Composition for regulating ovarian reserve function and application thereof

A composition and drug technology, applied in the field of compositions regulating endocrine and metabolic disorders, to achieve the effects of increasing pregnancy rate, improving endocrine disorders, and improving the level of ovarian reserve function

Inactive Publication Date: 2021-10-22
王兴娟 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

How to improve the quality of follicles and ovarian reserve function, the current Western medicine has no good strategy

Method used

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  • Composition for regulating ovarian reserve function and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] The preparation of embodiment 1 ointment

[0038] Take 100-200 parts by weight of Codonopsis pilosula, 100-200 angelica, 150-300 donkey-hide gelatin, 50-150 antler glue, 100-200 tortoise shell glue and 10-50 tangerine peel, rinse with water, soak in a container for more than 2 hours, and then process traditional Chinese medicine. Process, boil to make ointment.

[0039] The mode of administration is: oral administration, 2 times a day, one teaspoon each time, clinical observation.

Embodiment 2

[0040] Example 2 Evaluation of curative effect

[0041] After treatment, the serum AMH level of the patients was significantly increased, and the serum LH and FSH levels were significantly lower than those before treatment (p<0.05), as shown in Table 1 below.

[0042] Table 1. Comparison of AMH, LH, FSH levels before and after treatment

[0043]

[0044]*p<0.05 compared to pre-treatment.

[0045] After therapeutic intervention, 15 of the 24 patients became pregnant, with an effective rate of 62.5%, among which 13 cases were naturally conceived with primary infertility, with an effective rate of 54.2%.

[0046] Among the 24 cases, 19 cases (79.2%) had premenstrual period and uterine bleeding. After treatment, 16 cases of 19 cases returned to normal menstruation, the effective rate was 84.2%, and 3 cases had unadjusted menstruation 15.8%.

[0047] Among the 24 cases, 6 had repeated in vitro fertilization (IVF) 3 times without success due to tubal disorder. After treatment, ...

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Abstract

The traditional Chinese medicine composition comprises the root of hairy asiabell , angelica sinensis, donkey-hide gelatin, deer-horn glue, tortoise-shell glue, dried tangerine or orange peel and the like. The composition provided by the invention can better improve female endocrine metabolism disorder, improve the ovarian reserve function level, adjust the menstrual cycle and remarkably increase the pregnancy rate of infertility patients.

Description

technical field [0001] The invention relates to a composition for regulating endocrine and metabolic disorders, in particular to a Chinese medicinal material composition for regulating women's ovarian reserve function, regulating menstrual cycle and treating infertility. Background technique [0002] Infertility includes both infertility and infertility. Couples of childbearing age have normal sexual life for more than 1 year, and they do not become pregnant without taking contraceptive measures. It is called infertility (infertility). The inability to obtain a surviving baby is called sterility. [0003] At present, the incidence of infertility among married couples in my country is about 10-15%, and 2 / 3 of the causes are women. The causes of female infertility include reproductive endocrine and metabolic dysfunction, reproductive organ lesions, immune chromosomes exception, there are other reasons etc. Among them, endocrine dysfunction factors account for the vast majorit...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61P15/00A61P15/08A61K35/36A61K35/32A61K35/586
CPCA61K36/344A61K36/232A61K35/36A61K35/32A61K35/586A61K36/752A61P15/00A61P15/08A61K2300/00
Inventor 王兴娟林捷
Owner 王兴娟
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