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Preparation method and application of acne-removing compound

A complex and anti-acne technology, which is applied in skin care preparations, medical preparations containing active ingredients, drug combinations, etc., can solve the problems of poor combination effect of compound liquid and incomplete effect

Inactive Publication Date: 2021-08-24
悠宜生物科技(江苏)有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In order to overcome the problem that the compound liquid in the prior art has poor binding effect and the effect cannot be fully exerted, the present invention proposes a preparation method of the acne-removing compound

Method used

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  • Preparation method and application of acne-removing compound
  • Preparation method and application of acne-removing compound
  • Preparation method and application of acne-removing compound

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] 1. Inoculate Saccharomyces cerevisiae cultured on a shaker in advance into yeast medium (YPD medium) for fermentation. The fermentation conditions are: pH range 3.5-5.0, fermentation temperature 25°C, shaker speed 80rpm, fermentation time 2d.

[0031] 2. Use a TDL-80-2B low-speed centrifuge to centrifuge the fermented broth at a speed of 7000 rpm / min, collect and separate the supernatant, and filter it through a 0.45 μm microporous membrane.

[0032] 3. The temperature used for the extraction of golden chamomile is 50°C, the ratio of solid to liquid is 1:15, and the ultrasonic-assisted extraction time is 70 minutes, then heated and boiled, concentrated to a density of 1.08g / ml (60°C), and filtered with double-layer gauze to obtain the filtrate , add butanediol to configure a solution with a ratio of liquid to butanediol of 1:1.

[0033]4. Centella asiatica flower / leaf / stem extract is made by crushing Centella asiatica, adding 60% ethanol as a solvent, and the ratio of s...

Embodiment 2

[0041] 1. Inoculate Saccharomyces cerevisiae cultured on a shaker in advance into yeast medium (YPD medium) for fermentation. The fermentation conditions are: pH range 3.5-4.5, fermentation temperature 25°C, shaker speed 80rpm, fermentation time 2d.

[0042] 2. Use a TDL-80-2B low-speed centrifuge to centrifuge the fermented broth at a speed of 7000 rpm / min, collect and separate the supernatant, and filter it through a 0.45 μm microporous membrane.

[0043] 3. The temperature used for the extraction of golden chamomile is 55°C, the ratio of solid to liquid is 1:18, and the ultrasonic-assisted extraction time is 75 minutes. After that, it is heated and boiled, concentrated to a density of 1.10g / ml, filtered with double-layer gauze to obtain the filtrate, and added dibutyl Alcohol is formulated as a 1:1 solution of liquid to butanediol.

[0044] 4. Centella asiatica flower / leaf / stem extract is made by crushing Centella asiatica, adding 65% ethanol as a solvent, and the ratio of ...

Embodiment 3

[0052] 1. Inoculate Saccharomyces cerevisiae cultured on a shaker in advance into yeast medium (YPD medium) for fermentation. The fermentation conditions are: pH range 3.5-4.5, fermentation temperature 25°C, shaker speed 80rpm, fermentation time 2d.

[0053] 2. Use a TDL-80-2B low-speed centrifuge to centrifuge the fermented broth at a speed of 7000 rpm / min, collect and separate the supernatant, and filter it through a 0.45 μm microporous membrane.

[0054] 3. The temperature used for the extraction of golden chamomile is 60°C, the ratio of solid to liquid is 1:20, and the ultrasonic-assisted extraction time is 75 minutes. After that, it is heated and boiled, concentrated to a density of 1.15g / ml, filtered with double-layer gauze to obtain the filtrate, and added dibutyl Alcohol is formulated as a 1:1 solution of liquid to butanediol.

[0055] 4. Centella asiatica flower / leaf / stem extract is made by pulverizing Centella asiatica, adding 70% ethanol as a solvent, and the ratio ...

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Abstract

The invention provides a preparation method and application of an acne removing compound, and belongs to the technical field of cosmetics. The method comprises: fermenting accharomycetes to obtain supernate of fermentation liquor; then adding 5-10% of a chrysanthellum indicum extract, 3-8% of a centella asiatica flower / leaf / stem extract, 5-10% of a rosemary extract, 0.5-1% of a salvia officinalis extract, 0.5-1% of a tea tree extract, 3-8% of a polygonum cuspidatum extract and 3-8% of a calendula officinalis extract in proportion, heating to 40-50 DEG C, and stirring for dissolving; and sterilizing and filtering to obtain the acne-removing compound. The method can effectively solve the problems that the combination effect of the compound liquid is poor and the effect cannot be completely exerted, and has better acne-removing and anti-oxidation effects. The acne-removing compound provided by the invention is formed by compounding various natural plant extracts, can effectively solve the problems that the combination effect of a compound liquid is poor and the effect cannot be completely exerted, has better acne-removing and anti-oxidation effects, and is safe and small in side effect.

Description

technical field [0001] The invention relates to the technical field of cosmetics, in particular to an acne-removing compound and its preparation method and application. Background technique [0002] In recent years, with the increase of life and work pressure, the development of electronic technology, irregular diet and sleep, and air pollution, people with acne are no longer limited to adolescence, and more and more people have acne. Acne, also known as "acne" or "acne", is a common chronic disease of the sebaceous glands. It occurs mostly in adolescence. Most of the causes of acne are endocrine disorders, excessive oil, and clogged pores. A small part is family heredity or skin disease infection, etc., which vary from person to person. [0003] Most acne-removing cosmetics on the market contain a large number of additives, which can easily affect the skin and even cause skin diseases. However, natural plant extracts are more and more favored by scholars and the market be...

Claims

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Application Information

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IPC IPC(8): A61K8/9789A61K8/9728A61Q19/00A61P29/00A61Q17/00A61P17/10
CPCA61K2800/5922A61K2800/85A61Q17/005A61Q19/00A61K8/9728A61K8/9789A61P17/10A61P29/00
Inventor 陈秀玉王绍梅秦涛郭星星詹柱刘晓磊丁冲冲郑海兵何沪宝
Owner 悠宜生物科技(江苏)有限公司
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