A kind of anesthesia dressing and preparation method thereof
A technology of drugs and slow-release microspheres, applied in the field of medical supplies, can solve the problems of troublesome cleaning, centralized onset of anesthesia drugs, long onset time of anesthesia, etc. Effect
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[0093] The preparation method of anesthesia dressing provided by the invention comprises:
[0094] Mixing the anesthetic drug, the anesthetic drug slow-release microspheres and the gel matrix material uniformly to obtain an anesthetic mixture, and preparing the anesthetic mixture into a flake-like anesthetic layer;
[0095] Lay an isolation film on one side of the anesthesia layer, then spread a self-heating material on the side of the isolation film away from the anesthesia layer, and then lay a breathable film on the self-heating material to make an anesthesia dressing; spread the self-heating material Both the process and the laying of the breathable membrane are carried out in an anaerobic environment, and the anesthetic dressing is immediately sealed and packaged in an anaerobic environment after the preparation is completed.
[0096] Wherein, the thickness of the anesthetic layer may be 2-5mm. The thickness of the self-heating material may be 1-5 mm.
[0097] The weigh...
Embodiment 1
[0139] an anesthetic dressing, such as figure 1 As shown, it includes an anesthesia layer 1 and a heating layer, wherein the anesthesia layer 1 is a gel containing anesthesia drugs and anesthesia drug slow-release microspheres, and the heating layer includes an isolation film 2, a self-heating material 3 and a gas-permeable film 4 in sequence, and the isolation The membrane 2 is adjacent to the anesthesia layer 1, the thickness of the anesthesia layer 1 is 3 mm, and the thickness of the self-heating material 3 is 2 mm;
[0140] Preparation methods for anesthesia dressings include:
[0141] S1. Preparation of anesthesia sustained-release microspheres: Dissolve 200g of lidocaine in 1L of ethanol to form an inner oil phase, dissolve 300g of polylactic acid in 2L of ethyl acetate to form an outer oil phase, and inject the inner oil phase into the outer oil phase Mix evenly to form a mixed oil phase; add 200g polyvinyl alcohol into 20L water and stir evenly to form an outer water ...
Embodiment 2
[0147] an anesthetic dressing, such as figure 2 As shown, it includes an anesthesia layer 1 and a heating layer, wherein the anesthesia layer 1 is a gel containing anesthesia drugs and anesthesia drug slow-release microspheres, and the heating layer includes an isolation film 2, a self-heating material 3 and a gas-permeable film 4 in sequence, and the isolation An adhesive layer 5 is arranged between the membrane 2 and the anesthesia layer 1, the thickness of the anesthesia layer 1 is 2 mm, and the thickness of the self-heating material 3 is 3 mm;
[0148] Preparation methods for anesthesia dressings include:
[0149] S1. Preparation of anesthesia drug slow-release microspheres: same as Example 1;
[0150] S2. Dissolve 10g glycerin in 30g purified water, then slowly add 8g sodium polyacrylate, stir until fully dissolved, add 2g guar gum and 1g chitosan quaternary ammonium salt, stir until fully dissolved, then add 10g lidocaine and 28g Anesthesia drug sustained-release micr...
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