Semen cassiae compound collagen liposome and application thereof

A technology of cassia seed and collagen lipid, which is applied in the preparation field of cassia seed compound collagen liposome, can solve the problems of complicated preparation, production, many ingredients, protection, and preventive properties, and achieve the promotion of platelet aggregation and oral utilization High, bioavailability-enhancing effects

Active Publication Date: 2021-10-29
TIANJIN SHI JI KANG TAI BIOMEDICAL ENG CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the required raw materials are many, the preparation and production are cumbersome, and it needs to be used together with the equipment, and it is mainly for treatment, and the protection and prevention are unknown.

Method used

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  • Semen cassiae compound collagen liposome and application thereof
  • Semen cassiae compound collagen liposome and application thereof
  • Semen cassiae compound collagen liposome and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0072] Use the MEM medium containing double antibody and serum to prepare the cassia seed extract with a concentration of 10mg / mL, filter and sterilize, and dilute the cassia seed extract to 8mg / mL, 6mg / mL, 4mg with the MEM medium containing double antibody and serum / mL, 2mg / mL.

Embodiment 2

[0074] Dissolve compound lecithin with a small amount of absolute ethanol, and rotary steam under reduced pressure to form a film; prepare 10 mg / mL hydration solution containing cassia seed extract, filter, and preheat in water at 50°C; under the same conditions, add hydration solution Liquid hydration, after complete dissolution, sonicate until the solution is evenly clarified, filter and sterilize to obtain cassia seed liposome.

[0075] The compound lecithin described in the above-mentioned Example 2 includes egg yolk lecithin, anhydrous butter, and cholesterol in a mass ratio of 3:3:1.

Embodiment 3

[0077] Dissolve compound lecithin with a small amount of absolute ethanol, and rotary steam under reduced pressure to form a film; prepare 10mg / mL containing cassia seed extract, peppermint extract, dendrobium extract, water chestnut extract, red wolfberry extract, licorice extract and 5mg / mL The hydration solution of / mL collagen solution is filtered and preheated in water at 50°C; under the same conditions, add hydration solution for hydration, after complete dissolution, sonicate until the solution is uniform and clear, and then filter and sterilize to obtain the cassia seed compound collagen Liposomes.

[0078] The compound lecithin described in the third embodiment above includes egg yolk lecithin, anhydrous butter, and cholesterol in a mass ratio of 3:3:1.

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Abstract

The invention discloses a preparation method of semen cassiae compound collagen lipidosome and application thereof. The semen cassiae compound collagen liposome is prepared from the following raw materials in percentage by mass: 2.00 to 5.00 percent of compound lecithin, 12.00 to 25.00 percent of a semen cassiae extracting solution, 12.00 to 25.00 percent of a mint extracting solution, 12.00 to 25.00 percent of a herba dendrobii extracting solution, 12.00 to 25.00 percent of a water chestnut extracting solution, 12.00 to 25.00 percent of a red wolfberry extracting solution, 12.00 to 25.00 percent of a liquorice root extracting solution and 8.00 to 16.00 percent of a collagen solution. The semen cassiae compound collagen lipidosome has the effects of improving eyesight, preserving moisture, whitening, resisting wrinkles and being high in permeability, is mild and fresh in texture, can effectively relieve eyestrain and has the most obvious eyesight improving effect on eyes.

Description

technical field [0001] The invention relates to the technical field of liposome and application thereof, in particular to a preparation method and application thereof based on cassia seed compound collagen liposome. Background technique [0002] The skin around the eyes is weak and vulnerable to external environmental damage, and it is also one of the most prone to aging. This kind of aging is specifically manifested in the skin around the eyes as a decrease in skin thickness, a decrease in moisture content, sagging skin, increased fine wrinkles, dark circles, skin pigmentation around the eyes, and dullness. Accumulation, decreased collagen synthesis ability, decreased hyaluronic acid content, decreased skin moisture content, etc. [0003] At the same time, more and more people now have visual fatigue due to long-term use of computers, watching TV, reading, working and studying in an air-conditioned environment, etc. They always feel dry eyes, soreness, pain, blurred vision...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9794A61K8/55A61K8/65A61K8/9789A61K8/14A61K38/39A61Q19/02A61Q19/00A61P27/02A61P1/16
CPCA61K8/9789A61K8/65A61K8/9794A61K8/14A61K8/553A61K36/482A61K36/534A61K36/8984A61K36/89A61K36/815A61K36/484A61K38/39A61P27/02A61P1/16A61Q19/005A61Q19/02A61K2800/21A61K2800/5922A61K2300/00
Inventor 李明媛李萌李世勤贾琳李媛郁彭
Owner TIANJIN SHI JI KANG TAI BIOMEDICAL ENG CO LTD
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