19 results about "Analgesia postoperative" patented technology

The invention discloses an intelligent control method for an analgesia pump based on deep learning. The intelligent control method comprises the following steps: S1, acquiring multi-modal original signals of a postoperative patient and synchronously normalizing the multi-modal original signals; s2, removing artifacts and noise in the synchronous data, and performing interpolation compensation on missing data; s3, carrying out modal reliability weight distribution on the sensing sequence based on a Hemma optimization algorithm; s4, inputting the node set into a PainNet relation statistical network to generate a dynamic graph topological structure; s5, predicting the pain score of the patient in the future, and generating a low-dose high-frequency micro-pulse administration instruction; s6, according to the circadian rhythm of the patient, dynamically adjusting the edge weight and the administration interval of the PainNet network; and S7, when the pain score fluctuation exceeds the limit, triggering an emergency mode, quickly converging to the most conservative parameter combination, and outputting a safety locking instruction. According to the invention, the control accuracy and safety of postoperative analgesia are improved.

The invention provides an interpretable postoperative analgesia formula intelligent recommendation method based on a decision tree, and the method comprises the following steps: S1, according to hospital postoperative analgesia case data, determining patient characteristics and analgesia drugs, the patient characteristics comprising continuous variables and discrete variables, the analgesia drugs being the continuous variables, and preprocessing the case data; s2, performing feature construction and feature selection on the patient features, and taking the selected patient features and analgesic drugs as data sources; s3, taking the preprocessed medical record data as a training sample of a decision tree algorithm, and performing analgesia formula model learning to obtain a learned model; and S4, inputting test case data into the learned model for prediction to obtain a final analgesic formula. Through application of the artificial intelligence technology in the field of postoperative analgesia, medical and industrial crossing is promoted, intelligent recommendation of analgesia formula decisions is achieved, and therefore the workload of doctors in the process of formulating analgesia formulas is greatly reduced.

The invention relates to the technical field of automatic drug delivery control, in particular to a drug delivery control method and system for a surgical postoperative analgesia pump, and the method comprises the following steps: obtaining a respiratory rate and a pressing behavior sequence of a patient, recognizing a fluctuation trend and request growth, judging a synchronous response time period, and adjusting an infusion rhythm and dosage. Pressure curve characteristics are analyzed to recognize abnormal operation, emergency infusion is executed in combination with signal linkage, and a dynamic drug administration control instruction is generated. According to the method, the severe fluctuation identification is generated by obtaining the continuous breathing frequency change trend of the patient and combining with breathing extreme value judgment, the linkage time period mark is formed by matching with sequential change trend analysis of the request behavior of the patient, and the basic infusion frequency and dosage are adjusted in real time to meet the actual analgesia requirement; an intelligent recognition and quick response mechanism under the dominant physiological state is achieved, the adaptability, safety and timeliness of the analgesia process are enhanced, and the problems of control lag and judgment blind areas in a fixed parameter mode are effectively relieved.

The present application belongs to the field of pharmaceutical preparations, and relates to a meloxicam composition, preparation and preparation method and application. One aspect of the present application provides a meloxicam composition, which comprises meloxicam and a latent solvent, wherein the latent solvent is a mixed solvent comprising water and an organic solvent. Another aspect of the present application provides another composition, which comprises meloxicam, a solvent and a pH regulator, wherein the pH regulator at least comprises citric acid. The pharmaceutical composition of the present application can significantly improve the solubility of meloxicam in liquid preparation, and has excellent stability. The meloxicam composition provided by the present application can even be directly used for intravenous injection administration, and quickly reaches an effective therapeutic concentration for postoperative analgesia. In addition, the preparation process of the composition is simple, and can be completed by stirring and dispersing at room temperature for a short time, so that the scale-up production is easy to realize.

The application provides an intelligent postoperative analgesia method and device based on voice recognition control, and relates to the technical field of postoperative analgesia. The method comprises the following steps: initializing the analgesia infusion level of an analgesia pump as an intermediate level, wherein the analgesia pump is provided with multiple levels, and the levels are arranged in ascending order according to the analgesia infusion dose; the analgesia pump is activated by voice in response to the occurrence of discomfort symptoms of a patient, and the analgesia pump is controlled to inquire whether the patient has insufficient analgesia or excessive analgesia; if the patient feeds back insufficient analgesia, the analgesia pump is controlled to execute single-dose administration or to increase the analgesia infusion level; and if the patient feeds back excessive analgesia, the analgesia pump is controlled to suspend drug infusion or to reduce the analgesia infusion level. Through voice control and dynamic dose adjustment technology, convenient operation and individualized analgesia management are realized, the problems of insufficient analgesia or excessive analgesia caused by fixed dose setting in a traditional analgesia pump are avoided, the frequent intervention of medical staff is reduced, and the safety and effect of postoperative analgesia are improved.

The present invention provides a long-acting K-opioid receptor agonist. This long-acting K-opioid receptor agonist is used to alleviate moderate to severe itching in patients and for postoperative pain relief.

The utility model belongs to the technical field of analgesia pumps, and particularly relates to an anesthesia postoperative analgesia pump which comprises an analgesia pump body, a fixing plate is fixed to the top of the analgesia pump body, an installation assembly is movably connected to the outer side of the fixing plate in a sleeved mode, the installation assembly comprises an installation plate, a pin, a limiting frame and a connecting plate, the pin is arranged on one side wall of the installation plate, and the limiting frame is arranged on the other side wall of the installation plate. A limiting frame is fixed to the other side wall of the mounting plate, a connecting plate is arranged on the other side of the mounting plate, an inserting plate is fixed to one end of the connecting plate, the inserting plate is inserted into the inner side of the limiting frame, the other end of the connecting plate is connected to the outer side of the fixing plate in a sleeving mode, and a magnetic clamping groove is formed in one side wall of the connecting plate. A magnetic clamping plate is fixed to the side wall of the mounting plate and located on one side of the magnetic clamping groove. The portable analgesia pump improves the carrying stability, is convenient to carry, and avoids the situation that the stability is insufficient when a clamp structure is adopted conventionally.

This invention discloses a system for locating the trident sign for psoas major muscle block of the intertransverse ligament, belonging to the field of medical anesthesia technology. It solves the technical problems of traditional psoas major muscle block procedures, such as inaccurate localization, reliance on experience, lack of objective indicators for efficacy verification, and lack of closed-loop feedback. The system comprises four modules: patient preparation and positioning, ultrasound scanning and trident sign localization, puncture and block administration, and efficacy evaluation. It uses the "trident sign" of the lumbar transverse processes as the basic localization landmark and the intertransverse ligament as the key puncture landmark. It employs in-plane puncture, tactile feedback, and real-time ultrasound imaging for dual verification to achieve precise needle tip localization. This invention achieves precise localization, standardized puncture, objective efficacy, and a systematic process for psoas major muscle block, reducing reliance on physician experience, achieving a success rate of ≥95%, significantly reducing the incidence of complications, and demonstrating strong repeatability. It is suitable for regional anesthesia and postoperative analgesia in clinical lumbar spine surgeries.

The present invention relates to pharmaceutical formulations comprising 2-{[3-(5-chloro-2-{2-chloro-5-fluoro-4-[(1,3-thiazol-4-yl)sulfamoyl]phenoxy}phenyl)propyl]amino}acetamide, or a pharmaceutically acceptable salt thereof, for extended release, to methods for preparation thereof, and to uses thereof for treatment of pain or providing peri-operative anesthesia or post-operative analgesia.

This invention relates to the fields of biomedicine and nanomaterials technology, and provides a bilayer core-shell nanoparticle composite thermosensitive gel for postoperative analgesia, its preparation method, and its applications. The bilayer core-shell nanoparticles comprise: a core of PLGA nanoparticles loaded with magnesium, and a shell of a lipid bilayer loaded with bupivacaine. The composite thermosensitive gel is made by uniformly dispersing the bilayer core-shell nanoparticles in a thermosensitive gel material. By constructing a structure with a lipid shell loaded with bupivacaine and a PLGA core loaded with magnesium, and combining it with a thermosensitive gel, this invention achieves rapid release of bupivacaine for acute postoperative analgesia, and sustained slow release of magnesium ions for long-term anti-inflammatory and repairing effects. This perfectly meets the temporal requirements of postoperative pain management and has broad clinical application prospects.

The application provides a combination of flurbiprofen axetil and oxeladin fumarate for postoperative analgesia and immune protection of patients with bone tuberculosis. Specifically, the application provides use of flurbiprofen axetil and oxeladin fumarate for preparing an analgesic drug for patients with bone tuberculosis surgery. The application also provides a pharmaceutical composition comprising flurbiprofen axetil and oxeladin fumarate, an analgesic drug kit, a pharmaceutical use and an analgesic method for patients with bone tuberculosis surgery. In the application, the combination of flurbiprofen axetil and oxeladin fumarate produces a synergistic analgesic effect, effectively solves the problem of poor analgesic effect in some patients, reduces the single drug dose and adverse reactions, and is beneficial to immune regulation of patients with bone tuberculosis surgery and accelerates the recovery of patients. The application provides a safer and more effective analgesic method and analgesic drug for patients with bone tuberculosis surgery, and the analgesic method and analgesic drug have a protective effect on the immune function of patients.

The application belongs to the technical field of medical anesthetic apparatus, and provides a 6-hole reinforced epidural catheter and a preparation process thereof, wherein the 6-hole reinforced epidural catheter comprises a catheter main body, a reinforcing assembly, a medicine outlet assembly, an anti-injury tip, a scale mark and a connecting joint; the catheter main body is a hollow tubular structure and is made of hydrophilic modified medical polyurethane material; the catheter main body is sequentially divided into an insertion section, a transition section and a connecting section along an axial direction; the reinforcing assembly is embedded in the pipe wall of the catheter main body and penetrates through the whole length of the catheter main body; and the reinforcing assembly is a composite structure composed of double helical steel wires and a fiber reinforced layer; the application improves the catheter's resistance to folding and pulling and the uniformity of medicine outlet, reduces the risk of catheterization injury, is accurate and convenient to operate, and is suitable for industrialized production, and is suitable for epidural anesthesia and postoperative analgesia.

The present invention relates to pharmaceutical formulations comprising 2-{[3-(5-chloro-2-{2-chloro-5-fluoro-4-[(1,3-thiazol-4-yl)sulfamoyl]phenoxy}phenyl)propyl]amino}acetamide, or a pharmaceutically acceptable salt thereof, for extended release, to methods for preparation thereof, and to uses thereof for treatment of pain or providing peri-operative anesthesia or post-operative analgesia.

The invention relates to the technical field of medical instruments, in particular to an individualized anesthesia nursing device based on postoperative analgesia management, which comprises a medical terminal for a doctor or a nurse to log in and operate and a catheter communicated with an analgesia pump body, and the catheter is communicated with an automatic control mechanism for adjusting the flow in the catheter; the self-control mechanism comprises a shell, a button is in sliding fit with the center of the shell, a magnet block is fixedly connected to the bottom of the button, and coils are arranged around the magnet block; the guide pipe is located below the button, a plurality of abutting blocks used for sealing the guide pipe abut against the guide pipe, and an electromagnet electrically connected with the coil is arranged below the abutting blocks. The coil is electrically connected with a transmission module used for recording current data generated by the coil, and the medical terminal is used for drawing a frequency diagram of the current time period based on the current data and controlling the conveying flow of the analgesia pump body based on the frequency diagram. The system is supervised by medical staff, and medication standard management of self-control analgesia of a patient is achieved.

The present application provides a kind of compound phospholipid gel sustained-release preparation and its preparation method.The preparation mainly contains local anesthetics, non-steroidal anti-inflammatory drugs, phospholipids and water for injection.The preparation can be injected around the surgical incision or directly instilled or coated on the surgical incision site to achieve long-acting analgesic purpose, for postoperative analgesia.

The invention relates to an injectable etoricoxib injection true solution or injection etoricoxib for postoperative analgesia and a composition thereof. The composition comprises an active component etoricoxib, water for injection, an injectable acid, an injectable alkali and sulfobutyl beta-cyclodextrin sodium.

To improve the accuracy of puncture and the success rate of the procedure in ultrasound-guided erector spinae muscle block. [Solution] The spinal erector muscle surface block puncture needle guide device for postoperative pain relief comprises a base 1 having a housing space for an ultrasound probe and an acoustic perforation hole at the bottom; a needle path guide mechanism 4 including a guide tube 5 rotatably connected to the base 1; an angle adjustment mechanism 7 for adjusting and locking the angle of the guide tube 5 relative to the base 1; and a depth limiting mechanism 10 adjustablely provided in the lumen of the guide tube 5 to limit the maximum insertion depth of the puncture needle. Under ultrasound guidance, it provides stable needle path guidance and precise angle and depth control to the puncture needle, allowing the puncture needle to accurately reach the target gap between the deep surface and transverse process of the spinal erector muscle, improving puncture accuracy and operational success rate.

The invention provides a flurbiprofen axetil and oxiselidine fumarate combination scheme for postoperative analgesia and immune protection of bone tuberculosis patients. Specifically, the invention provides application of flurbiprofen axetil and oxiselidine fumarate, and the flurbiprofen axetil and oxiselidine fumarate are used for preparing analgesic drugs for bone tuberculosis operation patients. The invention also provides a pharmaceutical composition containing flurbiprofen axetil and oxiselidine fumarate, an analgesic drug kit, pharmaceutical application and an analgesic method for bone tuberculosis surgical patients. According to the invention, the flurbiprofen axetil and the oxiselidine fumarate are combined for use to generate a synergistic analgesic effect, so that the problem of poor analgesic effect of part of patients can be effectively solved, and the combined use reduces the single dosage and adverse reaction, is beneficial to immunoregulation of bone tuberculosis surgical patients and accelerates the rehabilitation of the patients. The analgesic method and the analgesic drug which are safer and more effective and have a protection effect on the immune function of a patient are provided for the patient with the bone tuberculosis operation.

The invention relates to the field of medical instruments, and discloses an anorectal clinical postoperative analgesia and hemostasis device which comprises a working box installed at the top of a base, a sponge mat is installed at the top of the working box, one end of the working box is rotationally connected with a rocker, and one end of the rocker is fixedly connected with a worm. The inner wall of the working box is rotatably connected with a plurality of worm wheels, the worm is in meshed connection with the worm wheels, the inner wall of one worm wheel is in threaded connection with a positioning column, the top of the positioning column is fixedly connected with a medicine feeding pipe, a liquid medicine box is arranged in the working box, and a liquid feeding pipe is installed at one end of the liquid medicine box; after pressurization of the pressurization assembly, the liquid feeding pipe is communicated with a plurality of liquid feeding grooves formed in the inner wall of the medicine feeding pipe, and an analgesia assembly is arranged at one end of the working box. Through cooperative use of a pressure box, a piston and other components, a patient can conduct postoperative medicine applying, analgesia and hemostasis by himself / herself, convenience is improved, and meanwhile privacy of the patient in the process of using the device is guaranteed.