polyvinyl alcohol into 20L water and stir evenly to form an outer water ...

Embodiment 2

[0147] an anesthetic dressing, such as figure 2 As shown, it includes an anesthesia layer 1 and a heating layer, wherein the anesthesia layer 1 is a gel containing anesthesia drugs and anesthesia drug slow-release microspheres, and the heating layer includes an isolation film 2, a self-heating material 3 and a gas-permeable film 4 in sequence, and the isolation An adhesive layer 5 is arranged between the membrane 2 and the anesthesia layer 1, the thickness of the anesthesia layer 1 is 2 mm, and the thickness of the self-heating material 3 is 3 mm;

[0148] Preparation methods for anesthesia dressings include:

[0149] S1. Preparation of anesthesia drug slow-release microspheres: same as Example 1;

[0150] S2. Dissolve 10g glycerin in 30g purified water, then slowly add 8g sodium polyacrylate, stir until fully dissolved, add 2g guar gum and 1g chitosan quaternary ammonium salt, stir until fully dissolved, then add 10g lidocaine and 28g Anesthesia drug sustained-release micr...

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Abstract

The invention belongs to the field of medical supplies, and provides an anesthesia dressing and a preparation method thereof. The anesthetic dressing comprises an anesthetic layer and a heating layer, the anesthetic layer is gel containing anesthetic and anesthetic sustained-release microspheres, and the heating layer sequentially comprises an isolating membrane adjacent to the anesthetic layer, a self-heating material and a breathable membrane. The anesthesia dressing provided by the invention is simple and convenient to use and convenient to apply, and does not need to be cleaned after being used; the anesthesia medicine and the anesthesia medicine slow-release micro-capsule are used in cooperation to prolong the duration of the anesthesia effect, the onset time of the anesthesia medicine is shortened in a heating mode, and therefore the anesthesia dressing has the advantages of being fast in onset of the anesthesia effect and long in duration of the anesthesia effect, can be widely applied to various surgeries needing surface anesthesia, and is suitable for various surgeries needing surface anesthesia. And the anesthesia dressing can be conveniently applied to postoperative analgesia and treatment of various intractable pains.

Description

technical field [0001] The invention belongs to the field of medical supplies, and in particular relates to an anesthesia dressing and a preparation method thereof. Background technique [0002] Anesthesia can relieve patients' pain during surgery, so it is widely used in almost all major and minor operations. Anesthesia can be divided into general anesthesia and local anesthesia. Local anesthesia refers to the ability to temporarily, completely and reversibly block nerve conduction within the limited range of the human body, that is, to make a certain part of the human body lose sensation without losing consciousness. to facilitate surgery. The traditional local anesthesia method generally involves injection of local anesthetics, which is cumbersome to operate, and patients are prone to fear and cannot cooperate. In recent years, topical anesthesia has been used more and more clinically. Surface anesthesia refers to the method of directly applying anesthetics on the pati...

Claims

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Application Information

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IPC IPC(8): A61K9/70A61K31/167A61P23/00A61P29/00
CPCA61K9/7007A61K31/167A61K47/36A61P23/00A61P29/00
Inventor 谷长平张亚强刘孟洁
Owner QIANFOSHAN HOSPITAL OF SHANDONG
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